2QKH
Crystal structure of the extracellular domain of human GIP receptor in complex with the hormone GIP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Glucose-dependent insulinotropic polypeptide | polymer | 42 | 4990.6 | 1 | UniProt (P09681) Pfam (PF00123) In PDB | Gastric inhibitory polypeptide, GIP | |
2 | A | Glucose-dependent insulinotropic polypeptide receptor | polymer | 135 | 15391.0 | 1 | UniProt (P48546) Pfam (PF02793) In PDB | Homo sapiens (human) | Gastric inhibitory polypeptide receptor, GIP-R |
3 | C | Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose | branched | 1251.2 | 1 | In PDB BIRD (PRD_900086) GlyTouCan (G04274SM) | methyl-beta-cyclodextrin | ||
4 | A | D(-)-TARTARIC ACID | non-polymer | 150.1 | 1 | Chemie (TAR) | |||
5 | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A: 24 - 138 (UniProt: P48546)
PDB | External Database | Details |
---|---|---|
Gly 4 | - | expression tag |
Ser 5 | - | expression tag |
Ser 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
His 12 | - | expression tag |
Ser 13 | - | expression tag |
Ser 14 | - | expression tag |
Gly 15 | - | expression tag |
Leu 16 | - | expression tag |
Val 17 | - | expression tag |
Pro 18 | - | expression tag |
Arg 19 | - | expression tag |
Gly 20 | - | expression tag |
Ser 21 | - | expression tag |
His 22 | - | expression tag |
Met 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 20381.6 | |
Branched | Number of molecules | 1 |
Total formula weight | 1251.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 150.1 | |
All* | Total formula weight | 21782.9 |