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2QKH

Crystal structure of the extracellular domain of human GIP receptor in complex with the hormone GIP

Functional Information from GO Data
ChainGOidnamespacecontents
A0004930molecular_functionG protein-coupled receptor activity
A0007186biological_processG protein-coupled receptor signaling pathway
A0016020cellular_componentmembrane
A0016519molecular_functiongastric inhibitory peptide receptor activity
B0005179molecular_functionhormone activity
B0005576cellular_componentextracellular region
B0009749biological_processresponse to glucose
B0042304biological_processregulation of fatty acid biosynthetic process
B0050796biological_processregulation of insulin secretion
Functional Information from PROSITE/UniProt
site_idPS00260
Number of Residues23
DetailsGLUCAGON Glucagon / GIP / secretin / VIP family signature. YAEGTFiSDYsiamdkihQQDFV
ChainResidueDetails
BTYR1-VAL23

site_idPS00649
Number of Residues25
DetailsG_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CngsFDmyv.CWdyAapnatarasCP
ChainResidueDetails
ACYS61-PRO85

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22412906","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

246031

PDB entries from 2025-12-10

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