2PKS
Thrombin in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thrombin light chain | polymer | 27 | 3188.6 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | |
| 2 | B (B) | Thrombin heavy chain fragment | polymer | 147 | 17070.7 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 3 | C (C) | Thrombin heavy chain fragment | polymer | 102 | 11636.3 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | |
| 4 | D (D) | Hirudin | polymer | 10 | 1291.3 | 1 | UniProt (P28504) | ||
| 5 | E (C) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F (C) | 4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE | non-polymer | 344.4 | 1 | Chemie (G44) | |||
| 7 | G, H, I (A, B, C) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
D: 355 - 364 (UniProt: P28504)
| PDB | External Database | Details |
|---|---|---|
| Gly 361 | Glu 61 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 33187.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 367.4 | |
| All* | Total formula weight | 33554.4 |
