2PKS
Thrombin in complex with inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Thrombin light chain | polymer | 27 | 3188.6 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | |
2 | B | Thrombin heavy chain fragment | polymer | 147 | 17070.7 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | |
3 | C | Thrombin heavy chain fragment | polymer | 102 | 11636.3 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | |
4 | D | Hirudin | polymer | 10 | 1291.3 | 1 | UniProt (P28504) In PDB | ||
5 | C | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | C | 4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE | non-polymer | 344.4 | 1 | Chemie (G44) | |||
7 | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
D: 355 - 364 (UniProt: P28504)
PDB | External Database | Details |
---|---|---|
Gly 361 | Glu 61 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 33187.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 367.4 | |
All* | Total formula weight | 33554.4 |