2JBU
Crystal structure of human insulin degrading enzyme complexed with co- purified peptides.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | INSULIN-DEGRADING ENZYME | polymer | 990 | 114715.1 | 2 | UniProt (Q5T5N2) Pfam (PF00675) Pfam (PF05193) Pfam (PF16187) UniProt (by SIFTS) (P14735) In PDB | Homo sapiens | |
2 | C, D | CO-PURIFIED PEPTIDE | polymer | 12 | 870.9 | 2 | Escherichia coli | ||
3 | A, B | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 2 | Chemie (DIO) | |||
4 | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A, B: 30 - 41 (PDB: 2JBU)
A, B: 42 - 1019 (UniProt: Q5T5N2)
A, B: 42 - 1019 (UniProt: Q5T5N2)
PDB | External Database | Details |
---|---|---|
Gln 111 | Glu 111 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 231172.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 176.2 | |
All* | Total formula weight | 231348.4 |