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2J7Q

Crystal structure of the ubiquitin-specific protease encoded by murine cytomegalovirus tegument protein M48 in complex with a ubquitin-based suicide substrate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
MCMV TEGUMENT PROTEIN M48 ENCODED UBIQUITIN- SPECIFIC PROTEASE, M48USPpolymer23225677.31MURINE CYTOMEGALOVIRUS
2B, D
(B, D)
UBIQUITINpolymer758519.82UniProt (P62988)
Pfam (PF00240)
UniProt (by SIFTS) (P0CG48)
HOMO SAPIENS (HUMAN)
3C
(C)
MCMV TEGUMENT PROTEIN M48 ENCODED UBIQUITIN- SPECIFIC PROTEASE, M48USPpolymer23225686.31MURINE CYTOMEGALOVIRUS
4E, G, K
(A, B, D)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5F, J
(A, C)
METHYL 4-AMINOBUTANOATEnon-polymer117.12Chemie (GVE)
6H
(B)
TETRAETHYLENE GLYCOLnon-polymer194.21Chemie (PG4)
7I
(C)
GLYCEROLnon-polymer92.11Chemie (GOL)
8L, M, N, O
(A, B, C, D)
waterwater18.0707Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight68403.2
Non-Polymers*Number of molecules7
Total formula weight593.5
All*Total formula weight68996.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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