2IZV
CRYSTAL STRUCTURE OF SOCS-4 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 2.55A RESOLUTION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SUPPRESSOR OF CYTOKINE SIGNALING 4 | polymer | 187 | 21736.7 | 1 | UniProt (Q8WXH5) Pfam (PF00017) Pfam (PF07525) | HOMO SAPIENS (HUMAN) | SOCS-4 ELONGIN B, C COMPLEX, SOCS-4, SOCS-7, SUPPRESSOR OF CYTOKINE SIGNALING 7 |
| 2 | B (B) | TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2 | polymer | 118 | 13147.8 | 1 | UniProt (Q15370) Pfam (PF00240) | HOMO SAPIENS (HUMAN) | RNA POLYMERASE II TRANSCRIPTION FACTOR SIII SUBUNIT B, SIII P18, ELONGIN B, ELOB, ELONGIN 18 KDA SUBUNIT |
| 3 | C (C) | TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1 | polymer | 97 | 10974.6 | 1 | UniProt (Q15369) Pfam (PF03931) | HOMO SAPIENS (HUMAN) | RNA POLYMERASE II TRANSCRIPTION FACTOR SIII SUBUNIT C, SIII P15, ELONGIN-C, ELOC, ELONGIN 15 KDA SUBUNIT |
| 4 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | G, H, I (A, B, C) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A: 251 - 273 (PDB: 2IZV)
A: 274 - 437 (UniProt: Q8WXH5)
C: 16 - 16 (PDB: 2IZV)
C: 17 - 112 (UniProt: Q15369)
A: 274 - 437 (UniProt: Q8WXH5)
C: 16 - 16 (PDB: 2IZV)
C: 17 - 112 (UniProt: Q15369)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45859.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 120.5 | |
| All* | Total formula weight | 45979.6 |
