2IYK

Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	REGULATOR OF NONSENSE TRANSCRIPTS 1	polymer	162	18216.0	2	UniProt (Q92900) Pfam (PF09416)	HOMO SAPIENS (HUMAN)	ATP-DEPENDENT HELICASE RENT1, NONSENSE MRNA REDUCING FACTOR 1, NORF1, UP-FRAMESHIFT SUPPRESSOR 1 HOMOLOG, HUPF1, UPF1
2	C, D, E, F, G... (A, B)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)

Sequence modifications

A, B: 1 - 4 (PDB: 2IYK)
A, B: 5 - 162 (UniProt: Q92900)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36431.9
Non-Polymers*	Number of molecules	6
	Total formula weight	392.5
All*	Total formula weight	36824.4

*Water molecules are not included.