2IYK

Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1

Summary for 2IYK

Entry DOI	10.2210/pdb2iyk/pdb
Descriptor	REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION (2 entities in total)
Functional Keywords	nmd, zinc, upf1, helicase, hydrolase, zinc-finger, nucleotide-binding, surveillance complex, nonsense-mediated mrna decay, alternative splicing, nonsense mediated mrna decay, atp-binding, metal-binding, phosphorylation
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: Q92900
Total number of polymer chains	2
Total formula weight	36824.39
Authors	Kadlec, J.,Guilligay, D.,Ravelli, R.B.,Cusack, S. (deposition date: 2006-07-18, release date: 2006-08-30, Last modification date: 2011-07-13)
Primary citation	Kadlec, J.,Guilligay, D.,Ravelli, R.B.,Cusack, S. Crystal Structure of the Upf2-Interacting Domain of Nonsense-Mediated Mrna Decay Factor Upf1. RNA, 12:1817-, 2006 Cited by PubMed: 16931876 DOI: 10.1261/RNA.177606 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation