2I5X
Engineering the PTPbeta catalytic domain with improved crystallization properties
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor-type tyrosine-protein phosphatase beta | polymer | 313 | 36288.0 | 2 | UniProt (P23467) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase beta, R-PTP-beta |
| 2 | C, F (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D, G (A, B) | (4-ETHYLPHENYL)SULFAMIC ACID | non-polymer | 201.2 | 2 | Chemie (UA5) | |||
| 4 | E (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A, B: 1662 - 1973 (UniProt: P23467)
| PDB | External Database | Details |
|---|---|---|
| Ser 1661 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72576.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 497.7 | |
| All* | Total formula weight | 73073.8 |
