2I4Q
Human renin/PF02342674 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Renin | polymer | 336 | 36882.5 | 2 | UniProt (P00797) Pfam (PF00026) | Homo sapiens (human) | Angiotensinogenase |
| 2 | C, D (A, B) | (2S)-6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2-(3,5-DIFLUOROPHENYL)-4-(3-METHOXYPROPYL)-2-METHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE | non-polymer | 483.5 | 2 | Chemie (UA4) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 335 (UniProt: P00797)
| PDB | External Database | Details |
|---|---|---|
| Asn 0 | - | cloning artifact |
| Thr 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73765.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 967.0 | |
| All* | Total formula weight | 74732.1 |
