Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE UA4 B 336 |
| Chain | Residue |
| B | THR13 |
| B | ALA117 |
| B | ASP221 |
| B | THR222 |
| B | GLY223 |
| B | SER225 |
| B | ASN255 |
| B | GLN14 |
| B | TYR15 |
| B | VAL31 |
| B | ASP33 |
| B | TYR78 |
| B | THR80 |
| B | PRO113 |
| B | LEU116 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE UA4 A 336 |
| Chain | Residue |
| A | THR13 |
| A | GLN14 |
| A | TYR15 |
| A | VAL31 |
| A | ASP33 |
| A | TYR55 |
| A | TYR78 |
| A | SER79 |
| A | THR80 |
| A | LEU116 |
| A | ALA117 |
| A | VAL122 |
| A | ASP221 |
| A | THR222 |
| A | GLY223 |
| A | SER225 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VVFDTGSSNVWV |
| Chain | Residue | Details |
| A | VAL30-VAL41 | |
| A | ALA218-GLY229 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 634 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"20927107","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"2493678","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| A | ASP221 | |
| A | THR34 | |
| A | ASP33 | |
| A | THR222 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| B | ASP221 | |
| B | THR34 | |
| B | ASP33 | |
| B | THR222 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| A | ASP221 | |
| A | ASP33 | |
| A | SER36 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| B | ASP221 | |
| B | ASP33 | |
| B | SER36 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| A | ASP221 | |
| A | ASP33 | |
| A | TYR78 | |
| A | SER36 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| B | ASP221 | |
| B | ASP33 | |
| B | TYR78 | |
| B | SER36 | |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| A | ASP221 | |
| A | ASP33 | |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| B | ASP221 | |
| B | ASP33 | |
