1TSD

THYMIDYLATE SYNTHASE COMPLEX WITH 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP) AND FOLATE ANALOG 1843U89

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	THYMIDYLATE SYNTHASE	polymer	265	30543.7	2	UniProt (P00470) Pfam (PF00303) UniProt (by SIFTS) (P0A884)	Escherichia coli
2	C, D (A)	BETA-MERCAPTOETHANOL	non-polymer		78.1	2	Chemie (BME)
3	E, G (A, B)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	2	Chemie (UMP)
4	F, H (A, B)	S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID	non-polymer		500.5	2	Chemie (F89)
5	I, J (A, B)	water	water		18.0	188	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61087.3
Non-Polymers*	Number of molecules	6
	Total formula weight	1773.6
All*	Total formula weight	62861.0

*Water molecules are not included.