1RRV
X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | GLYCOSYLTRANSFERASE GTFD | polymer | 416 | 43905.9 | 2 | UniProt (Q9AFC7) Pfam (PF03033) Pfam (PF06722) In PDB | AMYCOLATOPSIS ORIENTALIS | |
2 | C, D | DESVANCOSAMINYL VANCOMYCIN | polymer | 7 | 1150.0 | 2 | NOR (NOR00681) BIRD (PRD_000205) | AMYCOLATOPSIS ORIENTALIS | |
3 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
4 | A, B | THYMIDINE-5'-DIPHOSPHATE | non-polymer | 402.2 | 2 | Chemie (TYD) | |||
5 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
6 | C, D | beta-D-glucopyranose | non-polymer | 180.2 | 2 | BIRD (PRD_000205) Chemie (BGC) | |||
7 | water | water | 18.0 | 500 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 408 (UniProt: Q9AFC7)
A, B: 409 - 416 (PDB: 1RRV)
PDB | External Database | Details |
---|---|---|
Leu 195 | Cys 195 | cloning artifact |
Leu 196 | Trp 196 | cloning artifact |
Ala 197 | Pro 197 | cloning artifact |
Leu 409 | - | cloning artifact |
Glu 410 | - | cloning artifact |
His 411 | - | expression tag |
His 412 | - | expression tag |
His 413 | - | expression tag |
His 414 | - | expression tag |
His 415 | - | expression tag |
His 416 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 90111.7 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1519.2 | |
All* | Total formula weight | 91630.9 |