1RRV
X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin.
Summary for 1RRV
Entry DOI | 10.2210/pdb1rrv/pdb |
Related | 1AA5 1C0Q 1C0R 1FVM 1GAC 1GHG 1PN3 1PNV 1QD8 1SHO |
Related PRD ID | PRD_000205 |
Descriptor | GLYCOSYLTRANSFERASE GTFD, DESVANCOSAMINYL VANCOMYCIN, POTASSIUM ION, ... (7 entities in total) |
Functional Keywords | gt-b, glycosyltransferase, rossmann fold, glycopeptide, vacosamycin, antibiotic, transferase-antibiotic complex, transferase/antibiotic |
Biological source | AMYCOLATOPSIS ORIENTALIS More |
Total number of polymer chains | 4 |
Total formula weight | 91630.88 |
Authors | Mulichak, A.M.,Lu, W.,Losey, H.C.,Walsh, C.T.,Garavito, R.M. (deposition date: 2003-12-09, release date: 2004-05-18, Last modification date: 2023-11-15) |
Primary citation | Mulichak, A.M.,Lu, W.,Losey, H.C.,Walsh, C.T.,Garavito, R.M. Crystal Structure of Vancosaminyltransferase Gtfd from the Vancomycin Biosynthetic Pathway: Interactions with Acceptor and Nucleotide Ligands Biochemistry, 43:5170-, 2004 Cited by PubMed: 15122882DOI: 10.1021/BI036130C PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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