1PQ6
HUMAN LXR BETA HORMONE RECEPTOR / GW3965 COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Oxysterols receptor LXR-beta | polymer | 253 | 29057.3 | 4 | UniProt (P55055) Pfam (PF00104) | Homo sapiens (human) | Liver X receptor beta, Nuclear orphan receptor LXR-beta, Ubiquitously-expressed nuclear receptor, Nuclear receptor NER |
| 2 | E, G, I (A, B, D) | [3-(3-{[2-chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)phenyl]acetic acid | non-polymer | 582.1 | 3 | Chemie (965) | |||
| 3 | F, H (A, B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 2 | Chemie (IPA) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 213 - 461 (UniProt: P55055)
| PDB | External Database | Details |
|---|---|---|
| Gly 209 | - | cloning artifact |
| Ser 210 | - | cloning artifact |
| His 211 | - | cloning artifact |
| Met 212 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116229.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1866.3 | |
| All* | Total formula weight | 118095.5 |
