1P6O
The crystal structure of yeast cytosine deaminase bound to 4(R)-hydroxyl-3,4-dihydropyrimidine at 1.14 angstroms.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytosine deaminase | polymer | 161 | 17761.2 | 2 | UniProt (Q12178) Pfam (PF00383) | Saccharomyces cerevisiae (baker's yeast) | Cytosine aminohydrolase |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, I (A, B) | 4-HYDROXY-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE | non-polymer | 114.1 | 2 | Chemie (HPY) | |||
| 4 | E, J, K (A, B) | ACETIC ACID | non-polymer | 60.1 | 3 | Chemie (ACY) | |||
| 5 | G, H (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 438 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 158 (UniProt: Q12178)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35522.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 619.3 | |
| All* | Total formula weight | 36141.8 |
