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1LBC

Crystal structure of GluR2 ligand binding core (S1S2J-N775S) in complex with cyclothiazide (CTZ) as well as glutamate at 1.8 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Glutamine Receptor 2polymer26329194.73Pfam (PF10613)
Pfam (PF00060)
UniProt (by SIFTS) (P19491)
Rattus norvegicus (Norway rat)GLUR-2, GLUR-B, GLUR-K2, GLUTAMATE RECEPTOR IONOTROPIC AMPA 2
2D, G, H, K, L
(A, B, C)
ZINC IONnon-polymer65.45Chemie (ZN)
3E, I, M
(A, B, C)
GLUTAMIC ACIDnon-polymer147.13Chemie (GLU)
4F, J, N
(A, B, C)
CYCLOTHIAZIDEnon-polymer389.93Chemie (CYZ)
5O, P, Q
(A, B, C)
waterwater18.0319Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight87584.0
Non-Polymers*Number of molecules11
Total formula weight1938.1
All*Total formula weight89522.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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