1LBC
Crystal structure of GluR2 ligand binding core (S1S2J-N775S) in complex with cyclothiazide (CTZ) as well as glutamate at 1.8 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutamine Receptor 2 | polymer | 263 | 29194.7 | 3 | Pfam (PF10613) Pfam (PF00060) UniProt (by SIFTS) (P19491) | Rattus norvegicus (Norway rat) | GLUR-2, GLUR-B, GLUR-K2, GLUTAMATE RECEPTOR IONOTROPIC AMPA 2 |
| 2 | D, G, H, K, L (A, B, C) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 3 | E, I, M (A, B, C) | GLUTAMIC ACID | non-polymer | 147.1 | 3 | Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032) | |||
| 4 | F, J, N (A, B, C) | CYCLOTHIAZIDE | non-polymer | 389.9 | 3 | Chemie (CYZ) PubChem (2910) PubChem (21550932) PubChem (177678892) PubChem (44582559) PubChem (52949708) PubChem (657321) PubChem (5288009) PubChem (92142359) PubChem (98047041) PubChem (101691639) PubChem (5388988) PubChem (92143401) PubChem (92215537) PubChem (6603794) PubChem (98047042) PubChem (101691640) PubChem (11972587) PubChem (131842006) | |||
| 5 | O, P, Q (A, B, C) | water | water | 18.0 | 319 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87584.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1938.1 | |
| All* | Total formula weight | 89522.0 |
