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1HCF

Crystal structure of TrkB-d5 bound to neurotrophin-4/5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
NEUROTROPHIN-4polymer13013944.62UniProt (P34130)
Pfam (PF00243)
HOMO SAPIENS (HUMAN)NEUROTROPHIN-5, NEUROTROPHIN-4/5, NT-4/5
2C, D
(X, Y)
BDNF/NT-3 GROWTH FACTORS RECEPTORpolymer10111546.02UniProt (Q16620)
Pfam (PF07679)
HOMO SAPIENS (HUMAN)TRKB, GP145-TRKB
3E, F, G, H
(A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
4I, J, K, L
(A, B, X, Y)
waterwater18.060Chemie (HOH)
Sequence modifications
X, Y: 283 - 285 (PDB: 1HCF)
X, Y: 286 - 383 (UniProt: Q16620)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight50981.3
Non-Polymers*Number of molecules4
Total formula weight384.3
All*Total formula weight51365.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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