9JD2
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9DDY
| The Crystal Structure of Geranyltranstransferase from Streptococcus pneumoniae TIGR4 | Descriptor: | GLYCEROL, Geranyltranstransferase | Authors: | Kim, Y, Tan, A, Endres, M, Tan, K, Joachimik, A, Center for Structural Biology of Infectious Diseases (CSBID) | Deposit date: | 2024-08-28 | Release date: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | The Crystal Structure of Geranyltranstransferase from Streptococcus pneumoniae TIGR4 To Be Published
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9DCG
| Crystal Structure of the Thiol:Disulfide Interchange Protein DsbC from Vibrio cholerae | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ... | Authors: | Kim, Y, Maltseva, N, Shatsman, S, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | Deposit date: | 2024-08-26 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystal Structure of the Thiol:Disulfide Interchange Protein DsbC from Vibrio cholerae To Be Published
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9JA1
| The RNA polymerase II elongation complex from Saccharomyces cerevisiae | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*GP*CP*TP*CP*CP*TP*TP*CP*TP*CP*CP*CP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*T)-3'), DNA (5'-D(P*TP*GP*GP*GP*AP*GP*AP*AP*GP*GP*AP*GP*C)-3'), ... | Authors: | Yi, G, Ma, J, Zhang, P. | Deposit date: | 2024-08-23 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | The RNA polymerase II elongation complex from Saccharomyces cerevisiae To Be Published
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9GJ2
| Crystal structure of human cathepsin S produced in insect cells in complex with ketoamide 13b | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, Cathepsin S, ... | Authors: | Falke, S, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Reinke, P.Y.A, Guenther, S, Turk, D, Meents, A. | Deposit date: | 2024-08-20 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Crystal structure of human cathepsin S produced in insect cells in complex with ketoamide 13b To Be Published
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9J7T
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9GGQ
| E.coli gyrase holocomplex with cleaved chirally wrapped 217 bp DNA fragment and moxifloxacin | Descriptor: | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA gyrase subunit A, DNA gyrase subunit B, ... | Authors: | Ghilarov, D, Heddle, J.G, Pabis, M. | Deposit date: | 2024-08-13 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis of chiral wrap and T-segment capture by Escherichia coli DNA gyrase Proceedings of the National Academy of Sciences USA, 2024
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9D5D
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9GG6
| P301T type II tau filaments from human brain | Descriptor: | Isoform Tau-F of Microtubule-associated protein tau | Authors: | Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M. | Deposit date: | 2024-08-13 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Novel tau filament folds in individuals with MAPT mutations P301L and P301T. Biorxiv, 2024
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9J5G
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9GG1
| P301T type I tau filaments from human brain | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M. | Deposit date: | 2024-08-12 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.26 Å) | Cite: | Novel tau filament folds in individuals with MAPT mutations P301L and P301T. Biorxiv, 2024
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9GG0
| P301L tau filaments from human brain | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M. | Deposit date: | 2024-08-12 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Novel tau filament folds in individuals with MAPT mutations P301L and P301T. Biorxiv, 2024
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9D3G
| Cryo-EM structure of CCR6 bound by SQA1 and OXM1 | Descriptor: | 1-(4-chlorophenyl)-N-{[(2R)-4-(2,3-dihydro-1H-inden-2-yl)-5-oxomorpholin-2-yl]methyl}cyclopropane-1-carboxamide, 4-[[3,4-bis(oxidanylidene)-2-[[(1~{R})-1-(4-propan-2-ylfuran-2-yl)propyl]amino]cyclobuten-1-yl]amino]-~{N},~{N}-dimethyl-3-oxidanyl-pyridine-2-carboxamide, CCR6, ... | Authors: | Wasilko, D.J, Wu, H. | Deposit date: | 2024-08-10 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural basis for CCR6 modulation by allosteric antagonists. Nat Commun, 15, 2024
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9J4K
| Crystal structure of GH9l Inulinfructotransferases (IFTase) in complex with GF2 | Descriptor: | DFA-III-forming inulin fructotransferase, beta-D-fructofuranose-(2-1)-beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | Authors: | Chen, G, Wang, Z.X, Yang, Y.Q, Li, Y.G, Zhang, T, Ouyang, S.Y, Zhang, L, Chen, Y, Ruan, X.L, Miao, M. | Deposit date: | 2024-08-09 | Release date: | 2024-09-04 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Elucidation of the mechanism underlying the sequential catalysis of inulin by fructotransferase. Int.J.Biol.Macromol., 277, 2024
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9J4J
| Crystal structure of GH9l Inulin fructotransferases(IFTase)incomplex with nystose(F3) | Descriptor: | DFA-III-forming inulin fructotransferase, beta-D-fructofuranose, beta-D-fructofuranose-(1-1)-beta-D-fructofuranose, ... | Authors: | Chen, G, Wang, Z.X, Yang, Y.Q, Li, Y.G, Zhang, T, Ouyang, S.Y, Zhang, L, Chen, Y, Ruan, X.L, Miao, M. | Deposit date: | 2024-08-09 | Release date: | 2024-09-04 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | Elucidation of the mechanism underlying the sequential catalysis of inulin by fructotransferase. Int.J.Biol.Macromol., 277, 2024
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9J4L
| Crystal structure of GH9l Inulin fructotransferases (IFTase) | Descriptor: | DFA-III-forming inulin fructotransferase | Authors: | Chen, G, Wang, Z.X, Yang, Y.Q, Li, Y.G, Zhang, T, Ouyang, S.Y, Zhang, L, Chen, Y, Ruan, X.L, Miao, M. | Deposit date: | 2024-08-09 | Release date: | 2024-09-04 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Elucidation of the mechanism underlying the sequential catalysis of inulin by fructotransferase. Int.J.Biol.Macromol., 277, 2024
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9D3E
| Cryo-EM structure of CCR6 bound by SQA1 and OXM2 | Descriptor: | 4-[[3,4-bis(oxidanylidene)-2-[[(1~{R})-1-(4-propan-2-ylfuran-2-yl)propyl]amino]cyclobuten-1-yl]amino]-~{N},~{N}-dimethyl-3-oxidanyl-pyridine-2-carboxamide, CHOLESTEROL, Human CCR6, ... | Authors: | Wasilko, D.J, Wu, H. | Deposit date: | 2024-08-09 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structural basis for CCR6 modulation by allosteric antagonists. Nat Commun, 15, 2024
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9J4I
| Crystal structure of GH9l Inulin fructotransferases (IFTase) in compex with fruetosyl nystose (GF4) | Descriptor: | DFA-III-forming inulin fructotransferase, beta-D-fructofuranose-(2-1)-beta-D-fructofuranose-(2-1)-[alpha-D-glucopyranose-(1-2)]beta-D-fructofuranose, beta-D-fructofuranose-(2-1)-beta-D-fructofuranose-(2-1)-beta-D-fructofuranose-(2-1)-[alpha-D-glucopyranose-(1-2)]beta-D-fructofuranose | Authors: | Chen, G, Wang, Z.X, Yang, Y.Q, Li, Y.G, Zhang, T, Ouyang, S.Y, Zhang, L, Chen, Y, Ruan, X.L, Miao, M. | Deposit date: | 2024-08-09 | Release date: | 2024-09-04 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Elucidation of the mechanism underlying the sequential catalysis of inulin by fructotransferase. Int.J.Biol.Macromol., 277, 2024
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9D2C
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9GEA
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9CYP
| Crystal structure of I19V mutant human PTP1B (PTPN1) at room temperature (298 K) | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Ebrahim, A, Perdikari, A, Woods, V.A, Lawler, K, Bounds, R, Singh, N.I, Mehlman, T, Riley, B.T, Sharma, S, Morris, J.W, Keogh, J.M, Henning, E, Smith, M, Farooqi, I.S, Keedy, D.A. | Deposit date: | 2024-08-02 | Release date: | 2024-08-21 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy. Biorxiv, 2024
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9CYM
| Structure of LAG3 bound to the MHC class II molecule I-A(b) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Class-II-associated invariant chain peptide, H-2 class II histocompatibility antigen, ... | Authors: | Ming, Q, Antfolk, D, Tran, T.H, Luca, V.C. | Deposit date: | 2024-08-02 | Release date: | 2024-08-21 | Method: | X-RAY DIFFRACTION (3.84 Å) | Cite: | Structural basis for LAG3 interactions with MHC class II To Be Published
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9CYO
| Crystal structure of wild-type human PTP1B (PTPN1) at room temperature (298 K) | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Ebrahim, A, Perdikari, A, Woods, V.A, Lawler, K, Bounds, R, Singh, N.I, Mehlman, T, Riley, B.T, Sharma, S, Morris, J.W, Keogh, J.M, Henning, E, Smith, M, Farooqi, I.S, Keedy, D.A. | Deposit date: | 2024-08-02 | Release date: | 2024-08-21 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy. Biorxiv, 2024
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9CYQ
| Crystal structure of Q78R mutant human PTP1B (PTPN1) at room temperature (298 K) | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Ebrahim, A, Perdikari, A, Woods, V.A, Lawler, K, Bounds, R, Singh, N.I, Mehlman, T, Riley, B.T, Sharma, S, Morris, J.W, Keogh, J.M, Henning, E, Smith, M, Farooqi, I.S, Keedy, D.A. | Deposit date: | 2024-08-02 | Release date: | 2024-08-21 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy. Biorxiv, 2024
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9CYR
| Crystal structure of D245G mutant human PTP1B (PTPN1) at room temperature (298 K) | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Ebrahim, A, Perdikari, A, Woods, V.A, Lawler, K, Bounds, R, Singh, N.I, Mehlman, T, Riley, B.T, Sharma, S, Morris, J.W, Keogh, J.M, Henning, E, Smith, M, Farooqi, I.S, Keedy, D.A. | Deposit date: | 2024-08-02 | Release date: | 2024-08-21 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy. Biorxiv, 2024
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