1CDH
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STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES
Descriptor:T CELL SURFACE GLYCOPROTEIN CD4
Authors:Ryu, S.E., Truneh, A., Sweet, R.W., Hendrickson, W.A.
Deposit date:1994-01-26
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices.
Structure, 2, 1994
1CDI
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STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES
Descriptor:T CELL SURFACE GLYCOPROTEIN CD4
Authors:Ryu, S.E., Truneh, A., Sweet, R.W., Hendrickson, W.A.
Deposit date:1994-01-26
Release date:1994-04-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices.
Structure, 2, 1994
1CDJ
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1CDU
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH PHE 43 REPLACED BY VAL
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1CDY
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STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH GLY 47 REPLACED BY SER
Descriptor:T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.
Deposit date:1996-11-11
Release date:1997-04-01
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
1G9M
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HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, ...
Authors:Kwong, P.D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:2000-11-24
Release date:2000-12-27
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1G9N
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HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, ...
Authors:Kwong, P.D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:2000-11-25
Release date:2000-12-27
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1GC1
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HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY
Descriptor:ENVELOPE PROTEIN GP120, CD4, ANTIBODY 17B, ...
Authors:Kwong, P.D., Wyatt, R., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:1998-06-15
Release date:1998-07-08
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
Nature, 393, 1998
1RZJ
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HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, ...
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZK
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HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-CELL SURFACE GLYCOPROTEIN CD4, ANTIBODY 17B, ...
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
2B4C
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CRYSTAL STRUCTURE OF HIV-1 JR-FL GP120 CORE PROTEIN CONTAINING THE THIRD VARIABLE REGION (V3) COMPLEXED WITH CD4 AND THE X5 ANTIBODY
Descriptor:envelope glycoprotein, T-cell surface glycoprotein CD4, anti-HIV-1 gp120 immunoglobulin X5 light chain, ...
Authors:Huang, C., Tang, M., Zhang, M.Y., Majeed, S., Montabana, E., Stanfield, R.L., Dimitrov, D.S., Korber, B., Sodroski, J., Wilson, I.A., Wyatt, R., Kwong, P.D.
Deposit date:2005-09-23
Release date:2005-11-15
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a V3-containing HIV-1 gp120 core.
Science, 310, 2005
3CD4
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REFINEMENT AND ANALYSIS OF THE FIRST TWO DOMAINS OF HUMAN CD4
Descriptor:T CELL SURFACE GLYCOPROTEIN CD4
Authors:Garrett, T.P.J., Wang, J., Yan, Y., Harrison, S.C.
Deposit date:1992-07-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refinement and analysis of the structure of the first two domains of human CD4
J.Mol.Biol., 234, 1993
3J70
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MODEL OF GP120, INCLUDING VARIABLE REGIONS, IN COMPLEX WITH CD4 AND 17B
Descriptor:monoclonal antibody 17b light chain, monoclonal antibody 17b heavy chain, T-cell surface glycoprotein CD4, ...
Authors:Rasheed, M., Bettadapura, R., Bajaj, C.
Deposit date:2014-04-22
Release date:2015-08-26
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State.
Structure, 23, 2015
3JWD
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STRUCTURE OF HIV-1 GP120 WITH GP41-INTERACTIVE REGION: LAYERED ARCHITECTURE AND BASIS OF CONFORMATIONAL MOBILITY
Descriptor:HIV-1 GP120 ENVELOPE GLYCOPROTEIN, T-cell surface glycoprotein CD4, FAB 48D LIGHT CHAIN, ...
Authors:Pancera, M., Majeed, S., Ban, Y.A., Chen, L., Huang, C.C., Kong, L., Kwon, Y.D., Stuckey, J., Zhou, T., Robinson, J.E., Schief, W.R., Sodroski, J., Wyatt, R., Kwong, P.D.
Deposit date:2009-09-18
Release date:2009-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Proc.Natl.Acad.Sci.USA, 107, 2010
3JWO
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STRUCTURE OF HIV-1 GP120 WITH GP41-INTERACTIVE REGION: LAYERED ARCHITECTURE AND BASIS OF CONFORMATIONAL MOBILITY
Descriptor:HIV-1 GP120 ENVELOPE GLYCOPROTEIN, T-cell surface glycoprotein CD4, FAB 48D LIGHT CHAIN, ...
Authors:Pancera, M., Majeed, S., Huang, C.C., Kwon, Y.D., Zhou, T., Robinson, J.E., Sodroski, J., Wyatt, R., Kwong, P.D.
Deposit date:2009-09-18
Release date:2009-12-29
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LQA
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CRYSTAL STRUCTURE OF CLADE C GP120 IN COMPLEX WITH SCD4 AND 21C FAB
Descriptor:T-cell surface glycoprotein CD4, Envelope glycoprotein gp160, Heavy chain of anti HIV Fab from human 21c antibody, ...
Authors:Diskin, R., Marcovecchio, P.M., Bjorkman, P.J.
Deposit date:2010-02-08
Release date:2010-04-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity.
Nat.Struct.Mol.Biol., 17, 2010
3O2D
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CRYSTAL STRUCTURE OF HIV-1 PRIMARY RECEPTOR CD4 IN COMPLEX WITH A POTENT ANTIVIRAL ANTIBODY
Descriptor:ibalizumab light chain, ibalizumab heavy chain, T-cell surface glycoprotein CD4
Authors:Freeman, M.M., Seaman, M.S., Rits-Volloch, S., Hong, X., Ho, D.D., Chen, B.
Deposit date:2010-07-22
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal Structure of HIV-1 Primary Receptor CD4 in Complex with a Potent Antiviral Antibody.
Structure, 18, 2010
4H8W
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CRYSTAL STRUCTURE OF NON-NEUTRALIZING AND ADCC-POTENT ANTIBODY N5-I5 IN COMPLEX WITH HIV-1 CLADE A/E GP120 AND SCD4.
Descriptor:HIV-1 CLADE A/E 93TH057 (H375S) GP120, FAB HEAVY CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5, FAB LIGHT CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5, ...
Authors:Tolbert, W.D., Acharya, P., Kwong, P.D., Pazgier, M.
Deposit date:2012-09-24
Release date:2014-04-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4JM2
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CRYSTAL STRUCTURE OF PGT 135 FAB IN COMPLEX WITH GP120 CORE PROTEIN FROM HIV-1 STRAIN JR-FL BOUND TO CD4 AND 17B FAB
Descriptor:PGT 135 Heavy chain, PGT 135 Light chain, 17b Light chain, ...
Authors:Kong, L., Wilson, I.A.
Deposit date:2013-03-13
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Nat.Struct.Mol.Biol., 20, 2013
4P9H
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CRYSTAL STRUCTURE OF 8ANC195 FAB IN COMPLEX WITH GP120 OF 93TH057 HIV-1 AND SOLUBLE CD4 D1D2
Descriptor:T-cell surface glycoprotein CD4, Envelope glycoprotein gp160, Fab heavy chain, ...
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2014-04-04
Release date:2014-05-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
4R2G
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CRYSTAL STRUCTURE OF PGT124 FAB BOUND TO HIV-1 JRCSF GP120 CORE AND TO CD4
Descriptor:Surface protein gp160, T-cell surface glycoprotein CD4, PGT124 Light Chain, ...
Authors:Garces, F., Wilson, I.A.
Deposit date:2014-08-11
Release date:2014-10-08
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (3.283 Å)
Cite:Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
4RQS
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CRYSTAL STRUCTURE OF FULLY GLYCOSYLATED HIV-1 GP120 CORE BOUND TO CD4 AND 17B FAB
Descriptor:2-domain CD4, 17b Fab Light Chain, 17b Fab Heavy Chain, ...
Authors:Kong, L., Wilson, I.A., Kwong, P.D.
Deposit date:2014-11-05
Release date:2014-12-31
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (4.493 Å)
Cite:Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
Proteins, 83, 2015
5A7X
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NEGATIVE STAIN EM OF BG505 SOSIP.664 IN COMPLEX WITH SCD4, 17B, AND 8ANC195
Descriptor:HIV-1 YU2 GP120, T-CELL SURFACE GLYCOPROTEIN CD4, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, ...
Authors:Scharf, L., Wang, H., Gao, H., Chen, S., McDowall, A., Bjorkman, P.
Deposit date:2015-07-10
Release date:2015-08-05
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Broadly Neutralizing Antibody 8Anc195 Recognizes Closed and Open States of HIV-1 Env.
Cell(Cambridge,Mass.), 162, 2015
5A8H
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CRYO-ET SUBTOMOGRAM AVERAGING OF BG505 SOSIP.664 IN COMPLEX WITH SCD4, 17B, AND 8ANC195
Descriptor:HIV-1 GP120, T-CELL SURFACE GLYCOPROTEIN CD4, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, ...
Authors:Scharf, L., Wang, H., Gao, H., Chen, S., McDowall, A., Bjorkman, P.
Deposit date:2015-07-15
Release date:2015-08-05
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
Cell, 162, 2015
5CAY
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ENVELOPE GLYCOPROTEIN GP120 CORE FROM HIV TYPE 2 BOUND TO THE FIRST TWO DOMAINS OF HUMAN SOLUBLE CD4 RECEPTOR
Descriptor:Envelope glycoprotein gp120 core from ST strain of HIV-2, T-cell surface glycoprotein CD4, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Davenport, Y.W., Bjorkman, P.J.
Deposit date:2015-06-30
Release date:2015-12-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of an HIV-2 gp120 in Complex with CD4.
J.Virol., 90, 2015
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