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8Z50
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BU of 8z50 by Molmil
Crystal structure of the ASF1-H3T-H4 complex
Descriptor: Histone H3.1t, Histone H4, Histone chaperone ASF1A
Authors:Xu, L.
Deposit date:2024-04-18
Release date:2024-07-03
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into instability of the nucleosome driven by histone variant H3T.
Biochem.Biophys.Res.Commun., 727, 2024
8CJ3
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BU of 8cj3 by Molmil
Urea-based foldamer inhibitor c3u_7 chimera in complex with ASF1 histone chaperone
Descriptor: Histone chaperone ASF1A, c3u_7 chimera inhibitor of histone chaperone ASF1
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2023-02-11
Release date:2023-07-05
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
8CJ1
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BU of 8cj1 by Molmil
Urea-based foldamer inhibitor c3u_3 chimera in complex with ASF1 histone chaperone
Descriptor: Histone chaperone ASF1A, c3u_3 chimera inhibitor of histone chaperone ASF1
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2023-02-11
Release date:2023-07-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.564 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
8CJ2
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BU of 8cj2 by Molmil
Urea-based foldamer inhibitor c3u_5 chimera in complex with ASF1 histone chaperone
Descriptor: GLYCEROL, Histone chaperone ASF1A, SULFATE ION, ...
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2023-02-11
Release date:2023-07-05
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.127 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
8BV1
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BU of 8bv1 by Molmil
Peptide inhibitor P4 in complex with ASF1 histone chaperone
Descriptor: GLYCEROL, Histone chaperone ASF1A, P4 peptide inhibitor of histone chaperone ASF1
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2022-12-01
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.834 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
7UNK
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BU of 7unk by Molmil
Structure of Importin-4 bound to the H3-H4-ASF1 histone-histone chaperone complex
Descriptor: Histone H3, Histone H4, Histone chaperone, ...
Authors:Bernardes, N.E, Chook, Y.M, Fung, H.Y.J, Chen, Z, Li, Y.
Deposit date:2022-04-11
Release date:2022-09-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VCQ
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BU of 7vcq by Molmil
structure of viral protein BKRF4 in complex with H3.3-H4-ASF1
Descriptor: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
Authors:Liu, Y.R.
Deposit date:2021-09-03
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone.
J.Mol.Biol., 434, 2022
7XAY
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BU of 7xay by Molmil
Crystal structure of Hat1-Hat2-Asf1-H3-H4
Descriptor: COENZYME A, Histone H3, Histone H4, ...
Authors:Yue, Y, Yang, W.S, Xu, R.M.
Deposit date:2022-03-19
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Topography of histone H3-H4 interaction with the Hat1-Hat2 acetyltransferase complex.
Genes Dev., 36, 2022
7V1M
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BU of 7v1m by Molmil
Structural basis for the co-chaperone relationship of sNASP and ASF1b
Descriptor: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
Authors:Bao, H, Huang, H.
Deposit date:2021-08-04
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.834 Å)
Cite:NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modes.
Nucleic Acids Res., 50, 2022
7LNY
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BU of 7lny by Molmil
Apo structure of the Histone chaperone ASF1A residues 1-155
Descriptor: Histone chaperone ASF1A
Authors:Simon, B, Boggon, T.J, Calderwood, D, Turk, B.E.
Deposit date:2021-02-08
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Nat Commun, 13, 2022
7LO0
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BU of 7lo0 by Molmil
Structure of human ASF1a in complex with a TLK2 peptide
Descriptor: Histone chaperone ASF1A, Serine/threonine-protein kinase tousled-like 2
Authors:Simon, B, Calderwood, D, Turk, B.E, Boggon, T.J.
Deposit date:2021-02-08
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Nat Commun, 13, 2022
7V6Q
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BU of 7v6q by Molmil
Crystal structure of sNASP-ASF1A-H3.1-H4 complex
Descriptor: GLYCEROL, Histone H3.1, Histone H4, ...
Authors:Liu, C.P, Xu, R.M.
Deposit date:2021-08-20
Release date:2021-12-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Distinct histone H3-H4 binding modes of sNASP reveal the basis for cooperation and competition of histone chaperones.
Genes Dev., 35, 2021
6ZUF
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BU of 6zuf by Molmil
Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone
Descriptor: C2 foldamer/peptide hybrid inhibitor of histone chaperone ASF1, GLYCEROL, Histone chaperone ASF1A, ...
Authors:Bakail, M, Mbianda, J, Perrin, E.M, Guerois, R, Legrand, P, Traore, S, Douat, C, Guichard, G, Ochsenbein, F.
Deposit date:2020-07-22
Release date:2021-06-09
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity.
Sci Adv, 7, 2021
6O22
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BU of 6o22 by Molmil
Structure of Asf1-H3:H4-Rtt109-Vps75 histone chaperone-lysine acetyltransferase complex with the histone substrate.
Descriptor: Histone H3.2, Histone H4, Histone acetyltransferase RTT109, ...
Authors:Danilenko, N, Carlomagno, T, Kirkpatrick, J.P.
Deposit date:2019-02-22
Release date:2019-07-31
Last modified:2024-05-01
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Histone chaperone exploits intrinsic disorder to switch acetylation specificity.
Nat Commun, 10, 2019
6F0G
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BU of 6f0g by Molmil
Crystal structure ASF1-ip3
Descriptor: Histone chaperone ASF1A, SULFATE ION, ip3
Authors:Gaubert, A, Guichard, B, Richet, N, Le Du, M.H, Andreani, J, Guerois, R, Ochsenbein, F.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
6F0F
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BU of 6f0f by Molmil
Crystal structure ASF1-ip2_s
Descriptor: Histone chaperone ASF1A, ip2_s
Authors:Gaubert, A, Guichard, B, Murciano, B, Le Du, M.H, Ochsenbein, F, Guerois, R, Andreani, J.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
6F0H
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BU of 6f0h by Molmil
Crystal structure ASF1-ip4
Descriptor: CITRIC ACID, GLYCEROL, Histone chaperone ASF1A, ...
Authors:Bakail, M, Richet, N, Le Du, M.H, Andreani, J, Guerois, R, Ochsenbein, F.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
5ZBA
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BU of 5zba by Molmil
Crystal structure of Rtt109-Asf1-H3-H4-CoA complex
Descriptor: COENZYME A, DNA damage response protein Rtt109, putative, ...
Authors:Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
5ZBB
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BU of 5zbb by Molmil
Crystal structure of Rtt109-Asf1-H3-H4 complex
Descriptor: DI(HYDROXYETHYL)ETHER, DNA damage response protein Rtt109, putative, ...
Authors:Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
6A6Y
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BU of 6a6y by Molmil
Crystal Structure of Asf1 from Plasmodium falciparum
Descriptor: 1,2-ETHANEDIOL, Histone chaperone ASF1, putative, ...
Authors:Srivastava, D.K, Roy, S.
Deposit date:2018-06-29
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.491 Å)
Cite:Structural and Functional characterization of As1 from Plasmodium falciparum
To Be Published
6AYZ
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BU of 6ayz by Molmil
Crystal structure of Asf1-Fab 12E complex
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2017-09-08
Release date:2018-01-17
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
5UEA
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BU of 5uea by Molmil
Structure of antigen-Fab complex with Histone chaperone ASF1
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2016-12-29
Release date:2018-01-10
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
5UEK
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BU of 5uek by Molmil
Structure of antigen-Fab 12E complex with Histone chaperone ASF1
Descriptor: Fab 12E Heavy Chain, Fab 12E Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2017-01-02
Release date:2018-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
6AZ2
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BU of 6az2 by Molmil
Crystal structure of Asf1-Fab 12E complex
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2017-09-09
Release date:2018-01-10
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.477 Å)
Cite:Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
5UCB
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BU of 5ucb by Molmil
Structure of antigen-Fab complex with engineered switch residue region.
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)
Deposit date:2016-12-22
Release date:2017-12-27
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.521 Å)
Cite:Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published

 

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