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4XEK	Pyk2-FAT domain in complex with leupaxin LD4 motif Descriptor: 19-mer peptide containing Leupaxin LD4 motif, Protein-tyrosine kinase 2-beta Authors: Miller, D.J. Deposit date: 2014-12-24 Release date: 2015-12-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.793 Å) Cite: Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. Biochemistry, 55, 2016
7W8I	Crystal structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase Descriptor: Isoform 5 of Focal adhesion kinase 1, ZINC ION Authors: Momin, A.A, Sandholu, A.S, Arold, S.T. Deposit date: 2021-12-07 Release date: 2022-12-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.943 Å) Cite: Crystal structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase To Be Published
1K04	Crystal Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase Descriptor: CHLORIDE ION, FOCAL ADHESION KINASE 1 Authors: Arold, S.T, Hoellerer, M.K, Noble, M.E.M. Deposit date: 2001-09-18 Release date: 2002-01-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.95 Å) Cite: The structural basis of localization and signaling by the focal adhesion targeting domain. Structure, 10, 2002
6PW8	Hydrocarbon-Stapled Paxillin Peptide Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK) Descriptor: CHLORIDE ION, Focal adhesion kinase 1, SP3, ... Authors: Thifault, D.G, Fromme, P, Martin-Garcia, J.M. Deposit date: 2019-07-22 Release date: 2020-07-22 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Stapled Peptide Ligand Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK) To Be Published
4XEV	Fusion of Pyk2-FAT domain with Leupaxin LD1 motif, complexed with Leupaxin LD4 peptide Descriptor: 19-mer peptide containing Leupaxin LD4 motif, Fusion protein of Protein-tyrosine kinase 2-beta FAT domain and Leupaxin LD1 motif Authors: Miller, D.J. Deposit date: 2014-12-24 Release date: 2015-12-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.0073 Å) Cite: Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. Biochemistry, 55, 2016
7W8B	Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase Descriptor: Isoform 5 of Focal adhesion kinase 1 Authors: Momin, A.A, Sandholu, A.S, Arold, S.T. Deposit date: 2021-12-07 Release date: 2023-07-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.093 Å) Cite: Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase To Be Published
7W7Z	Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase Descriptor: Isoform 5 of Focal adhesion kinase 1 Authors: Momin, A.A, Sandholu, A.S, Arold, S.T. Deposit date: 2021-12-07 Release date: 2022-12-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase To Be Published
7W9U	Crystal Structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase Descriptor: Isoform 5 of Focal adhesion kinase 1, ZINC ION Authors: Momin, A.A, Sandholu, A.S, Arold, S.T. Deposit date: 2021-12-10 Release date: 2022-12-21 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.163 Å) Cite: Crystal Structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase To Be Published
1K40	crystal structure of the FAT domain of focal adhesion kinase Descriptor: adhesion kinase Authors: Hayashi, I, Vuori, K, Liddington, R.C. Deposit date: 2001-10-04 Release date: 2002-02-06 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.25 Å) Cite: The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin Nat.Struct.Biol., 9, 2002
1OW6	Paxillin LD4 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase Descriptor: Focal adhesion kinase 1, Paxillin Authors: Hoellerer, M.K, Noble, M.E.M, Labesse, G, Campbell, I.D, Werner, J.M, Arold, S.T. Deposit date: 2003-03-28 Release date: 2003-10-21 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Molecular Recognition of Paxillin LD motifs by the Focal Adhesion Targeting Domain Structure, 11, 2003
6BZ3	Complex structure of FAK FAT domain and DCC P3 motif Descriptor: CALCIUM ION, Focal adhesion kinase 1, Netrin receptor DCC Authors: Xu, S, Wang, J.-H. Deposit date: 2017-12-22 Release date: 2018-04-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.497 Å) Cite: The binding of DCC-P3 motif and FAK-FAT domain mediates the initial step of netrin-1/DCC signaling for axon attraction. Cell Discov, 4, 2018
4XEF	Pyk2-FAT complexed with Leupaxin LD motif LD1 Descriptor: 20-mer peptide containing LD1 motif of leupaxin, Protein-tyrosine kinase 2-beta Authors: Miller, D.J. Deposit date: 2014-12-23 Release date: 2015-12-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. Biochemistry, 55, 2016
3S9O	The Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase showing N-terminal interactions in cis Descriptor: CHLORIDE ION, Focal adhesion kinase 1, SODIUM ION Authors: Arold, S.T. Deposit date: 2011-06-01 Release date: 2012-06-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells. J.Biol.Chem., 290, 2015
3GM3	Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 Descriptor: Protein tyrosine kinase 2 beta Authors: Lulo, J.E, Yuzawa, S, Schlessinger, J. Deposit date: 2009-03-12 Release date: 2009-05-05 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2 Biochem.Biophys.Res.Commun., 383, 2009
1OW7	Paxillin LD4 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase Descriptor: Focal adhesion kinase 1, Paxillin Authors: Hoellerer, M.K, Noble, M.E.M, Labesse, G, Werner, J.M, Arold, S.T. Deposit date: 2003-03-28 Release date: 2003-10-21 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Molecular Recognition of Paxillin LD Motifs by the Focal Adhesion Targeting Domain Structure, 11, 2003
3GM2	Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 Descriptor: Protein tyrosine kinase 2 beta Authors: Lulo, J.E, Yuzawa, S, Schlessinger, J. Deposit date: 2009-03-12 Release date: 2009-05-05 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2 Biochem.Biophys.Res.Commun., 383, 2009
3B71	CD4 endocytosis motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase Descriptor: Focal adhesion kinase 1, T-cell surface glycoprotein CD4 Authors: Garron, M.-L, Arold, S.T. Deposit date: 2007-10-30 Release date: 2008-01-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.82 Å) Cite: Structural basis for the interaction between focal adhesion kinase and CD4. J.Mol.Biol., 375, 2008
1OW8	Paxillin LD2 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase Descriptor: Focal adhesion kinase 1, Paxillin Authors: Hoellerer, M.K, Noble, M.E.M, Labesse, G, Werner, J.M, Arold, S.T. Deposit date: 2003-03-28 Release date: 2003-10-21 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Molecular Recognition of Paxillin LD Motifs by the Focal Adhesion Targeting Domain Structure, 11, 2003
1K05	Crystal structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase Descriptor: FOCAL ADHESION KINASE 1 Authors: Arold, S.T, Hoellerer, M.K, Noble, M.E.M. Deposit date: 2001-09-18 Release date: 2002-01-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The structural basis of localization and signaling by the focal adhesion targeting domain. Structure, 10, 2002
5F28	Crystal structure of FAT domain of Focal Adhesion Kinase (FAK) bound to the transcription factor MEF2C Descriptor: Focal adhesion kinase 1, MEF2C Authors: Cardoso, A.C, Ambrosio, A.L.B, Dessen, A, Franchini, K.G. Deposit date: 2015-12-01 Release date: 2016-07-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.9 Å) Cite: FAK Forms a Complex with MEF2 to Couple Biomechanical Signaling to Transcription in Cardiomyocytes. Structure, 24, 2016
3GM1	Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 in Complex with Paxillin LD4 Motif-Derived Peptides Descriptor: Paxillin, Protein tyrosine kinase 2 beta Authors: Lulo, J.E, Yuzawa, S, Schlessinger, J. Deposit date: 2009-03-12 Release date: 2009-05-05 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2 Biochem.Biophys.Res.Commun., 383, 2009
3U3F	Structural basis for the interaction of Pyk2 PAT domain with paxillin LD motifs Descriptor: Paxillin LD2 peptide, Protein-tyrosine kinase 2-beta Authors: Vanarotti, M, Miller, D.J, Guibao, C.C, Zheng, J.J. Deposit date: 2011-10-05 Release date: 2012-10-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.101 Å) Cite: Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs. J.Mol.Biol., 426, 2014
4R32	Crystal Structure Analysis of Pyk2 and Paxillin LD motifs Descriptor: Paxillin, Protein-tyrosine kinase 2-beta Authors: Vanarotti, M, Miller, D.J, Guibao, C.D, Nourse, A, Zheng, J.J. Deposit date: 2014-08-13 Release date: 2014-09-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.505 Å) Cite: Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs. J.Mol.Biol., 426, 2014
2L6F	NMR Solution structure of FAT domain of FAK complexed with LD2 and LD4 motifs of PAXILLIN Descriptor: Focal adhesion kinase 1, linker1, Paxillin, ... Authors: Bertolucci, C.M, Guibao, C, Zhang, C, Zheng, J. Deposit date: 2010-11-19 Release date: 2012-05-30 Last modified: 2014-04-09 Method: SOLUTION NMR Cite: NMR Solution Structure of Fat Domain of Fak Complexed with Ld2 and Ld4 Motifs of Paxillin To be Published
2LK4	Structural and mechanistic insights into the interaction between PAT Pyk2 and Paxillin LD motif Descriptor: Protein-tyrosine kinase 2-beta Authors: Vanarotti, M, Miller, D, Guibao, C, Zheng, J. Deposit date: 2011-10-04 Release date: 2012-10-10 Last modified: 2014-12-31 Method: SOLUTION NMR Cite: Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs. J.Mol.Biol., 426, 2014

 

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