6PW8

Hydrocarbon-Stapled Paxillin Peptide Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK)

Summary for 6PW8

• Entry DOI: 10.2210/pdb6pw8/pdb
• Descriptor: Focal adhesion kinase 1, SP3, ZINC ION, ... (5 entities in total)
• Functional Keywords: inhibitor, stapled peptide, tyrosine kinase, protein binding-inhibitor complex, protein binding/inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 15780.30

Authors

Thifault, D.G.,Fromme, P.,Martin-Garcia, J.M. (deposition date: 2019-07-22, release date: 2020-07-22, Last modification date: 2023-11-15)

• Primary citation: Thifault, D.G.,Fromme, P.,Martin-Garcia, J.M.; Stapled Peptide Ligand Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)