6PW8

Hydrocarbon-Stapled Paxillin Peptide Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004713	molecular_function	protein tyrosine kinase activity
A	0005925	cellular_component	focal adhesion
A	0006468	biological_process	protein phosphorylation
A	0007172	biological_process	signal complex assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1101

Chain	Residue
A	GLU937
A	GLU956
A	HIS980
A	HOH1216

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site_id	AC2
Number of Residues	4
Details	binding site for residue CL A 1102

Chain	Residue
A	HIS1025
A	ASP1039
A	HOH1254
A	HOH1256

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"12387730","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19339212","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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