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6PW8

Hydrocarbon-Stapled Paxillin Peptide Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Focal adhesion kinase 1polymer12614018.41UniProt (Q05397)
Pfam (PF03623)
Homo sapiens (Human)FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK
2B
(B)
SP3polymer151661.01UniProt (by SIFTS) (P49023)Homo sapiens
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5E, F
(A, B)
waterwater18.092Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight15679.4
Non-Polymers*Number of molecules2
Total formula weight100.9
All*Total formula weight15780.3
*Water molecules are not included.

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PDB entries from 2024-10-30

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