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7ANI
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DdahB, GDP-mannoheptose C3,5 epimerase from Campylobacter jejuni
Descriptor: GLYCEROL, Thymidine diphospho-4-keto-rhamnose 3,5-epimerase
Authors:Naismith, J.H, Woodward, L.
Deposit date:2020-10-11
Release date:2020-10-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:DdahB
To Be Published
1NXM
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BU of 1nxm by Molmil
The high resolution structures of RmlC from Streptococcus suis
Descriptor: dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase
Authors:Dong, C, Major, L.L, Allen, A, Blankenfeldt, W, Maskell, D, Naismith, J.H.
Deposit date:2003-02-11
Release date:2003-06-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High-Resolution Structures of RmlC from Streptococcus suis in Complex with Substrate Analogs Locate the Active Site of This Class of Enzyme
Structure, 11, 2003
7PWI
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BU of 7pwi by Molmil
Structure of the dTDP-sugar epimerase StrM
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, dTDP-4-keto-rhamnose 3,5-epimerase,dTDP-4-dehydrorhamnose 3,5-epimerase
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-06
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.326 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
1OI6
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Structure determination of the TMP-complex of EvaD
Descriptor: GLYCEROL, PCZA361.16, THYMIDINE-5'-PHOSPHATE
Authors:Merkel, A.B, Naismith, J.H.
Deposit date:2003-06-09
Release date:2004-06-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Position of a Key Tyrosine in Dtdp-4-Keto-6-Deoxy-D-Glucose-5-Epimerase (Evad) Alters the Substrate Profile for This Rmlc-Like Enzyme
J.Biol.Chem., 279, 2004
7PVI
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BU of 7pvi by Molmil
dTDP-sugar epimerase
Descriptor: CITRATE ANION, SODIUM ION, alpha-D-xylopyranose, ...
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-04
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.434 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
8DAK
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BU of 8dak by Molmil
Crystal structure of the GDP-D-glycero-4-keto-d-lyxo-heptose-3-epimerase from Campylobacter jejuni, serotype HS:3
Descriptor: CHLORIDE ION, GDP-D-glycero-4-keto-d-lyxo-heptose-3-epimerase, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Thoden, J.B, Ghosh, M.K, Xiang, D.F, Raushel, F.M, Holden, H.M.
Deposit date:2022-06-13
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:C3- and C3/C5-Epimerases Required for the Biosynthesis of the Capsular Polysaccharides from Campylobacter jejuni .
Biochemistry, 61, 2022
1OFN
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BU of 1ofn by Molmil
Purification, crystallisation and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis; the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway.
Descriptor: GLYCEROL, PCZA361.16
Authors:Merkel, A.B, Naismith, J.H.
Deposit date:2003-04-17
Release date:2004-04-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Purification, Crystallization and Preliminary Structural Studies of Dtdp-4-Keto-6-Deoxy-Glucose-5-Epimerase (Evad) from Amycolatopsis Orientalis, the Fourth Enzyme in the Dtdp-L-Epivancosamine Biosynthetic Pathway.
Acta Crystallogr.,Sect.D, 58, 2002
1EP0
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BU of 1ep0 by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
Descriptor: DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE
Authors:Christendat, D, Saridakis, V, Bochkarev, A, Pai, E.F, Arrowsmith, C.H, Edwards, A.M, Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-03-24
Release date:2000-12-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP.
J.Biol.Chem., 275, 2000
8DCL
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BU of 8dcl by Molmil
Crystal structure of the GDP-D-glycero-4-keto-D-lyxo-heptose-3-epimerase from campylobacter jejuni, serotype HS:23/36
Descriptor: 1,2-ETHANEDIOL, GDP-D-glycero-4-keto-D-lyxo-heptose-3-epimerase, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Thoden, J.B, Ghosh, M.K, Xiang, D.F, Raushel, F.M, Holden, H.M.
Deposit date:2022-06-16
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:C3- and C3/C5-Epimerases Required for the Biosynthesis of the Capsular Polysaccharides from Campylobacter jejuni .
Biochemistry, 61, 2022
6NDR
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BU of 6ndr by Molmil
Crystal structure of dTDP-6-deoxy-D-glucose-3,5-epimerase RmlC from Legionella pneumophila Philadelphia 1 in complex with dTDP-4-KETO-L-RHAMNOSE
Descriptor: 1,2-ETHANEDIOL, DTDP-4-KETO-L-RHAMNOSE, SULFATE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-14
Release date:2018-12-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of dTDP-6-deoxy-D-glucose-3,5-epimerase RmlC from Legionella pneumophila Philadelphia 1 in complex with dTDP-4-KETO-L-RHAMNOSE
to be published
2IXL
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BU of 2ixl by Molmil
RmlC S. suis with dTDP-rhamnose
Descriptor: 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, NICKEL (II) ION
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2C0Z
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BU of 2c0z by Molmil
The 1.6 A resolution crystal structure of NovW: a 4-keto-6-deoxy sugar epimerase from the novobiocin biosynthetic gene cluster of Streptomyces spheroides
Descriptor: 1,2-ETHANEDIOL, NOVW, SULFATE ION
Authors:Jakimowicz, P, Tello, M, Freel-Meyers, C.L, Walsh, C.T, Buttner, M.J, Field, R.A, Lawson, D.M.
Deposit date:2005-09-09
Release date:2006-01-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The 1.6 A Resolution Crystal Structure of Novw: A 4-Keto-6-Deoxy Sugar Epimerase from the Novobiocin Biosynthetic Gene Cluster of Streptomyces Spheroides
Proteins, 63, 2006
1NYW
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BU of 1nyw by Molmil
The high resolution structures of RmlC from Streptoccus suis in complex with dTDP-D-glucose
Descriptor: 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase
Authors:Dong, C, Major, L.L, Allen, A, Blankenfeldt, W, Maskell, D, Naismith, J.H.
Deposit date:2003-02-14
Release date:2003-06-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-Resolution Structures of RmlC from Streptococcus suis in Complex with Substrate Analogs Locate the Active Site of This Class of Enzyme
Structure, 11, 2003
4HN1
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BU of 4hn1 by Molmil
Crystal Structure of H60N/Y130F double mutant of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP
Descriptor: 1,2-ETHANEDIOL, Putative 3-epimerase in D-allose pathway, THYMIDINE, ...
Authors:Holden, H.M, Kubiak, R.L.
Deposit date:2012-10-18
Release date:2012-11-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.
Biochemistry, 51, 2012
3RYK
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BU of 3ryk by Molmil
1.63 Angstrom resolution crystal structure of dTDP-4-dehydrorhamnose 3,5-epimerase (rfbC) from Bacillus anthracis str. Ames with TDP and PPi bound
Descriptor: PYROPHOSPHATE 2-, THYMIDINE-5'-DIPHOSPHATE, dTDP-4-dehydrorhamnose 3,5-epimerase
Authors:Halavaty, A.S, Kuhn, M, Minasov, G, Shuvalova, L, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-05-11
Release date:2011-05-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.631 Å)
Cite:Structure of the Bacillus anthracis dTDP-L-rhamnose-biosynthetic enzyme dTDP-4-dehydrorhamnose 3,5-epimerase (RfbC).
Acta Crystallogr F Struct Biol Commun, 73, 2017
2IXK
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BU of 2ixk by Molmil
RmlC P aeruginosa with dTDP-4-keto rhamnnose (the product of the reaction)
Descriptor: DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, DTDP-4-KETO-L-RHAMNOSE
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
1UPI
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BU of 1upi by Molmil
Mycobacterium tuberculosis rmlC epimerase (Rv3465)
Descriptor: DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE
Authors:Kim, C.-Y, Naranjo, C, Waldo, G.S, Lekin, T, Segelke, B.W, Kantardjieff, K.A, Zemla, A, Terwilliger, T, Rupp, B, TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-10-05
Release date:2003-10-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mycobacterium Tuberculosis Rmlc Epimerase (Rv3465): A Promising Drug-Target Structure in the Rhamnose Pathway
Acta Crystallogr.,Sect.D, 60, 2004
5BUV
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BU of 5buv by Molmil
X-ray structure of WbcA from Yersinia enterocolitica
Descriptor: 1,2-ETHANEDIOL, 6-AMINOPYRIMIDIN-2(1H)-ONE, PHOSPHATE ION, ...
Authors:Holden, H.M, Salinger, A.J, Brown, H.A, Thoden, J.B.
Deposit date:2015-06-04
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Biochemical studies on WbcA, a sugar epimerase from Yersinia enterocolitica.
Protein Sci., 24, 2015
1EPZ
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BU of 1epz by Molmil
CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOASE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM WITH BOUND LIGAND.
Descriptor: DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE, THYMIDINE-5'-DIPHOSPHATE
Authors:Christendat, D, Saridakis, V, Bochkarev, A, Pai, E.F, Arrowsmith, C, Edwards, A.M.
Deposit date:2000-03-30
Release date:2000-12-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP.
J.Biol.Chem., 275, 2000
2IXC
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BU of 2ixc by Molmil
RmlC M. tuberculosis with dTDP-rhamnose
Descriptor: 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-07
Release date:2006-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2IXI
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BU of 2ixi by Molmil
RmlC P aeruginosa with dTDP-xylose
Descriptor: DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, S,R MESO-TARTARIC ACID, THYMIDINE-5'-DIPHOSPHATE
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-07-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
1NZC
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BU of 1nzc by Molmil
The high resolution structures of RmlC from Streptococcus suis in complex with dTDP-D-xylose
Descriptor: NICKEL (II) ION, THYMIDINE-5'-DIPHOSPHO-BETA-D-XYLOSE, dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase
Authors:Dong, C, Major, L.L, Allen, A, Blankenfeldt, W, Maskell, D, Naismith, J.H.
Deposit date:2003-02-17
Release date:2003-06-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-Resolution Structures of RmlC from Streptococcus suis in Complex with Substrate Analogs Locate the Active Site of This Class of Enzyme
Structure, 11, 2003
6DIN
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BU of 6din by Molmil
High resolutionstructure of apo dTDP-4-dehydrorhamnose 3,5-epimerase
Descriptor: SULFATE ION, dTDP-4-dehydrorhamnose 3,5-epimerase
Authors:Chang, C, Jedrzejczak, R, Chhor, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-05-23
Release date:2018-05-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High resolutionstructure of apo dTDP-4-dehydrorhamnose 3,5-epimerase
To Be Published
7M15
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crystal structure of cj1430 in the presence of GDP-D-glycero-L-gluco-heptose, a GDP-D-glycero-4-keto-D-lyxo-heptose-3,5-epimerase from campylobacter jejuni
Descriptor: 1,2-ETHANEDIOL, GDP-D-glycero-L-gluco-heptose, [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4R,5R,6S)-6-[(1R)-1,2-dihydroxyethyl]-3,4,5-trihydroxyoxan-2-yl dihydrogen diphosphate (non-preferred name)
Authors:Girardi, N.M, Thoden, J.B, Raushel, F.M, Holden, H.M.
Deposit date:2021-03-12
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Biosynthesis of d- glycero -l- gluco -Heptose in the Capsular Polysaccharides of Campylobacter jejuni .
Biochemistry, 60, 2021
7PWB
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BU of 7pwb by Molmil
dTDP-sugar epimerase from Coxiella burnetii in complex with dTDP
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-06
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022

 

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