1OFN

Purification, crystallisation and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis; the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway.

Summary for 1OFN

DescriptorPCZA361.16, GLYCEROL (3 entities in total)
Functional Keywordsepimerase, vancomycin group antibiotic, evad, isomerase
Biological sourceAMYCOLATOPSIS ORIENTALIS (STREPTOMYCES)
Total number of polymer chains2
Total molecular weight45391.77
Authors
Merkel, A.B.,Naismith, J.H. (deposition date: 2003-04-17, release date: 2004-04-15, Last modification date: 2019-05-08)
Primary citation
Merkel, A.B.,Temple, G.K.,Burkart, M.D.,Losey, H.C.,Beis, K.,Walsh, C.T.,Naismith, J.H.
Purification, Crystallization and Preliminary Structural Studies of Dtdp-4-Keto-6-Deoxy-Glucose-5-Epimerase (Evad) from Amycolatopsis Orientalis, the Fourth Enzyme in the Dtdp-L-Epivancosamine Biosynthetic Pathway.
Acta Crystallogr.,Sect.D, 58:1226-, 2002
PubMed: 12077451 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444902007382
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.5 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1927 0.2% 0.6% 2.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution