6G85
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STRUCTURE OF CDC14 BOUND TO CBK1 PXL MOTIF
Descriptor:Tyrosine-protein phosphatase CDC14, CBK1, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Mouilleron, S., Kataria, M., Uhlmann, F.
Deposit date:2018-04-07
Release date:2018-10-17
Method:X-RAY DIFFRACTION (1.528 Å)
Cite:A PxL motif conveys timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase
To Be Published
6G86
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STRUCTURE OF CDC14 BOUND TO SIC1 PXL MOTIF
Descriptor:Tyrosine-protein phosphatase CDC14, Protein SIC1, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Mouilleron, S., Kataria, M., Uhlmann, F.
Deposit date:2018-04-07
Release date:2018-10-17
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:A PxL motif conveys timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase
To Be Published
6G84
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STRUCTURE OF CDC14 BOUND TO CBK1 PXL MOTIF
Descriptor:Tyrosine-protein phosphatase CDC14, CBK1, CALCIUM ION, ...
Authors:Mouilleron, S., Kataria, M., Uhlmann, F.
Deposit date:2018-04-07
Release date:2018-10-10
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:A PxL motif conveys timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase
To Be Published
6D65
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CRYSTAL STRUCTURE OF THE HUMAN DUAL SPECIFICITY PHOSPHATASE 1 CATALYTIC DOMAIN (C258S) AS A MALTOSE BINDING PROTEIN FUSION IN COMPLEX WITH THE DESIGNED AR PROTEIN OFF7
Descriptor:Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Designed AR protein off7, GLYCEROL, ...
Authors:Gumpena, R., Lountos, G.T., Waugh, D.S.
Deposit date:2018-04-20
Release date:2018-09-19
Method:X-RAY DIFFRACTION (2.348 Å)
Cite:MBP-binding DARPins facilitate the crystallization of an MBP fusion protein.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6D66
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CRYSTAL STRUCTURE OF THE HUMAN DUAL SPECIFICITY 1 CATALYTIC DOMAIN (C258S) AS A MALTOSE BINDING PROTEIN FUSION IN COMPLEX WITH THE DESIGNED AR PROTEIN MBP3_16
Descriptor:Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Designed AR protein mbp3_16, DI(HYDROXYETHYL)ETHER, ...
Authors:Gumpena, R., Waugh, D.S., Lountos, G.T.
Deposit date:2018-04-20
Release date:2018-09-19
Method:X-RAY DIFFRACTION (2.226 Å)
Cite:MBP-binding DARPins facilitate the crystallization of an MBP fusion protein.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6D67
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CRYSTAL STRUCTURE OF THE HUMAN DUAL SPECIFICITY PHOSPHATASE 1 CATALYTIC DOMAIN (C258S) AS A MALTOSE BINDING PROTEIN FUSION (MALTOSE BOUND FORM) IN COMPLEX WITH THE DESIGNED AR PROTEIN MBP3_16
Descriptor:Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Designed AR protein mbp3_16, DI(HYDROXYETHYL)ETHER, ...
Authors:Gumpena, R., Lountos, G.T., Waugh, D.S.
Deposit date:2018-04-20
Release date:2018-09-19
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:MBP-binding DARPins facilitate the crystallization of an MBP fusion protein.
Acta Crystallogr F Struct Biol Commun, 74, 2018
5Z5A
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CRYSTAL STRUCTURE OF TK-PTP IN THE ACTIVE FORM
Descriptor:Protein-tyrosine phosphatase, VANADATE ION
Authors:Ku, B., Yun, H.Y., Kim, S.J.
Deposit date:2018-01-17
Release date:2018-07-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1
PLoS ONE, 13, 2018
5Z59
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CRYSTAL STRUCTURE OF TK-PTP IN THE INACTIVE FORM
Descriptor:Protein-tyrosine phosphatase
Authors:Ku, B., Yun, H.Y., Kim, S.J.
Deposit date:2018-01-17
Release date:2018-06-27
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1
PLoS ONE, 13, 2018
5Z5B
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CRYSTAL STRUCTURE OF TK-PTP IN THE G95A MUTANT FORM
Descriptor:Protein-tyrosine phosphatase, CHLORIDE ION, FORMIC ACID
Authors:Ku, B., Yun, H.Y., Kim, S.J.
Deposit date:2018-01-17
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1
PLoS ONE, 13, 2018
5XJV
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TWO INTERMEDIATE STATES OF CONFORMATION SWITCH IN DUAL SPECIFICITY PHOSPHATASE 13A
Descriptor:Dual specificity protein phosphatase 13 isoform A, PHOSPHATE ION
Authors:Wei, C.H., Min, H.G., Chun, H.J., Ryu, S.E.
Deposit date:2017-05-04
Release date:2018-04-11
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Two intermediate states of the conformational switch in dual specificity phosphatase 13a
Pharmacol. Res., 128, 2018
5Y15
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CRYSTAL STRUCTURE OF HUMAN DUSP28
Descriptor:Dual specificity phosphatase 28, PHOSPHATE ION
Authors:Ku, B., Hong, W., Kim, S.J., Ryu, S.E.
Deposit date:2017-07-19
Release date:2017-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28
PLoS ONE, 12, 2017
5Y16
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CRYSTAL STRUCTURE OF HUMAN DUSP28(Y102H)
Descriptor:Dual specificity phosphatase 28, PHOSPHATE ION, CHLORIDE ION
Authors:Ku, B., Kim, M., Kim, S.J., Ryu, S.E.
Deposit date:2017-07-19
Release date:2017-11-22
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28
PLoS ONE, 12, 2017
6APX
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CRYSTAL STRUCTURE OF HUMAN DUAL SPECIFICITY PHOSPHATASE 1 CATALYTIC DOMAIN (C258S) AS A MALTOSE BINDING PROTEIN FUSION IN COMPLEX WITH THE MONOBODY YSX1
Descriptor:Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Monobody YSX1, SULFATE ION, ...
Authors:Gumpena, R., Lountos, G.T., Sreejith, R.K., Tropea, J.E., Cherry, S., Waugh, D.S.
Deposit date:2017-08-18
Release date:2017-11-01
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.491 Å)
Cite:Crystal structure of the human dual specificity phosphatase 1 catalytic domain.
Protein Sci., 27, 2018
5NCR
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OH1 FROM THE ORF VIRUS: A TYROSINE PHOSPHATASE THAT DISPLAYS DISTINCT STRUCTURAL FEATURES AND TRIPLE SUBSTRATE SPECIFICITY
Descriptor:tyrosine phosphatase, PHOSPHATE ION, SULFATE ION
Authors:Segovia, D., Haouz, A., Berois, M., Villarino, A., Andre-Leroux, G.
Deposit date:2017-03-06
Release date:2017-08-09
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity.
J. Mol. Biol., 429, 2017
5XW4
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CRYSTAL STRUCTURE OF BUDDING YEAST CDC14P (WILD TYPE) IN THE APO STATE
Descriptor:Tyrosine-protein phosphatase CDC14
Authors:Kobayashi, J., Matsuura, Y.
Deposit date:2017-06-29
Release date:2017-08-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and dimerization of the catalytic domain of the protein phosphatase Cdc14p, a key regulator of mitotic exit in Saccharomyces cerevisiae
Protein Sci., 26, 2017
5XW5
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CRYSTAL STRUCTURE OF BUDDING YEAST CDC14P (C283S) BOUND TO A SWI6P PHOSPHOPEPTIDE
Descriptor:Tyrosine-protein phosphatase CDC14, Regulatory protein SWI6, SULFATE ION
Authors:Kobayashi, J., Matsuura, Y.
Deposit date:2017-06-29
Release date:2017-08-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and dimerization of the catalytic domain of the protein phosphatase Cdc14p, a key regulator of mitotic exit in Saccharomyces cerevisiae
Protein Sci., 26, 2017
5TSR
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CRYSTAL STRUCTURE OF PRL-3 PHOSPHATASE IN COMPLEX WITH THE BATEMAN DOMAIN OF CNNM3 MAGNESIUM TRANSPORTER
Descriptor:Protein tyrosine phosphatase type IVA 3, Metal transporter CNNM3
Authors:Kozlov, G., Zhang, H., Gehring, K.
Deposit date:2016-10-31
Release date:2017-02-08
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.188 Å)
Cite:PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.
Sci Rep, 7, 2017
5BX1
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CRYSTAL STRUCTURE OF PRL-1 COMPLEX WITH COMPOUND ANALOGY 3
Descriptor:Protein tyrosine phosphatase type IVA 1, 3-(5,6-dimethyl-2H-isoindol-2-yl)-N'-[(E)-furan-2-ylmethylidene]benzohydrazide, SULFATE ION
Authors:Liu, S., Bai, Y., Zhang, Z.
Deposit date:2015-06-08
Release date:2016-12-21
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of PRL-1 complex with compound analogy 3
To Be Published
5MMZ
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STRUCTURE OF PRL-1 IN COMPLEX WITH THE BATEMAN DOMAIN OF CNNM2
Descriptor:Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1
Authors:Gimenez-Mascarell, P., Oyenarte, I., Hardy, S., Breiderhoff, T., Stuiver, M., Kostantin, E., Diercks, T., Pey, A.L., Ereno-Orbea, J., Martinez-Chantar, M.L., Khalaf-Nazzal, R., Claverie-Martin, F., Muller, D., Tremblay, M.L., Martinez-Cruz, L.A.
Deposit date:2016-12-12
Release date:2016-12-21
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
5LXQ
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STRUCTURE OF PRL-1 IN COMPLEX WITH THE BATEMAN DOMAIN OF CNNM2
Descriptor:Protein tyrosine phosphatase type IVA 1, Metal transporter CNNM2, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:GIMENEZ-Mascarell, P., Oyenarte, I., HARDY, S., Breiderhoff, T., STUIVER, M., Kostantin, E., Diercks, T., Pey, A.L., Ereno-ORBEA, J., Martinez-Chantar, M.L., Khalaf-Nazzal, R., Claverie-Martin, F., MULLER, D., TREMBLAY, M., Martinez-Cruz, L.A.
Deposit date:2016-09-22
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (3.335 Å)
Cite:Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
5M43
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CRYSTAL STRUCTURE OF YVH1 PHOSPHATASE DOMAIN FROM CHAETOMIUM THERMOPHILUM
Descriptor:Putative uncharacterized protein, NITRATE ION, GLYCEROL
Authors:Ahmed, Y.L., Sinning, I.
Deposit date:2016-10-18
Release date:2016-11-30
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.646 Å)
Cite:Interaction network of the ribosome assembly machinery from a eukaryotic thermophile.
Protein Sci., 26, 2017
5GTJ
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CRYSTAL STRUCTURE OF CATALYTICALLY ACTIVE FORM OF HUMAN DUSP26
Descriptor:Dual specificity protein phosphatase 26, PHOSPHATE ION
Authors:Won, E.-Y., Kim, S.J., Chi, S.-W.
Deposit date:2016-08-21
Release date:2016-09-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insight into the Critical Role of the N-Terminal Region in the Catalytic Activity of Dual-Specificity Phosphatase 26
Plos One, 11, 2016
4YR8
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CRYSTAL STRUCTURE OF JNK IN COMPLEX WITH A REGULATOR PROTEIN
Descriptor:Mitogen-activated protein kinase 8, Dual specificity protein phosphatase 16, CHLORIDE ION
Authors:Liu, X., Wang, J., Wu, J.W., Wang, Z.X.
Deposit date:2015-03-14
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation.
Nat Commun, 7, 2016
4D3P
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CRYSTAL STRUCTURE OF POINT MUTATED DUSP19 (C150A)
Descriptor:DUAL SPECIFICITY PROTEIN PHOSPHATASE 19, SULFATE ION
Authors:Jeon, T.J., Nam, K.T., Ryu, S.E.
Deposit date:2014-10-23
Release date:2015-11-04
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Structural Analysis of Activity-Modulating Mutations of Dusp19
Biodesign, 3, 2015
4D3Q
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CRYSTAL STRUCTURE OF POINT MUTATED DUSP19 (R156A)
Descriptor:DUAL SPECIFICITY PROTEIN PHOSPHATASE 19, SULFATE ION
Authors:Jeon, T.J., Nam, K.T., Ryu, S.E.
Deposit date:2014-10-23
Release date:2015-11-04
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural Analysis of Activity-Modulating Mutations of Dusp19
Biodesign, 3, 2015
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