8TK6
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) in apo form
Summary for 8TK6
Entry DOI | 10.2210/pdb8tk6/pdb |
Descriptor | Dual specificity protein phosphatase 3 (2 entities in total) |
Functional Keywords | protein dual-specificity phosphatase, vhr, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 40566.00 |
Authors | Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. (deposition date: 2023-07-25, release date: 2024-08-14) |
Primary citation | Wu, J.,Baranowski, M.R.,Aleshin, A.E.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. Fragment Screening Platform and Discovery of Novel Fragment Binders of the VHR Phosphatase, a Drug Target for Sepsis and Septic Shock To Be Published, |
Experimental method |
Structure validation
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