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8TK6

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) in apo form

Summary for 8TK6
Entry DOI10.2210/pdb8tk6/pdb
DescriptorDual specificity protein phosphatase 3 (2 entities in total)
Functional Keywordsprotein dual-specificity phosphatase, vhr, hydrolase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight40566.00
Authors
Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. (deposition date: 2023-07-25, release date: 2024-08-14)
Primary citationWu, J.,Baranowski, M.R.,Aleshin, A.E.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L.
Fragment Screening Platform and Discovery of Novel Fragment Binders of the VHR Phosphatase, a Drug Target for Sepsis and Septic Shock
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation

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PDB entries from 2024-11-13

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