1C15
| SOLUTION STRUCTURE OF APAF-1 CARD | Descriptor: | APOPTOTIC PROTEASE ACTIVATING FACTOR 1 | Authors: | Zhou, P, Chou, J, Olea, R.S, Yuan, J, Wagner, G. | Deposit date: | 1999-07-20 | Release date: | 1999-09-20 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction. Proc.Natl.Acad.Sci.USA, 96, 1999
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1CWW
| SOLUTION STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN (CARD) FROM APAF-1 | Descriptor: | APOPTOTIC PROTEASE ACTIVATING FACTOR 1 | Authors: | Day, C.L, Dupont, C, Lackmann, M, Vaux, D.L, Hinds, M.G. | Deposit date: | 1999-08-26 | Release date: | 2000-01-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1. Cell Death Differ., 6, 1999
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1CY5
| CRYSTAL STRUCTURE OF THE APAF-1 CARD | Descriptor: | BETA-MERCAPTOETHANOL, PROTEIN (APOPTOTIC PROTEASE ACTIVATING FACTOR 1), ZINC ION | Authors: | Vaughn, D.E, Joshua-Tor, L. | Deposit date: | 1999-08-31 | Release date: | 1999-09-13 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling. J.Mol.Biol., 293, 1999
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1DGN
| SOLUTION STRUCTURE OF ICEBERG, AN INHIBITOR OF INTERLEUKIN-1BETA GENERATION | Descriptor: | ICEBERG (PROTEASE INHIBITOR) | Authors: | Humke, E.W, Shriver, S.K, Starovasnik, M.A, Fairbrother, W.J, Dixit, V.M. | Deposit date: | 1999-11-24 | Release date: | 2000-10-09 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | ICEBERG: a novel inhibitor of interleukin-1beta generation. Cell(Cambridge,Mass.), 103, 2000
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1Z6T
| Structure of the apoptotic protease-activating factor 1 bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Apoptotic protease activating factor 1 | Authors: | Riedl, S.J, Li, W, Chao, Y, Schwarzenbacher, R, Shi, Y. | Deposit date: | 2005-03-23 | Release date: | 2005-04-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure of the apoptotic protease-activating factor 1 bound to ADP Nature, 434, 2005
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2A5Y
| Structure of a CED-4/CED-9 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Apoptosis regulator ced-9, MAGNESIUM ION, ... | Authors: | Yan, N, Liu, Q, Hao, Q, Gu, L, Shi, Y. | Deposit date: | 2005-07-01 | Release date: | 2005-10-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature, 437, 2005
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2B1W
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2DBD
| Solution structure of the CARD domain in human caspase recruitment domain protein 4 (Nod1 protein) | Descriptor: | Caspase recruitment domain protein 4 | Authors: | Saito, K, Inoue, M, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-12-15 | Release date: | 2006-12-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the CARD domain in human caspase recruitment domain protein 4 (Nod1 protein) To be Published
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2KN6
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2L9M
| Structure of cIAP1 CARD | Descriptor: | Baculoviral IAP repeat-containing protein 2 | Authors: | Day, C.L, Rautureau, G.J.P, Hinds, M.G. | Deposit date: | 2011-02-21 | Release date: | 2011-08-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration. Mol.Cell, 42, 2011
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2MB9
| Human Bcl10 CARD | Descriptor: | B-cell lymphoma/leukemia 10 | Authors: | Zheng, C, Bracken, C, Wu, H. | Deposit date: | 2013-07-26 | Release date: | 2013-10-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly. Mol.Cell, 51, 2013
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2N7Z
| Solution structure of RIP2 CARD | Descriptor: | Receptor-interacting serine/threonine-protein kinase 2 | Authors: | Lin, Z, Ibanez, C.F. | Deposit date: | 2015-09-28 | Release date: | 2015-12-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis of death domain signaling in the p75 neurotrophin receptor Elife, 4, 2015
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2N83
| p75NTR DD:RIP2 CARD | Descriptor: | Receptor-interacting serine/threonine-protein kinase 2, Tumor necrosis factor receptor superfamily member 16 | Authors: | Lin, Z, Ibanez, C.F. | Deposit date: | 2015-10-02 | Release date: | 2015-12-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis of death domain signaling in the p75 neurotrophin receptor Elife, 4, 2015
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2NSN
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2NZ7
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2P1H
| Rapid Folding and Unfolding of Apaf-1 CARD | Descriptor: | Apoptotic protease-activating factor 1, ZINC ION | Authors: | Milam, S.L, Nicely, N.I, Feeney, B, Mattos, C, Clark, A.C. | Deposit date: | 2007-03-05 | Release date: | 2007-05-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Rapid Folding and Unfolding of Apaf-1 CARD. J.Mol.Biol., 369, 2007
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2YGS
| CARD DOMAIN FROM APAF-1 | Descriptor: | APOPTOTIC PROTEASE ACTIVATING FACTOR 1 | Authors: | Shi, Y. | Deposit date: | 1999-05-08 | Release date: | 2000-04-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature, 399, 1999
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3CRD
| NMR STRUCTURE OF THE RAIDD CARD DOMAIN, 15 STRUCTURES | Descriptor: | RAIDD | Authors: | Chou, J.J, Matsuo, H, Duan, H, Wagner, G. | Deposit date: | 1998-07-24 | Release date: | 1999-02-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment. Cell(Cambridge,Mass.), 94, 1998
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3J2T
| An improved model of the human apoptosome | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ... | Authors: | Yuan, S, Topf, M, Akey, C.W. | Deposit date: | 2012-12-23 | Release date: | 2013-04-10 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Changes in apaf-1 conformation that drive apoptosome assembly. Biochemistry, 52, 2013
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3JBT
| Atomic structure of the Apaf-1 apoptosome | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ... | Authors: | Zhou, M, Li, Y, Hu, Q, Bai, X, Huang, W, Yan, C, Scheres, S.H.W, Shi, Y. | Deposit date: | 2015-10-15 | Release date: | 2015-11-18 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1 Genes Dev., 29, 2015
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3KAT
| Crystal Structure of the CARD domain of the human NLRP1 protein, Northeast Structural Genomics Consortium Target HR3486E | Descriptor: | NACHT, LRR and PYD domains-containing protein 1 | Authors: | Forouhar, F, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-10-19 | Release date: | 2009-10-27 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Northeast Structural Genomics Consortium Target HR3486E To be Published
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3LQQ
| Structure of the CED-4 Apoptosome | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell death protein 4, MAGNESIUM ION | Authors: | Qi, S, Pang, Y, Shi, Y, Yan, N, Liu, Q. | Deposit date: | 2010-02-09 | Release date: | 2010-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.534 Å) | Cite: | Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4. Cell(Cambridge,Mass.), 141, 2010
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3LQR
| Structure of CED-4:CED-3 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell death protein 4, MAGNESIUM ION | Authors: | Qi, S, Pang, Y, Shi, Y, Yan, N. | Deposit date: | 2010-02-09 | Release date: | 2010-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.896 Å) | Cite: | Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4. Cell(Cambridge,Mass.), 141, 2010
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3SFZ
| Crystal structure of full-length murine Apaf-1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Apoptotic peptidase activating factor 1, GAMMA-BUTYROLACTONE | Authors: | Eschenburg, S, Reubold, T.F. | Deposit date: | 2011-06-14 | Release date: | 2011-08-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of full-length Apaf-1: how the death signal is relayed in the mitochondrial pathway of apoptosis. Structure, 19, 2011
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3SHF
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