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6LUJ
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Crystal structure of the SAMD1 SAM domain
Descriptor: Atherin, SULFATE ION
Authors:Cao, Y, Zhou, Y, Wang, Z.
Deposit date:2020-01-29
Release date:2021-02-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
Sci Adv, 7, 2021
5ZRY
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BU of 5zry by Molmil
Crystal Structure of EphA6/Odin Complex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ...
Authors:Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
8UCY
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BU of 8ucy by Molmil
Sterile Alpha Motif (SAM) domain from Tric1, Arabidopsis thaliana
Descriptor: CHLORIDE ION, Chloroplastic import inner membrane translocase subunit HP30-1
Authors:Olasz, B, Vrielink, A, Evans, G.L.
Deposit date:2023-09-27
Release date:2024-05-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural analysis of the SAM domain of the Arabidopsis mitochondrial tRNA import receptor.
J.Biol.Chem., 300, 2024
5ZRX
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BU of 5zrx by Molmil
Crystal Structure of EphA2/SHIP2 Complex
Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2
Authors:Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
4NL9
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BU of 4nl9 by Molmil
Crystal structure of the human Anks3-SAM/Anks6-SAM heterodimer
Descriptor: Ankyrin repeat and SAM domain-containing protein 3, Ankyrin repeat and SAM domain-containing protein 6, MAGNESIUM ION
Authors:Leettola, C.N, Cascio, D, Bowie, J.U.
Deposit date:2013-11-13
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3.
Bmc Struct.Biol., 14, 2014
4NJ8
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Crystal structure of the human ANKS3 SAM Domain L52A mutant
Descriptor: Ankyrin repeat and SAM domain-containing protein 3
Authors:Leettola, C.N, Cascio, D, Bowie, J.U.
Deposit date:2013-11-08
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3.
Bmc Struct.Biol., 14, 2014
8J1I
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BU of 8j1i by Molmil
Crystal Structure of EphA8/SASH1 Complex
Descriptor: Ephrin type-A receptor 8, SAM and SH3 domain-containing protein 1
Authors:Liu, W, Li, J, Ding, Y.
Deposit date:2023-04-12
Release date:2024-02-28
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:SASH1: A Novel Eph Receptor Partner and Insights into SAM-SAM Interactions.
J.Mol.Biol., 435, 2023
7KJA
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BU of 7kja by Molmil
Crystal structure of the EphA2 intracellular KD-SAM domains
Descriptor: Ephrin type-A receptor 2, GLYCEROL, MAGNESIUM ION, ...
Authors:Lechtenberg, B.C, Pasquale, E.B.
Deposit date:2020-10-26
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker.
Nat Commun, 12, 2021
4RQM
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BU of 4rqm by Molmil
Crystal structure of the SeMET BICC1 SAM Domain R924E mutant
Descriptor: Protein bicaudal C homolog 1, ZINC ION
Authors:Leettola, C.N, Cascio, D, Bowie, J.U.
Deposit date:2014-11-03
Release date:2016-01-27
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6.
Structure, 26, 2018
1PK1
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Hetero SAM domain structure of Ph and Scm.
Descriptor: Polyhomeotic-proximal chromatin protein, Sex comb on midleg CG9495-PA
Authors:Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U.
Deposit date:2003-06-04
Release date:2005-02-15
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
1OXJ
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BU of 1oxj by Molmil
Crystal structure of the Smaug RNA binding domain
Descriptor: RNA-binding protein Smaug
Authors:Green, J.B, Gardner, C.D, Wharton, R.P, Aggarwal, A.K.
Deposit date:2003-04-02
Release date:2003-07-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:RNA recognition via the SAM domain of Smaug.
Mol.Cell, 11, 2003
1PK3
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BU of 1pk3 by Molmil
Scm SAM domain
Descriptor: BETA-MERCAPTOETHANOL, Sex comb on midleg CG9495-PA
Authors:Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U.
Deposit date:2003-06-04
Release date:2005-02-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
8UD0
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BU of 8ud0 by Molmil
Sterile Alpha Motif (SAM) domain from Tric1 from Arabidopsis thaliana - G241E mutant
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Chloroplastic import inner membrane translocase subunit HP30-1
Authors:Olasz, B, Vrielink, A, Smithers, L.
Deposit date:2023-09-27
Release date:2024-05-01
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural analysis of the SAM domain of the Arabidopsis mitochondrial tRNA import receptor.
J.Biol.Chem., 300, 2024
5ZRZ
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BU of 5zrz by Molmil
Crystal Structure of EphA5/SAMD5 Complex
Descriptor: Ephrin type-A receptor 5, Sterile alpha motif domain-containing protein 5
Authors:Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
6KIP
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BU of 6kip by Molmil
Crystal structure of PTPRD phosphatase domain in complex with Liprin-alpha3 tandem SAM domains
Descriptor: Liprin-alpha-3, Receptor-type tyrosine-protein phosphatase delta
Authors:Wakita, M, Yamagata, A, Fukai, S.
Deposit date:2019-07-19
Release date:2020-02-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.911 Å)
Cite:Structural insights into selective interaction between type IIa receptor protein tyrosine phosphatases and Liprin-alpha.
Nat Commun, 11, 2020
1B4F
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BU of 1b4f by Molmil
OLIGOMERIC STRUCTURE OF THE HUMAN EPHB2 RECEPTOR SAM DOMAIN
Descriptor: EPHB2
Authors:Thanos, C.D, Goodwill, K.E, Bowie, J.U.
Deposit date:1998-12-20
Release date:1999-02-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Oligomeric structure of the human EphB2 receptor SAM domain.
Science, 283, 1999
8B10
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BU of 8b10 by Molmil
Crystal Structure of Shank2-SAM mutant domain - L1800W
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Bento, I, Gracia Alai, M, Kreienkamp, J.-H.
Deposit date:2022-09-08
Release date:2022-11-30
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans.
Mol Psychiatry, 29, 2024
5J8Y
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BU of 5j8y by Molmil
Crystal structure of the Scm-SAM and Sfmbt-SAM heterodimer
Descriptor: Polycomb protein Scm, Polycomb protein Sfmbt
Authors:Frey, F, Benda, C, Mueller, J.
Deposit date:2016-04-08
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC.
Genes Dev., 30, 2016
3BS5
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BU of 3bs5 by Molmil
Crystal Structure of hCNK2-SAM/dHYP-SAM Complex
Descriptor: Connector enhancer of kinase suppressor of ras 2, Protein aveugle
Authors:Rajakulendran, T, Ceccarelli, D.F, Kurinov, I, Sicheri, F.
Deposit date:2007-12-22
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.
Proc.Natl.Acad.Sci.USA, 105, 2008
3HIL
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BU of 3hil by Molmil
SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1)
Descriptor: CHLORIDE ION, Ephrin type-A receptor 1, NITRATE ION
Authors:Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-05-20
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1).
To be Published
4RQN
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BU of 4rqn by Molmil
Crystal structure of the native BICC1 SAM Domain R924E mutant
Descriptor: Protein bicaudal C homolog 1, ZINC ION
Authors:Leettola, C.N, Cascio, D, Bowie, J.U.
Deposit date:2014-11-03
Release date:2016-01-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6.
Structure, 26, 2018
6FXF
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BU of 6fxf by Molmil
Crystal structure of the SAM domain of murine SLy1
Descriptor: SAM and SH3 domain-containing protein 3
Authors:Kukuk, L.K, Granzin, J, Batra-Safferling, R, Koenig, B.W.
Deposit date:2018-03-09
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association.
Sci Rep, 9, 2019
6LUK
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BU of 6luk by Molmil
Crystal structure of the SAMD1 SAM domain in another crystal form
Descriptor: Atherin, SULFATE ION
Authors:Cao, Y, Zhou, Y, Wang, Z.
Deposit date:2020-01-29
Release date:2021-02-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
Sci Adv, 7, 2021
8UCZ
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BU of 8ucz by Molmil
Sterile Alpha Motif (SAM) domain from Tric1 from Arabidopsis thaliana - D235A mutant
Descriptor: CHLORIDE ION, Chloroplastic import inner membrane translocase subunit HP30-1
Authors:Olasz, B, Vrielink, A, Smithers, L.
Deposit date:2023-09-27
Release date:2024-05-01
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural analysis of the SAM domain of the Arabidopsis mitochondrial tRNA import receptor.
J.Biol.Chem., 300, 2024
8BW8
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BU of 8bw8 by Molmil
Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex
Descriptor: Connector enhancer of KSR protein CNK, GLYCEROL, Protein aveugle
Authors:Maisonneuve, P, Kurinov, I, Sicheri, F.
Deposit date:2022-12-06
Release date:2024-02-21
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction.
Nat.Struct.Mol.Biol., 31, 2024

 

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