4RQM

Crystal structure of the SeMET BICC1 SAM Domain R924E mutant

Summary for 4RQM

• Entry DOI: 10.2210/pdb4rqm/pdb
• Related: 4RQN
• Descriptor: Protein bicaudal C homolog 1, ZINC ION (3 entities in total)
• Functional Keywords: sam domain, protein-protein interaction domain, polymerization domain, polymerization, p-bodies, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 24440.60

Authors

Leettola, C.N.,Cascio, D.,Bowie, J.U. (deposition date: 2014-11-03, release date: 2016-01-27, Last modification date: 2019-10-23)

• Primary citation: Rothe, B.,Leettola, C.N.,Leal-Esteban, L.,Cascio, D.,Fortier, S.,Isenschmid, M.,Bowie, J.U.,Constam, D.B.; Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6.; Structure, 26:209-224.e6, 2018; PubMed: 29290488; DOI: 10.1016/j.str.2017.12.002

Experimental method

X-RAY DIFFRACTION (1.75 Å)