5MHB
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PRODUCT-COMPLEX OF E.COLI 5-AMINO LAEVULINIC ACID DEHYDRATASE
Descriptor:Delta-aminolevulinic acid dehydratase, 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, ZINC ION, ...
Authors:Norton, E., Erskine, P.T., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2016-11-23
Release date:2016-12-07
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5LZL
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PYROBACULUM CALIDIFONTIS 5-AMINOLAEVULINIC ACID DEHYDRATASE
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION
Authors:Azim, N., Erskine, P.T., Guo, J., Cooper, J.B.
Deposit date:2016-09-30
Release date:2016-10-12
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5HMS
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X-RAY STRUCTURE OF HUMAN RECOMBINANT 5-AMINOLAEVULINIC ACID DEHYDRATASE (HRALAD).
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION
Authors:Butler, D., Erskine, P.T., Cooper, J.B., Shoolingin-Jordan, P.M.
Deposit date:2016-01-17
Release date:2016-01-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5HNR
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THE X-RAY STRUCTURE OF OCTAMERIC HUMAN NATIVE 5-AMINOLAEVULINIC ACID DEHYDRATASE.
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION, SULFATE ION, ...
Authors:Mills-Davies, N.L., Thompson, D., Shoolingin-Jordan, P.M., Erskine, P.T., Cooper, J.B.
Deposit date:2016-01-18
Release date:2016-01-27
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
2WOQ
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PORPHOBILINOGEN SYNTHASE (HEMB) IN COMPLEX WITH 5-ACETAMIDO-4- OXOHEXANOIC ACID (ALAREMYCIN 2)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ALAREMYCIN 2, MAGNESIUM ION, ...
Authors:Heinemann, I.U., Schulz, C., Schubert, W.-D., Heinz, D.W., Wang, Y.-G., Kobayashi, Y., Awa, Y., Wachi, M., Jahn, D., Jahn, M.
Deposit date:2009-07-27
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of the Heme Biosynthetic Pseudomonas Aeruginosa Porphobilinogen Synthase in Complex with the Antibiotic Alaremycin.
Antimicrob.Agents Chemother., 54, 2010
2Z0I
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CRYSTAL STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE (ALAD) FROM MUS MUSCULUS
Descriptor:Delta-aminolevulinic acid dehydratase
Authors:Wang, H., Xie, Y., Kawazoe, M., Kishishita, S., Murayama, K., Takemoto, C., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-07
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculus
To be Published
2Z1B
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CRYSTAL STRUCTURE OF 5-AMINOLEVULINIC ACID DEHYDRATASE (ALAD) FROM MUS MUSCULS
Descriptor:Delta-aminolevulinic acid dehydratase
Authors:Xie, Y., Wang, H., Kawazoe, M., Kishishita, S., Murayama, K., Takemoto, C., Terada, T., Shirozu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-08
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs
To be Published
2C13
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5-HYDROXY-LEVULINIC ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C14
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5-(4-CARBOXY-2-OXO-BUTYLAMINO)-4-OXO-PENTANOIC ACID ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C15
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5-(4-CARBOXY-2-OXO-BUTOXY)-4-OXO-PENTANOIC ACID ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C16
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5-(4-CARBOXY-2-OXO-BUTANE-1-SULFINYL)-4-OXO-PENTANOIC ACID ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, TRIETHYLENE GLYCOL, ...
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C18
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5-(4-CARBOXY-2-OXO-BUTANE-1-SULFONYL)-4-OXO-PENTANOIC ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, SODIUM ION, ...
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C19
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5-(4-CARBOXY-2-OXO-BUTYLSULFANYL)-4-OXO-PENTANOIC ACID ACID BOUND TO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, SODIUM ION
Authors:Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R., Frankenberg-Dinkel, N.
Deposit date:2005-09-11
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45, 2006
2C1H
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THE X-RAY STRUCTURE OF CHLOROBIUM VIBRIOFORME 5-AMINOLAEVULINIC ACID DEHYDRATASE COMPLEXED WITH A DIACID INHIBITOR
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, 4,7-DIOXOSEBACIC ACID
Authors:Coates, L., Beaven, G., Erskine, P.T., Beale, S., Wood, S.P., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2005-09-14
Release date:2005-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Chlorobium Vibrioforme 5-Aminolaevulinic Acid Dehydratase Complexed with a Diacid Inhibitor.
Acta Crystallogr.,Sect.D, 61, 2005
1W31
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 5-HYDROXYLAEVULINIC ACID COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, 5-HYDROXYLAEVULINIC ACID, ZINC ION
Authors:Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Beaven, G.D.E., Gill, R., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
Deposit date:2004-07-11
Release date:2005-08-23
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with the Inhibitor 5-Hydroxylaevulinic Acid
Acta Crystallogr.,Sect.D, 61, 2005
1W54
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STEPWISE INTRODUCTION OF A ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE FROM PSEUDOMONAS AERUGINOSA (MUTATION D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, POTASSIUM ION, ...
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-05
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W56
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C AND D131C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, MAGNESIUM ION, ...
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-05
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5M
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C AND D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, CHLORIDE ION, FORMIC ACID, ...
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5N
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS D131C AND D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, CHLORIDE ION, ...
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5O
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C, D131C AND D139C)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, GLYCEROL, POTASSIUM ION, ...
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5P
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C, D131C, D139C, P132E)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, 1,2-ETHANEDIOL, FORMIC ACID, ...
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W5Q
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STEPWISE INTRODUCTION OF ZINC BINDING SITE INTO PORPHOBILINOGEN SYNTHASE OF PSEUDOMONAS AERUGINOSA (MUTATIONS A129C, D131C, D139C, P132E, K229R)
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, FORMIC ACID, MAGNESIUM ION, ...
Authors:Frere, F., Reents, H., Schubert, W.-D., Heinz, D.W., Jahn, D.
Deposit date:2004-08-09
Release date:2005-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro
J.Mol.Biol., 345, 2005
1W1Z
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STRUCTURE OF THE PLANT LIKE 5-AMINOLAEVULINIC ACID DEHYDRATASE FROM CHLOROBIUM VIBRIOFORME
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, LAEVULINIC ACID, MAGNESIUM ION
Authors:Coates, L., Beaven, G., Erskine, P.T., Beale, S.I., Avissar, Y.J., Gill, R., Mohammed, F., Wood, S.P., Shoolingin-Jordan, P., Cooper, J.B.
Deposit date:2004-06-24
Release date:2004-09-02
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The X-ray structure of the plant like 5-aminolaevulinic acid dehydratase from Chlorobium vibrioforme complexed with the inhibitor laevulinic acid at 2.6 A resolution.
J. Mol. Biol., 342, 2004
1PV8
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CRYSTAL STRUCTURE OF A LOW ACTIVITY F12L MUTANT OF HUMAN PORPHOBILINOGEN SYNTHASE
Descriptor:Delta-aminolevulinic acid dehydratase, ZINC ION, 3-(2-AMINOETHYL)-4-(AMINOMETHYL)HEPTANEDIOIC ACID
Authors:Breinig, S., Kervinen, J., Stith, L., Wasson, A.S., Fairman, R., Wlodawer, A., Zdanov, A., Jaffe, E.K.
Deposit date:2003-06-26
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase.
Nat.Struct.Biol., 10, 2003
1OHL
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE PUTATIVE CYCLIC REACTION INTERMEDIATE COMPLEX
Descriptor:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ZINC ION, BETA-MERCAPTOETHANOL, ...
Authors:Erskine, P.T., Coates, L., Butler, D., Youell, J.H., Brindley, A.A., Wood, S.P., Warren, M.J., Shoolingin-Jordan, P.M., Cooper, J.B.
Deposit date:2003-05-27
Release date:2003-06-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-Ray Structure of a Putative Reaction Intermediateof 5-Aminolaevulinic Acid Dehydratase
Biochem.J., 373, 2003
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