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2C18

5-(4-Carboxy-2-oxo-butane-1-sulfonyl)-4-oxo-pentanoic acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa

Summary for 2C18
Entry DOI10.2210/pdb2c18/pdb
Related1B4K 1GZG 1W54 1W56 1W5M 1W5N 1W5O 1W5P 1W5Q 2C13 2C14 2C15 2C16 2C19
DescriptorDELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, SODIUM ION, ... (6 entities in total)
Functional Keywordsenzyme mechanism, metalloenzyme, porphobilinogen synthase, cocrystallization, lyase, porphyrin biosynthesis
Biological sourcePSEUDOMONAS AERUGINOSA
Total number of polymer chains2
Total formula weight75265.67
Authors
Frere, F.,Nentwich, M.,Gacond, S.,Heinz, D.W.,Neier, R.,Frankenberg-Dinkel, N. (deposition date: 2005-09-11, release date: 2006-06-20, Last modification date: 2023-12-13)
Primary citationFrere, F.,Nentwich, M.,Gacond, S.,Heinz, D.W.,Neier, R.,Frankenberg-Dinkel, N.
Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors.
Biochemistry, 45:8243-, 2006
Cited by
PubMed: 16819823
DOI: 10.1021/BI052611F
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.93 Å)
Structure validation

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