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6HXM	Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221 Descriptor: ATP-citrate synthase, CITRATE ANION, COENZYME A Authors: Verstraete, K, Verschueren, K. Deposit date: 2018-10-17 Release date: 2019-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
6HXL	Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH (space group P21) Descriptor: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ... Authors: Verstraete, K, Verschueren, K. Deposit date: 2018-10-17 Release date: 2019-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
8GQZ	Crystal structure of mitochondrial citrate synthase (Cit1) from Saccharomyces cerevisiae Descriptor: ACETATE ION, CHLORIDE ION, Citrate synthase, ... Authors: Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. Deposit date: 2022-08-31 Release date: 2023-04-26 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
6HXP	Structure of citryl-CoA lyase from Hydrogenobacter thermophilus Descriptor: COENZYME A, Citryl-CoA lyase, SULFATE ION Authors: Verstraete, K, Verschueren, K. Deposit date: 2018-10-17 Release date: 2019-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
8GR9	Crystal structure of peroxisomal citrate synthase (Cit2) from Saccharomyces cerevisiae in complex with oxaloacetate and coenzyme-A Descriptor: CHLORIDE ION, COENZYME A, Citrate synthase, ... Authors: Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. Deposit date: 2022-09-01 Release date: 2023-04-26 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
6HXO	Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P21) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ATP-citrate lyase alpha-subunit, CITRATE ANION Authors: Verstraete, K, Verschueren, K. Deposit date: 2018-10-17 Release date: 2019-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
1IOM	CRYSTAL STRUCTURE OF CITRATE SYNTHASE FROM THERMUS THERMOPHILUS HB8 Descriptor: CARBONATE ION, CITRATE SYNTHASE, GLYCEROL, ... Authors: Kanamori, E, Kouyama, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2001-03-19 Release date: 2003-07-29 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural comparison between the open and closed forms of citrate synthase from Thermus thermophilus HB8. Biophys Physicobio., 12, 2015
6S6F	Crystal structure of 2-methylcitrate synthase (PrpC) from Pseudomonas aeruginosa in apo form. Descriptor: CHLORIDE ION, Citrate synthase, GLYCEROL Authors: Wijaya, A.J, Brear, P, Dolan, S.K, Welch, M. Deposit date: 2019-07-03 Release date: 2020-10-14 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Crystal structure of 2-methylcitrate synthase (PrpC) from Pseudomonas aeruginosa in apo form. To Be Published
6QCL	Citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase in complex with acetyl-CoA and L-malate Descriptor: (2S)-2-hydroxybutanedioic acid, ACETYL COENZYME *A, ATP-citrate lyase alpha-subunit, ... Authors: Verstraete, K, Verschueren, K. Deposit date: 2018-12-28 Release date: 2019-04-10 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
5UQS	Crystal structure of Citrate synthase from Sus scrofa Descriptor: CHLORIDE ION, Citrate synthase, mitochondrial Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-08 Release date: 2018-02-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
2IBP	Crystal Structure of Citrate Synthase from Pyrobaculum aerophilum Descriptor: ACETATE ION, Citrate synthase, MAGNESIUM ION Authors: Boutz, D.R, Yeates, T.O, Cascio, D. Deposit date: 2006-09-11 Release date: 2007-05-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Discovery of a thermophilic protein complex stabilized by topologically interlinked chains. J.Mol.Biol., 368, 2007
1CSH	A very short hydrogen bond provides only moderate stabilization of an enzyme: inhibitor complex of citrate synthase Descriptor: AMIDOCARBOXYMETHYLDETHIA COENZYME *A, CITRATE SYNTHASE, OXALOACETATE ION Authors: Usher, K.C, Remington, S.J. Deposit date: 1994-03-07 Release date: 1994-04-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.65 Å) Cite: A very short hydrogen bond provides only moderate stabilization of an enzyme-inhibitor complex of citrate synthase. Biochemistry, 33, 1994
6S87	Crystal structure of 2-methylcitrate synthase (PrpC) from Pseudomonas aeruginosa in complex with oxaloacetate. Descriptor: Citrate synthase, GLYCEROL, OXALOACETATE ION Authors: Wijaya, A.J, Brear, P, Dolan, S.K, Welch, M. Deposit date: 2019-07-08 Release date: 2020-10-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of 2-methylcitrate synthase (PrpC) from Pseudomonas aeruginosa in complex with oxaloacetate. To Be Published
1CSC	Structure of ternary complexes of citrate synthase with D-and L-malate: Mechanistic implications Descriptor: (2S)-2-hydroxybutanedioic acid, CARBOXYMETHYL COENZYME *A, CITRATE SYNTHASE Authors: Karpusas, M, Holland, D, Remington, S.J. Deposit date: 1990-05-07 Release date: 1991-04-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications. Biochemistry, 30, 1991
1CSS	ALPHA-FLUORO ACID AND ALPHA-FLUORO AMIDE ANALOGS OF ACETYL-COA AS INHIBITORS OF OF CITRATE SYNTHASE: EFFECT OF PKA MATCHING ON BINDING AFFINITY AND HYDROGEN BOND LENGTH Descriptor: ALPHA-FLUORO-CARBOXYMETHYLDETHIA COENZYME A COMPLEX, CITRATE SYNTHASE, OXALOACETATE ION Authors: Usher, K.C, Remington, S.J. Deposit date: 1995-08-04 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: alpha-Fluoro acid and alpha-fluoro amide analogs of acetyl-CoA as inhibitors of citrate synthase: effect of pKa matching on binding affinity and hydrogen bond length. Biochemistry, 34, 1995
1CSI	A very short hydrogen bond provides only moderate stabilization of an enzyme: inhibitor complex of citrate synthase Descriptor: CARBOXYMETHYLDETHIA COENZYME *A, CITRATE SYNTHASE, OXALOACETATE ION Authors: Usher, K.C, Remington, S.J. Deposit date: 1994-03-07 Release date: 1994-04-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A very short hydrogen bond provides only moderate stabilization of an enzyme-inhibitor complex of citrate synthase. Biochemistry, 33, 1994
2IFC	The Structure of the Binary Complex of Oxalateacetate with Citrate Synthase from the Thermophilic Archaeon Thermolasma acidophilum Descriptor: Citrate Synthase, OXALOACETATE ION Authors: Lehmann, C. Deposit date: 2006-09-20 Release date: 2007-10-02 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.7 Å) Cite: To be anounced To be Published
1CSR	Alpha-fluoro acid and alpha-fluoro amide analogs of acetyl-coa as inhibitors of of citrate synthase: effect of pka matching on binding affinity and hydrogen bond length Descriptor: ALPHA-FLUORO-AMIDOCARBOXYMETHYLDETHIA COENZYME A COMPLEX, CITRATE SYNTHASE, OXALOACETATE ION Authors: Usher, K.C, Remington, S.J. Deposit date: 1995-08-04 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: alpha-Fluoro acid and alpha-fluoro amide analogs of acetyl-CoA as inhibitors of citrate synthase: effect of pKa matching on binding affinity and hydrogen bond length. Biochemistry, 34, 1995
6ABX	Crystal structure of citrate synthase (Msed_1522) from Metallosphaera sedula in complex with citrate Descriptor: CITRATE ANION, Citrate synthase, GLYCEROL Authors: Lee, S.-H, Son, H.-F, Kim, K.-J. Deposit date: 2018-07-24 Release date: 2019-03-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural insights into the inhibition properties of archaeon citrate synthase from Metallosphaera sedula. PLoS ONE, 14, 2019
6HXN	Structure of the citryl-CoA lyase core module of Chlorobium limicola ATP citrate lyase (space group P3121) Descriptor: ATP-citrate lyase alpha-subunit, COENZYME A, SULFATE ION Authors: Verstraete, K, Verschueren, K. Deposit date: 2018-10-17 Release date: 2019-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
5UQU	Crystal structure of mutant 2-methylcitrate synthase (mcsAG352A) from Aspergillus fumigatus Descriptor: 2-methylcitrate synthase, mitochondrial, COENZYME A, ... Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-08 Release date: 2018-02-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
2CSC	Structure of ternary complexes of CITRATE SYNTHASE WITH D-AND L-MALATE: mechanistic implications Descriptor: CARBOXYMETHYL COENZYME *A, CITRATE SYNTHASE, D-MALATE Authors: Karpusas, M, Holland, D, Remington, S.J. Deposit date: 1990-05-07 Release date: 1991-04-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: 1.9-A structures of ternary complexes of citrate synthase with D- and L-malate: mechanistic implications. Biochemistry, 30, 1991
6ABW	Crystal structure of citrate synthase (Msed_0281) from Metallosphaera sedula in complex with acetyl-CoA Descriptor: ACETYL COENZYME *A, Citrate synthase, GLYCEROL Authors: Lee, S.-H, Kim, K.-J. Deposit date: 2018-07-24 Release date: 2019-01-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Crystal structure and biochemical properties of msed_0281, the citrate synthase from Metallosphaera sedula. Biochem. Biophys. Res. Commun., 509, 2019
5UQR	Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus Descriptor: 2-methylcitrate synthase, mitochondrial, OXALOACETATE ION, ... Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-08 Release date: 2018-03-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
3ENJ	Structure of Pig Heart Citrate Synthase at 1.78 A resolution Descriptor: CHLORIDE ION, CYSTEINE, Citrate synthase, ... Authors: Larson, S.B, Day, J.S, Nguyen, C, Cudney, R, McPherson, A, Center for High-Throughput Structural Biology (CHTSB) Deposit date: 2008-09-25 Release date: 2009-02-03 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structure of pig heart citrate synthase at 1.78 A resolution. Acta Crystallogr.,Sect.F, 65, 2009

 

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