2A65
  • Download 2a65
  • View 2a65
Molmil generated image of 2a65
CRYSTAL STRUCTURE OF LEUTAA, A BACTERIAL HOMOLOG OF NA+/CL--DEPENDENT NEUROTRANSMITTER TRANSPORTERS
Descriptor:Na(+):neurotransmitter symporter (Snf family), B-OCTYLGLUCOSIDE, SODIUM ION, ...
Authors:Yamashita, A., Singh, S.K., Kawate, T., Jin, Y., Gouaux, E.
Deposit date:2005-07-01
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of a bacterial homologue of Na(+)/Cl(-)-dependent neurotransmitter transporters.
Nature, 437, 2005
4HQJ
  • Download 4hqj
  • View 4hqj
Molmil generated image of 4hqj
CRYSTAL STRUCTURE OF NA+,K+-ATPASE IN THE NA+-BOUND STATE
Descriptor:Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Nyblom, M., Reinhard, L., Gourdon, P., Nissen, P.
Deposit date:2012-10-25
Release date:2013-10-02
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Crystal structure of Na+, K(+)-ATPase in the Na(+)-bound state.
Science, 342, 2013
4PV2
  • Download 4pv2
  • View 4pv2
Molmil generated image of 4pv2
CRYSTAL STRUCTURE OF POTASSIUM-DEPENDENT PLANT-TYPE L-ASPARAGINASE FROM PHASEOLUS VULGARIS IN COMPLEX WITH K+ AND NA+ CATIONS
Descriptor:L-ASPARAGINASE ALPHA SUBUNIT, L-ASPARAGINASE BETA SUBUNIT, SODIUM ION, ...
Authors:Bejger, M., Gilski, M., Imiolczyk, B., Clavel, D., Jaskolski, M.
Deposit date:2014-03-14
Release date:2014-09-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Na+/K+ exchange switches the catalytic apparatus of potassium-dependent plant L-asparaginase
Acta Crystallogr.,Sect.D, 70, 2014
4PV3
  • Download 4pv3
  • View 4pv3
Molmil generated image of 4pv3
CRYSTAL STRUCTURE OF POTASSIUM-DEPENDENT PLANT-TYPE L-ASPARAGINASE FROM PHASEOLUS VULGARIS IN COMPLEX WITH NA+ CATIONS
Descriptor:L-ASPARAGINASE ALPHA SUBUNIT, L-ASPARAGINASE BETA SUBUNIT, SODIUM ION
Authors:Bejger, M., Gilski, M., Imiolczyk, B., Jaskolski, M.
Deposit date:2014-03-14
Release date:2014-09-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Na+/K+ exchange switches the catalytic apparatus of potassium-dependent plant L-asparaginase
Acta Crystallogr.,Sect.D, 70, 2014
4P6V
  • Download 4p6v
  • View 4p6v
Molmil generated image of 4p6v
CRYSTAL STRUCTURE OF THE NA+-TRANSLOCATING NADH: UBIQUINONE OXIDOREDUCTASE FROM VIBRIO CHOLERAE
Descriptor:Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-translocating NADH-quinone reductase subunit C, ...
Authors:Steuber, J., Casutt, M.S., Vohl, G., Vorburger, T., Diederichs, K., Fritz, G.
Deposit date:2014-03-25
Release date:2014-12-03
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase.
Nature, 516, 2014
1Q3I
  • Download 1q3i
  • View 1q3i
Molmil generated image of 1q3i
CRYSTAL STRUCTURE OF NA,K-ATPASE N-DOMAIN
Descriptor:Na,K-ATPase, NICKEL (II) ION
Authors:Hakansson, K.O.
Deposit date:2003-07-30
Release date:2004-08-03
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystallographic Structure of Na,K-ATPase N-domain at 2.6 A Resolution
J.Mol.Biol., 332, 2003
4HYT
  • Download 4hyt
  • View 4hyt
Molmil generated image of 4hyt
NA,K-ATPASE IN THE E2P STATE WITH BOUND OUABAIN AND MG2+ IN THE CATION-BINDING SITE
Descriptor:Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Laursen, M., Yatime, L., Nissen, P., Fedosova, N.U.
Deposit date:2012-11-14
Release date:2013-06-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.404 Å)
Cite:Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site.
Proc.Natl.Acad.Sci.USA, 110, 2013
4U9U
  • Download 4u9u
  • View 4u9u
Molmil generated image of 4u9u
CRYSTAL STRUCTURE OF NQRF FAD-BINDING DOMAIN FROM VIBRIO CHOLERAE
Descriptor:Na(+)-translocating NADH-quinone reductase subunit F, FLAVIN-ADENINE DINUCLEOTIDE, ACETATE ION, ...
Authors:Fritz, G.
Deposit date:2014-08-06
Release date:2014-12-03
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase.
Nature, 516, 2014
1ZCD
  • Download 1zcd
  • View 1zcd
Molmil generated image of 1zcd
CRYSTAL STRUCTURE OF THE NA+/H+ ANTIPORTER NHAA
Descriptor:Na(+)/H(+) antiporter 1
Authors:Hunte, C., Screpanti, E., Venturi, M., Rimon, A., Padan, E., Michel, H.
Deposit date:2005-04-11
Release date:2005-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH.
Nature, 435, 2005
2AHY
  • Download 2ahy
  • View 2ahy
Molmil generated image of 2ahy
NA+ COMPLEX OF THE NAK CHANNEL
Descriptor:Potassium channel protein, SODIUM ION, CALCIUM ION
Authors:Shi, N., Ye, S., Alam, A., Chen, L., Jiang, Y.
Deposit date:2005-07-28
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structure of a Na+- and K+-conducting channel.
Nature, 440, 2006
3BEU
  • Download 3beu
  • View 3beu
Molmil generated image of 3beu
NA+-DEPENDENT ALLOSTERY MEDIATES COAGULATION FACTOR PROTEASE ACTIVE SITE SELECTIVITY
Descriptor:Trypsin, SULFATE ION, BENZAMIDINE, ...
Authors:Page, M.J., Carrell, C.J., Di Cera, E.
Deposit date:2007-11-20
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Engineering protein allostery: 1.05 A resolution structure and enzymatic properties of a Na+-activated trypsin.
J.Mol.Biol., 378, 2008
5JOC
  • Download 5joc
  • View 5joc
Molmil generated image of 5joc
CRYSTAL STRUCTURE OF THE S61A MUTANT OF AMPC BER
Descriptor:Beta-lactamase, CITRIC ACID
Authors:Na, J.H., An, Y.J., Cha, S.S.
Deposit date:2016-05-02
Release date:2017-05-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for the extended substrate spectrum of AmpC BER and structure-guided discovery of the inhibition activity of citrate against the class C beta-lactamases AmpC BER and CMY-10.
Acta Crystallogr D Struct Biol, 72, 2016
5JXE
  • Download 5jxe
  • View 5jxe
Molmil generated image of 5jxe
HUMAN PD-1 ECTODOMAIN COMPLEXED WITH PEMBROLIZUMAB FAB
Descriptor:Programmed cell death protein 1, Pembrolizumab Fab light chain, Pembrolizumab Fab heavy chain
Authors:Na, Z., Bharath, S.R., Song, H.
Deposit date:2016-05-13
Release date:2016-08-10
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab.
Cell Res., 27, 2017
5WU7
  • Download 5wu7
  • View 5wu7
Molmil generated image of 5wu7
CRYSTAL STRUCTURE OF GH57-TYPE BRANCHING ENZYME FROM HYPERTHERMOPHILIC ARCHAEON PYROCOCCUS HORIKOSHII
Descriptor:Uncharacterized protein, GLYCEROL
Authors:Na, S., Jo, I., Ha, N.-C.
Deposit date:2016-12-16
Release date:2017-03-08
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural basis for the transglycosylase activity of a GH57-type glycogen branching enzyme from Pyrococcus horikoshii.
Biochem. Biophys. Res. Commun., 484, 2017
6KNS
  • Download 6kns
  • View 6kns
Molmil generated image of 6kns
CRYSTAL STRUCTURE OF THE METALLO-BETA-LACTAMASE FOLD PROTEIN YHFI FROM BACILLUS SUBTILIS (SPACE GROUP I4122)
Descriptor:Putative metal-dependent hydrolase, CALCIUM ION, ZINC ION
Authors:Na, H.W., Namgung, B., Song, W.S., Yoon, S.I.
Deposit date:2019-08-07
Release date:2019-09-18
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and biochemical analyses of the metallo-beta-lactamase fold protein YhfI from Bacillus subtilis.
Biochem.Biophys.Res.Commun., 519, 2019
6KNT
  • Download 6knt
  • View 6knt
Molmil generated image of 6knt
CRYSTAL STRUCTURE OF THE METALLO-BETA-LACTAMASE FOLD PROTEIN YHFI FROM BACILLUS SUBTILIS (SPACE GROUP P4332)
Descriptor:Putative metal-dependent hydrolase, ZINC ION
Authors:Na, H.W., Namgung, B., Song, W.S., Yoon, S.I.
Deposit date:2019-08-07
Release date:2019-09-18
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and biochemical analyses of the metallo-beta-lactamase fold protein YhfI from Bacillus subtilis.
Biochem.Biophys.Res.Commun., 519, 2019
4RES
  • Download 4res
  • View 4res
Molmil generated image of 4res
CRYSTAL STRUCTURE OF THE NA,K-ATPASE E2P-BUFALIN COMPLEX WITH BOUND POTASSIUM
Descriptor:Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Laursen, M., Yatime, L., Gregersen, J.L., Nissen, P., Fedosova, N.U.
Deposit date:2014-09-23
Release date:2015-01-28
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (3.408 Å)
Cite:Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
4RET
  • Download 4ret
  • View 4ret
Molmil generated image of 4ret
CRYSTAL STRUCTURE OF THE NA,K-ATPASE E2P-DIGOXIN COMPLEX WITH BOUND MAGNESIUM
Descriptor:Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Gregersen, J.L., Laursen, M., Yatime, L., Nissen, P., Fedosova, N.U.
Deposit date:2014-09-23
Release date:2015-01-28
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
5NV9
  • Download 5nv9
  • View 5nv9
Molmil generated image of 5nv9
SUBSTRATE-BOUND OUTWARD-OPEN STATE OF A NA+-COUPLED SIALIC ACID SYMPORTER REVEALS A NOVEL NA+-SITE
Descriptor:Putative sodium:solute symporter, SODIUM ION, 5-N-ACETYL-BETA-D-NEURAMINIC ACID, ...
Authors:Wahlgren, W.Y., North, R.A., Dunevall, E., Paz, A., Goyal, P., Bisignano, P., Grabe, M., Dobson, R., Abramson, J., Ramaswamy, S., Friemann, R.
Deposit date:2017-05-03
Release date:2018-04-04
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+site.
Nat Commun, 9, 2018
5NVA
  • Download 5nva
  • View 5nva
Molmil generated image of 5nva
SUBSTRATE-BOUND OUTWARD-OPEN STATE OF A NA+-COUPLED SIALIC ACID SYMPORTER REVEALS A NOVEL NA+-SITE
Descriptor:Putative sodium:solute symporter, SODIUM ION, 5-N-ACETYL-BETA-D-NEURAMINIC ACID
Authors:Wahlgren, W.Y., North, R.A., Dunevall, E., Goyal, P., Grabe, M., Dobson, R., Abramson, J., Ramaswamy, S., Friemann, R.
Deposit date:2017-05-03
Release date:2018-04-04
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+site.
Nat Commun, 9, 2018
3JZ1
  • Download 3jz1
  • View 3jz1
Molmil generated image of 3jz1
CRYSTAL STRUCTURE OF HUMAN THROMBIN MUTANT N143P IN E:NA+ FORM
Descriptor:Thrombin light chain, Thrombin heavy chain, SODIUM ION, ...
Authors:Niu, W., Chen, Z., Bush-Pelc, L.A., Bah, A., Gandhi, P.S., Di Cera, E.
Deposit date:2009-09-22
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mutant N143P reveals how Na+ activates thrombin
J.Biol.Chem., 284, 2009
6QK8
  • Download 6qk8
  • View 6qk8
Molmil generated image of 6qk8
CRYSTAL STRUCTURE OF YEAST 14-3-3 PROTEIN (BMH1) FROM SACCHAROMYCES CEREVISIAE WITH THE NHA1P (YEAST NA+/H+ ANTIPORTER) 14-3-3 BINDING MOTIF SER481
Descriptor:Protein BMH1, Na(+)/H(+) antiporter
Authors:Smidova, A., Obsil, T., Obsilova, V.
Deposit date:2019-01-28
Release date:2019-10-02
Method:X-RAY DIFFRACTION (2.917 Å)
Cite:The activity of Saccharomyces cerevisiae Na+, K+/H+antiporter Nha1 is negatively regulated by 14-3-3 protein binding at serine 481.
Biochim Biophys Acta Mol Cell Res, 1866, 2019
1BG5
  • Download 1bg5
  • View 1bg5
Molmil generated image of 1bg5
CRYSTAL STRUCTURE OF THE ANKYRIN BINDING DOMAIN OF ALPHA-NA,K-ATPASE AS A FUSION PROTEIN WITH GLUTATHIONE S-TRANSFERASE
Descriptor:FUSION PROTEIN OF ALPHA-NA,K-ATPASE WITH GLUTATHIONE S-TRANSFERASE
Authors:Zhang, Z., Devarajan, P., Morrow, J.S.
Deposit date:1998-06-05
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the ankyrin-binding domain of alpha-Na,K-ATPase.
J.Biol.Chem., 273, 1998
1YCE
  • Download 1yce
  • View 1yce
Molmil generated image of 1yce
STRUCTURE OF THE ROTOR RING OF F-TYPE NA+-ATPASE FROM ILYOBACTER TARTARICUS
Descriptor:subunit c, SODIUM ION, NONAN-1-OL
Authors:Meier, T., Polzer, P., Diederichs, K., Welte, W., Dimroth, P.
Deposit date:2004-12-22
Release date:2005-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the rotor ring of F-Type Na+-ATPase from Ilyobacter tartaricus.
Science, 308, 2005
2A2Q
  • Download 2a2q
  • View 2a2q
Molmil generated image of 2a2q
COMPLEX OF ACTIVE-SITE INHIBITED HUMAN COAGULATION FACTOR VIIA WITH HUMAN SOLUBLE TISSUE FACTOR IN THE PRESENCE OF CA2+, MG2+, NA+, AND ZN2+
Descriptor:Coagulation factor VII, Tissue factor, ALPHA-D-GLUCOSE, ...
Authors:Bajaj, S.P., Bajaj, M., Schmidt, A.E., Padmanabhan, K.
Deposit date:2005-06-22
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa.
J.Biol.Chem., 281, 2006