9G2R
| |
9G2G
| Staphylococcus aureus MazF in complex with nanobody 5 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoribonuclease MazF, Nanobody 5 | Authors: | Prolic-Kalinsek, M, Zorzini, V, Haesaerts, S, Loris, R. | Deposit date: | 2024-07-10 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.80048239 Å) | Cite: | Nanobody-mediated activation and inhibition of Staphylococcus aureus MazF To Be Published
|
|
9G2A
| Staphylococcus aureus MazF in complex with nanobody 4 | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endoribonuclease MazF, ... | Authors: | Prolic-Kalinsek, M, Zorzini, V, Haesaerts, S, Loris, R. | Deposit date: | 2024-07-10 | Release date: | 2024-07-17 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.046594 Å) | Cite: | Staphylococcus aureus MazF in complex with nanobody 4. To Be Published
|
|
9G1Y
| |
9G13
| VHH H3-2 in complex with Tau C-terminal peptide | Descriptor: | Isoform Tau-F of Microtubule-associated protein tau, VHH H3-2 | Authors: | Dupre, E, Landrieu, I, Danis, C, Hanoulle, X, Mortelecque, J. | Deposit date: | 2024-07-09 | Release date: | 2024-07-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | VHH H3-2 in complex with Tau C-terminal peptide To Be Published
|
|
9G11
| |
9G0K
| CysG(N-16) in complex with SAH (metal free, cocrystallization in presence of EDTA) from Kitasatospora cystarginea | Descriptor: | 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, SAM-dependent methyltransferase | Authors: | Kuttenlochner, W, Beller, P, Kaysser, L, Groll, M. | Deposit date: | 2024-07-08 | Release date: | 2024-07-17 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Deciphering the SAM- and metal-dependent mechanism of O-methyltransferases in cystargolide and belactosin biosynthesis: A structure-activity relationship study. J.Biol.Chem., 300, 2024
|
|
9G0B
| |
9FZK
| |
9FZD
| |
9FZC
| |
9FZ4
| |
9FYP
| Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH. | Descriptor: | Alpha-synuclein, CHLORIDE ION | Authors: | Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. | Deposit date: | 2024-07-03 | Release date: | 2024-07-17 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation. Elife, 12, 2024
|
|
9FYF
| Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with TR06772818 | Descriptor: | Casein kinase II subunit alpha, SULFATE ION, ~{N}-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-4-fluoranyl-2-[(3~{S})-3-(methylamino)piperidin-1-yl]phenyl]propanamide | Authors: | Kraemer, A, Ong, H.W, Yang, X, Brown, J.W, Chang, E, Willson, T, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2024-07-03 | Release date: | 2024-09-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with TR06772818 To Be Published
|
|
9FYB
| Structural Insights into the NMN Complex of Nicotinate Nucleotide Adenylyltransferase from Enterococcus faecium via Co-Crystallization Studies | Descriptor: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Pandian, R, Jeje, O.A, Sayed, Y, Achilonu, I.A. | Deposit date: | 2024-07-03 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structural Insights into the NMN Complex of Nicotinate Nucleotide Adenylyltransferase from Enterococcus faecium via Co-Crystallization Studies To be published
|
|
9FXP
| Crystal structure of BRD4 BD1 with DI00626383. | Descriptor: | 4-methoxy-1,2-benzoxazol-3-amine, Bromodomain-containing protein 4 | Authors: | Bader, G, Reinert, D. | Deposit date: | 2024-07-02 | Release date: | 2024-08-07 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Probing Protein-Ligand Methyl-pi Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups. J.Med.Chem., 67, 2024
|
|
9FXN
| |
9FXJ
| Crystal structure of cobalt(II)-substituted double mutant Y115E Y117E human Glutaminyl Cyclase in complex with PBD-150 | Descriptor: | 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, COBALT (II) ION, Glutaminyl-peptide cyclotransferase, ... | Authors: | Tassone, G, Pozzi, C, Mangani, S. | Deposit date: | 2024-07-01 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. Int J Mol Sci, 25, 2024
|
|
9FXI
| Crystal structure of cobalt(II)-substituted double mutant Y115E Y117E human Glutaminyl Cyclase in complex with SEN177 | Descriptor: | 2-fluoranyl-5-[2-[4-(4-methyl-1,2,4-triazol-3-yl)piperidin-1-yl]pyridin-3-yl]pyridine, COBALT (II) ION, Glutaminyl-peptide cyclotransferase, ... | Authors: | Tassone, G, Pozzi, C, Mangani, S. | Deposit date: | 2024-07-01 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. Int J Mol Sci, 25, 2024
|
|
9FXH
| Crystal structure of cobalt(II)-substituted double mutant Y115E Y117E human Glutaminyl Cyclase | Descriptor: | COBALT (II) ION, GLYCEROL, Glutaminyl-peptide cyclotransferase, ... | Authors: | Tassone, G, Pozzi, C, Mangani, S. | Deposit date: | 2024-07-01 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. Int J Mol Sci, 25, 2024
|
|
9FXG
| Crystal structure of double mutant Y115E Y117E human Glutaminyl Cyclase in apo-state | Descriptor: | 1,2-ETHANEDIOL, Glutaminyl-peptide cyclotransferase, SULFATE ION | Authors: | Tassone, G, Pozzi, C, Mangani, S. | Deposit date: | 2024-07-01 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective. Int J Mol Sci, 25, 2024
|
|
9FX7
| Crystal structure of Cryo2RT SARS-CoV-2 main protease at 294K | Descriptor: | 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | Authors: | Huang, C.Y, Aumonier, S, Mac Sweeney, A, Olieric, V, Wang, M. | Deposit date: | 2024-07-01 | Release date: | 2024-07-31 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.282 Å) | Cite: | Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryo-cooled crystals. Acta Crystallogr D Struct Biol, 80, 2024
|
|
9FX6
| Crystal structure of Cryo2RT SARS-CoV-2 main protease at 100K | Descriptor: | 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | Authors: | Huang, C.Y, Aumonier, S, Mac Sweeney, A, Olieric, V, Wang, M. | Deposit date: | 2024-07-01 | Release date: | 2024-07-31 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.227 Å) | Cite: | Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryo-cooled crystals. Acta Crystallogr D Struct Biol, 80, 2024
|
|
9FX5
| Crystal structure of Cryo2RT Thaumatin at 296K | Descriptor: | L(+)-TARTARIC ACID, Thaumatin I | Authors: | Huang, C.Y, Aumonier, S, Olieric, V, Wang, M. | Deposit date: | 2024-07-01 | Release date: | 2024-07-31 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (1.592 Å) | Cite: | Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryo-cooled crystals. Acta Crystallogr D Struct Biol, 80, 2024
|
|
9FX4
| Crystal structure of Cryo2RT Thaumatin at 100K | Descriptor: | L(+)-TARTARIC ACID, Thaumatin I | Authors: | Huang, C.Y, Aumonier, S, Olieric, V, Wang, M. | Deposit date: | 2024-07-01 | Release date: | 2024-07-31 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryo-cooled crystals. Acta Crystallogr D Struct Biol, 80, 2024
|
|