9G0K

CysG(N-16) in complex with SAH (metal free, cocrystallization in presence of EDTA) from Kitasatospora cystarginea

Summary for 9G0K

Entry DOI	10.2210/pdb9g0k/pdb
Related	9FCD
Descriptor	SAM-dependent methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	natural product biosynthesis, enzyme mechanism, metal ion interaction, molecular docking, structure function relationships, transferase
Biological source	Kitasatospora cystarginea
Total number of polymer chains	2
Total formula weight	48750.80
Authors	Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M. (deposition date: 2024-07-08, release date: 2024-07-17, Last modification date: 2024-09-18)
Primary citation	Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M. Deciphering the SAM- and metal-dependent mechanism of O-methyltransferases in cystargolide and belactosin biosynthesis: A structure-activity relationship study. J.Biol.Chem., 300:107646-107646, 2024 Cited by PubMed: 39121999 DOI: 10.1016/j.jbc.2024.107646 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation