9FXP

Crystal structure of BRD4 BD1 with DI00626383.

Summary for 9FXP

Entry DOI	10.2210/pdb9fxp/pdb
Descriptor	Bromodomain-containing protein 4, 4-methoxy-1,2-benzoxazol-3-amine (3 entities in total)
Functional Keywords	inhibitor, bromodomain, protein binding
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	15263.54
Authors	Bader, G.,Reinert, D. (deposition date: 2024-07-02, release date: 2024-08-07, Last modification date: 2024-08-21)
Primary citation	Beier, A.,Platzer, G.,Hofurthner, T.,Ptaszek, A.L.,Lichtenecker, R.J.,Geist, L.,Fuchs, J.E.,McConnell, D.B.,Mayer, M.,Konrat, R. Probing Protein-Ligand Methyl-pi Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups. J.Med.Chem., 67:13187-13196, 2024 Cited by PubMed: 39069741 DOI: 10.1021/acs.jmedchem.4c01128 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation