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7PVW	Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H mutant Descriptor: ACETATE ION, Isoform 1 of Proto-oncogene tyrosine-protein kinase Src, TETRAETHYLENE GLYCOL Authors: Camara-Artigas, A, Salinas Garcia, M.C. Deposit date: 2021-10-05 Release date: 2022-09-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PW0	Crystal structure of the c-Src SH3 domain N112G-N113Y-T114N-E115H mutant Descriptor: Isoform 1 of Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Salinas Garcia, M.C. Deposit date: 2021-10-05 Release date: 2022-09-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PVY	Crystal structure of the c-Src SH3 domain E93V-S94A-R95S-T96G mutant Descriptor: Isoform 2 of Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Salinas Garcia, M.C. Deposit date: 2021-10-05 Release date: 2022-09-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PVZ	Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G mutant Descriptor: Isoform 2 of Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Salinas Garcia, M.C. Deposit date: 2021-10-05 Release date: 2022-11-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
5NP3	Abl2 SH3 Descriptor: Abelson tyrosine-protein kinase 2 Authors: Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. Deposit date: 2017-04-13 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
5O2P	p130Cas SH3 domain PTP-PEST peptide chimera Descriptor: Breast cancer anti-estrogen resistance 1,Tyrosine-protein phosphatase non-receptor type 12 Authors: Hexnerova, R, Veverka, V. Deposit date: 2017-05-22 Release date: 2017-09-20 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep, 7, 2017
5OAZ	Crystal structure of the Abl-SH3 domain at pH 7.5 Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2017-06-25 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.03 Å) Cite: Crystal structure of the Abl-SH3 domain at pH 7.5 to be published
5OB0	Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12 Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION Authors: Camara-Artigas, A. Deposit date: 2017-06-25 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.172 Å) Cite: Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12 to be published
5OB2	Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12 Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2017-06-25 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12 to be published
5OAV	High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2017-06-23 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (0.95 Å) Cite: High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal to be published
5OB1	Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12 Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2017-06-25 Release date: 2017-07-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.172 Å) Cite: Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12 to be published
5O2Q	p130Cas SH3 domain Vinculin peptide chimera Descriptor: Breast cancer anti-estrogen resistance 1,Vinculin Authors: Hexnerova, R, Veverka, V. Deposit date: 2017-05-22 Release date: 2017-09-20 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep, 7, 2017
5O2M	p130Cas SH3 domain Descriptor: Breast cancer anti-estrogen resistance 1 Authors: Hexnerova, R, Veverka, V. Deposit date: 2017-05-22 Release date: 2017-09-20 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep, 7, 2017
5NP5	Abl2 SH3 pTyr116/161 Descriptor: Abelson tyrosine-protein kinase 2, SULFATE ION Authors: Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. Deposit date: 2017-04-13 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
5NP2	Abl1 SH3 pTyr89/134 Descriptor: Tyrosine-protein kinase ABL1 Authors: Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. Deposit date: 2017-04-13 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
5FWB	Human Spectrin SH3 domain D48G, E7F, K60F Descriptor: SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1 Authors: Gallego, P, Navarro, S, Ventura, S, Reverter, D. Deposit date: 2016-02-12 Release date: 2016-12-28 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Human Spectrin SH3 Domain D48G, E7F, K60F To be Published
5HCK	HUMAN HCK SH3 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: HEMATOPOIETIC CELL KINASE Authors: Horita, D.A, Baldisseri, D.M, Zhang, W, Altieri, A.S, Smithgall, T.E, Gmeiner, W.H, Byrd, R.A. Deposit date: 1998-03-09 Release date: 1998-06-17 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of the human Hck SH3 domain and identification of its ligand binding site. J.Mol.Biol., 278, 1998
5IHK	Crystal Structure of the alpha spectrin SH3 domain mutant N47A Descriptor: ACETATE ION, PROLINE, SULFATE ION, ... Authors: Camara-Artigas, A. Deposit date: 2016-02-29 Release date: 2017-03-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain mutant N47A to be published
5IHN	Crystal Structure of the alpha spectrin SH3 domain mutant N47G Descriptor: FORMIC ACID, SODIUM ION, Spectrin alpha chain, ... Authors: Camara-Artigas, A. Deposit date: 2016-02-29 Release date: 2017-03-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain mutant N47G to be published
5I11	Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, ... Authors: Camara-Artigas, A. Deposit date: 2016-02-05 Release date: 2016-03-09 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant To Be Published
5IH2	Structure, thermodynamics, and the role of conformational dynamics in the interactions between the N-terminal SH3 domain of CrkII and proline-rich motifs in cAbl Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Adapter molecule crk, DI(HYDROXYETHYL)ETHER, ... Authors: Bhatt, V.S, Zeng, D, Krieger, I, Sacchettini, J.C, Cho, J.-H. Deposit date: 2016-02-28 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAbl. Biophys.J., 110, 2016
5IHI	Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, Spectrin alpha chain, ... Authors: Camara-Artigas, A. Deposit date: 2016-02-29 Release date: 2017-03-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G to be published
3THK	Structure of SH3 chimera with a type II ligand linked to the chain C-terminal Descriptor: BETA-MERCAPTOETHANOL, Proline-rich peptide, SULFATE ION, ... Authors: Gabdulkhakov, A.G, Gushchina, L.V, Nikulin, A.D, Nikonov, S.V, Filimonov, V.V. Deposit date: 2011-08-19 Release date: 2011-11-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: High-Resolution Crystal Structure of Spectrin SH3 Domain Fused with a Proline-Rich Peptide. J.Biomol.Struct.Dyn., 29, 2011
1ABO	CRYSTAL STRUCTURE OF THE COMPLEX OF THE ABL TYROSINE KINASE SH3 DOMAIN WITH 3BP-1 SYNTHETIC PEPTIDE Descriptor: 3BP-1 SYNTHETIC PEPTIDE, 10 RESIDUES, ABL TYROSINE KINASE, ... Authors: Musacchio, A, Wilmanns, M, Saraste, M. Deposit date: 1995-05-19 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
1ABQ	CRYSTAL STRUCTURE OF THE UNLIGANDED ABL TYROSINE KINASE SH3 DOMAIN Descriptor: ABL TYROSINE KINASE SRC-HOMOLOGY 3 (SH3) DOMAIN Authors: Musacchio, A, Wilmanns, M, Saraste, M. Deposit date: 1995-05-19 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.8 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994

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