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7PVW
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BU of 7pvw by Molmil
Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H mutant
Descriptor: ACETATE ION, Isoform 1 of Proto-oncogene tyrosine-protein kinase Src, TETRAETHYLENE GLYCOL
Authors:Camara-Artigas, A, Salinas Garcia, M.C.
Deposit date:2021-10-05
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The effect of the hinge loops composition in the domain swapping of the SH3 domain
To be published
7PW0
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BU of 7pw0 by Molmil
Crystal structure of the c-Src SH3 domain N112G-N113Y-T114N-E115H mutant
Descriptor: Isoform 1 of Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Salinas Garcia, M.C.
Deposit date:2021-10-05
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The effect of the hinge loops composition in the domain swapping of the SH3 domain
To be published
7PVY
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BU of 7pvy by Molmil
Crystal structure of the c-Src SH3 domain E93V-S94A-R95S-T96G mutant
Descriptor: Isoform 2 of Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Salinas Garcia, M.C.
Deposit date:2021-10-05
Release date:2022-09-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The effect of the hinge loops composition in the domain swapping of the SH3 domain
To be published
7PVZ
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BU of 7pvz by Molmil
Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G mutant
Descriptor: Isoform 2 of Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Salinas Garcia, M.C.
Deposit date:2021-10-05
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:The effect of the hinge loops composition in the domain swapping of the SH3 domain
To be published
5NP3
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BU of 5np3 by Molmil
Abl2 SH3
Descriptor: Abelson tyrosine-protein kinase 2
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5O2P
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BU of 5o2p by Molmil
p130Cas SH3 domain PTP-PEST peptide chimera
Descriptor: Breast cancer anti-estrogen resistance 1,Tyrosine-protein phosphatase non-receptor type 12
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5OAZ
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BU of 5oaz by Molmil
Crystal structure of the Abl-SH3 domain at pH 7.5
Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH 7.5
to be published
5OB0
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BU of 5ob0 by Molmil
Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.172 Å)
Cite:Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
to be published
5OB2
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BU of 5ob2 by Molmil
Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
to be published
5OAV
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BU of 5oav by Molmil
High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-23
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
to be published
5OB1
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BU of 5ob1 by Molmil
Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.172 Å)
Cite:Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
to be published
5O2Q
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BU of 5o2q by Molmil
p130Cas SH3 domain Vinculin peptide chimera
Descriptor: Breast cancer anti-estrogen resistance 1,Vinculin
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5O2M
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BU of 5o2m by Molmil
p130Cas SH3 domain
Descriptor: Breast cancer anti-estrogen resistance 1
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5NP5
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BU of 5np5 by Molmil
Abl2 SH3 pTyr116/161
Descriptor: Abelson tyrosine-protein kinase 2, SULFATE ION
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP2
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BU of 5np2 by Molmil
Abl1 SH3 pTyr89/134
Descriptor: Tyrosine-protein kinase ABL1
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5FWB
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BU of 5fwb by Molmil
Human Spectrin SH3 domain D48G, E7F, K60F
Descriptor: SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
Authors:Gallego, P, Navarro, S, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Human Spectrin SH3 Domain D48G, E7F, K60F
To be Published
5HCK
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BU of 5hck by Molmil
HUMAN HCK SH3 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: HEMATOPOIETIC CELL KINASE
Authors:Horita, D.A, Baldisseri, D.M, Zhang, W, Altieri, A.S, Smithgall, T.E, Gmeiner, W.H, Byrd, R.A.
Deposit date:1998-03-09
Release date:1998-06-17
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the human Hck SH3 domain and identification of its ligand binding site.
J.Mol.Biol., 278, 1998
5IHK
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BU of 5ihk by Molmil
Crystal Structure of the alpha spectrin SH3 domain mutant N47A
Descriptor: ACETATE ION, PROLINE, SULFATE ION, ...
Authors:Camara-Artigas, A.
Deposit date:2016-02-29
Release date:2017-03-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal Structure of the alpha spectrin SH3 domain mutant N47A
to be published
5IHN
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BU of 5ihn by Molmil
Crystal Structure of the alpha spectrin SH3 domain mutant N47G
Descriptor: FORMIC ACID, SODIUM ION, Spectrin alpha chain, ...
Authors:Camara-Artigas, A.
Deposit date:2016-02-29
Release date:2017-03-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of the alpha spectrin SH3 domain mutant N47G
to be published
5I11
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BU of 5i11 by Molmil
Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, ...
Authors:Camara-Artigas, A.
Deposit date:2016-02-05
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant
To Be Published
5IH2
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BU of 5ih2 by Molmil
Structure, thermodynamics, and the role of conformational dynamics in the interactions between the N-terminal SH3 domain of CrkII and proline-rich motifs in cAbl
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Adapter molecule crk, DI(HYDROXYETHYL)ETHER, ...
Authors:Bhatt, V.S, Zeng, D, Krieger, I, Sacchettini, J.C, Cho, J.-H.
Deposit date:2016-02-28
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAbl.
Biophys.J., 110, 2016
5IHI
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BU of 5ihi by Molmil
Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G
Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, Spectrin alpha chain, ...
Authors:Camara-Artigas, A.
Deposit date:2016-02-29
Release date:2017-03-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structure of the alpha spectrin SH3 domain double mutant V46G-D48G
to be published
3THK
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BU of 3thk by Molmil
Structure of SH3 chimera with a type II ligand linked to the chain C-terminal
Descriptor: BETA-MERCAPTOETHANOL, Proline-rich peptide, SULFATE ION, ...
Authors:Gabdulkhakov, A.G, Gushchina, L.V, Nikulin, A.D, Nikonov, S.V, Filimonov, V.V.
Deposit date:2011-08-19
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High-Resolution Crystal Structure of Spectrin SH3 Domain Fused with a Proline-Rich Peptide.
J.Biomol.Struct.Dyn., 29, 2011
1ABO
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BU of 1abo by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF THE ABL TYROSINE KINASE SH3 DOMAIN WITH 3BP-1 SYNTHETIC PEPTIDE
Descriptor: 3BP-1 SYNTHETIC PEPTIDE, 10 RESIDUES, ABL TYROSINE KINASE, ...
Authors:Musacchio, A, Wilmanns, M, Saraste, M.
Deposit date:1995-05-19
Release date:1995-10-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994
1ABQ
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BU of 1abq by Molmil
CRYSTAL STRUCTURE OF THE UNLIGANDED ABL TYROSINE KINASE SH3 DOMAIN
Descriptor: ABL TYROSINE KINASE SRC-HOMOLOGY 3 (SH3) DOMAIN
Authors:Musacchio, A, Wilmanns, M, Saraste, M.
Deposit date:1995-05-19
Release date:1995-10-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994

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