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6K71
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BU of 6k71 by Molmil
eIF2 - eIF2B complex
Descriptor: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ...
Authors:Kashiwagi, K, Yokoyama, T, Ito, T.
Deposit date:2019-06-05
Release date:2019-07-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019
5O9Z
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BU of 5o9z by Molmil
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ...
Authors:Bertram, K, Kastner, B.
Deposit date:2017-06-20
Release date:2017-08-16
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell, 170, 2017
5O8W
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BU of 5o8w by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor: Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ...
Authors:Wirth, C, Andersen, G.R, Hunte, C.
Deposit date:2017-06-14
Release date:2017-08-23
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
6U43
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BU of 6u43 by Molmil
Crystal structure of Methanoperedens nitroreducens elongation factor 2 H595N bound to GMPPCP and magnesium (triclinic crystal form)
Descriptor: CHLORIDE ION, Elongation factor 2, MAGNESIUM ION, ...
Authors:Fenwick, M.K, Ealick, S.E.
Deposit date:2019-08-22
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis of elongation factor 2 switching
Curr Res Struct Biol, 2, 2020
6SW9
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BU of 6sw9 by Molmil
IC2A model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Coureux, P.-D, Mechulam, Y, Schmitt, E.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation.
Commun Biol, 3, 2020
6UCQ
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BU of 6ucq by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome recycling complex
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Zhou, D, Tanzawa, T, Gagnon, M.G, Lin, J.
Deposit date:2019-09-17
Release date:2019-12-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for ribosome recycling by RRF and tRNA.
Nat.Struct.Mol.Biol., 27, 2020
1R5O
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BU of 1r5o by Molmil
crystal structure analysis of sup35 complexed with GMPPNP
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Kong, C, Song, H.
Deposit date:2003-10-11
Release date:2004-05-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
Mol.Cell, 14, 2004
5OPD
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BU of 5opd by Molmil
Structure of phosphorylated EF-Tu in complex with GTP
Descriptor: Elongation factor Tu 1, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Garcia-Pino, A.
Deposit date:2017-08-09
Release date:2018-08-29
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of phosphorylated EF-Tu in complex with GTP
To Be Published
6TEO
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BU of 6teo by Molmil
Crystal structure of a yeast Snu114-Prp8 complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ...
Authors:Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C.
Deposit date:2019-11-12
Release date:2020-03-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast.
Nucleic Acids Res., 48, 2020
1TTT
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BU of 1ttt by Molmil
Phe-tRNA, elongation factoR EF-TU:GDPNP ternary complex
Descriptor: MAGNESIUM ION, OF ELONGATION FACTOR TU (EF-TU), PHENYLALANINE, ...
Authors:Nissen, P, Kjeldgaard, M, Thirup, S, Polekhina, G, Reshetnikova, L, Clark, B.F.C, Nyborg, J.
Deposit date:1995-11-16
Release date:1996-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog.
Science, 270, 1995
5NRL
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BU of 5nrl by Molmil
Structure of a pre-catalytic spliceosome.
Descriptor: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ...
Authors:Plaschka, C, Lin, P.-C, Nagai, K.
Deposit date:2017-04-24
Release date:2017-05-31
Last modified:2023-05-24
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structure of a pre-catalytic spliceosome.
Nature, 546, 2017
1TUI
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BU of 1tui by Molmil
INTACT ELONGATION FACTOR TU IN COMPLEX WITH GDP
Descriptor: ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Polekhina, G, Thirup, S, Kjeldgaard, M, Nissen, P, Lippmann, C, Nyborg, J.
Deposit date:1996-05-23
Release date:1997-06-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Helix unwinding in the effector region of elongation factor EF-Tu-GDP.
Structure, 4, 1996
5MI9
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BU of 5mi9 by Molmil
Structure of the phosphomimetic mutant of the elongation factor EF-Tu T62E
Descriptor: Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
6SWC
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BU of 6swc by Molmil
IC2B model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi
Descriptor: 16S ribosomal rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Coureux, P.-D, Mechulam, Y, Schmitt, E.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation.
Commun Biol, 3, 2020
1S0U
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BU of 1s0u by Molmil
eIF2gamma apo
Descriptor: Translation initiation factor 2 gamma subunit, ZINC ION
Authors:Roll-Mecak, A, Alone, P, Cao, C, Dever, T.E, Burley, S.K.
Deposit date:2004-01-04
Release date:2004-01-20
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray Structure of Translation Initiation Factor eIF2gamma: IMPLICATIONS FOR tRNA AND eIF2alpha BINDING.
J.Biol.Chem., 279, 2004
6UZ7
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BU of 6uz7 by Molmil
K.lactis 80S ribosome with p/PE tRNA and eIF5B
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
Authors:Fernandez, I.S, Huang, B.Y.
Deposit date:2019-11-14
Release date:2020-01-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6J6N
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BU of 6j6n by Molmil
Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y.
Deposit date:2019-01-15
Release date:2019-04-24
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Cell, 177, 2019
6J6Q
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BU of 6j6q by Molmil
Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
Authors:Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y.
Deposit date:2019-01-15
Release date:2019-04-24
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Cell, 177, 2019
4H9G
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BU of 4h9g by Molmil
Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket
Descriptor: 5-bromofuran-2-carboxylic acid, AMMONIUM ION, Elongation factor Tu-A, ...
Authors:Groftehauge, M.K, Therkelsen, M, Taaning, R.H, Skrydstrup, T, Morth, J.P, Nissen, P.
Deposit date:2012-09-24
Release date:2013-09-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
6LKQ
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BU of 6lkq by Molmil
The Structural Basis for Inhibition of Ribosomal Translocation by Viomycin
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Zhang, L, Wang, Y.H, Lancaster, L, Zhou, J, Noller, H.F.
Deposit date:2019-12-20
Release date:2020-05-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural basis for inhibition of ribosomal translocation by viomycin.
Proc.Natl.Acad.Sci.USA, 117, 2020
1R5N
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BU of 1r5n by Molmil
Crystal Structure Analysis of sup35 complexed with GDP
Descriptor: Eukaryotic peptide chain release factor GTP-binding subunit, GUANOSINE-5'-DIPHOSPHATE
Authors:Kong, C, Song, H.
Deposit date:2003-10-10
Release date:2004-05-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
Mol.Cell, 14, 2004
4IW3
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BU of 4iw3 by Molmil
Crystal structure of a Pseudomonas putida prolyl-4-hydroxylase (P4H) in complex with elongation factor Tu (EF-Tu)
Descriptor: Elongation factor Tu-A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Scotti, J.S, McDonough, M.A, Schofield, C.J.
Deposit date:2013-01-23
Release date:2014-01-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.697 Å)
Cite:Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
Proc.Natl.Acad.Sci.USA, 111, 2014
4KJZ
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BU of 4kjz by Molmil
Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2
Authors:Eiler, D.R, Lin, J, Steitz, T.A.
Deposit date:2013-05-04
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases.
Proc.Natl.Acad.Sci.USA, 110, 2013
1SKQ
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BU of 1skq by Molmil
The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP
Descriptor: Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Vitagliano, L, Ruggiero, A, Masullo, M, Cantiello, P, Arcari, P, Zagari, A.
Deposit date:2004-03-05
Release date:2004-07-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with magnesium and GDP.
Biochemistry, 43, 2004
6K72
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BU of 6k72 by Molmil
eIF2(aP) - eIF2B complex
Descriptor: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ...
Authors:Kashiwagi, K, Yokoyama, T, Ito, T.
Deposit date:2019-06-05
Release date:2019-07-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019

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