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3ND3
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BU of 3nd3 by Molmil
Uhelix 16-mer dsRNA
Descriptor: 5'-R(*AP*GP*AP*GP*AP*AP*GP*AP*UP*UP*UP*UP*UP*UP*UP*U)-3', POTASSIUM ION, SODIUM ION
Authors:Mooers, B.H, Singh, A.
Deposit date:2010-06-07
Release date:2011-09-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate.
Rna, 17, 2011
3ND4
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BU of 3nd4 by Molmil
Watson-Crick 16-mer dsRNA
Descriptor: 5'-R(*AP*GP*AP*GP*AP*AP*GP*AP*UP*CP*UP*UP*CP*UP*CP*U)-3', MAGNESIUM ION, POTASSIUM ION, ...
Authors:Mooers, B.H, Singh, A.
Deposit date:2010-06-07
Release date:2011-09-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.524 Å)
Cite:The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate.
Rna, 17, 2011
7WAL
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BU of 7wal by Molmil
Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) in complex with Co
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, COBALT (II) ION, ...
Authors:Sharma, V, Manickam, Y, Babbar, P, Sharma, A.
Deposit date:2021-12-14
Release date:2022-12-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
7WAK
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BU of 7wak by Molmil
Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamyl-tRNA synthetase, ...
Authors:Sharma, V, Manickam, Y, Babbar, P, Sharma, A.
Deposit date:2021-12-14
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.782 Å)
Cite:Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
7WAJ
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BU of 7waj by Molmil
Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) complexed with ATP and Co
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Sharma, V, Manickam, Y, Babbar, P, Sharma, A.
Deposit date:2021-12-14
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.254 Å)
Cite:Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
7WAO
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BU of 7wao by Molmil
Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) in complex with Mn
Descriptor: CHLORIDE ION, Glutamyl-tRNA synthetase, MANGANESE (II) ION
Authors:Sharma, V, Manickam, Y, Babbar, P, Sharma, A.
Deposit date:2021-12-14
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.582 Å)
Cite:Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
7WAI
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BU of 7wai by Molmil
Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS)
Descriptor: CHLORIDE ION, Glutamyl-tRNA synthetase
Authors:Sharma, V, Manickam, Y, Harlos, K, Sharma, A.
Deposit date:2021-12-14
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
6DCL
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BU of 6dcl by Molmil
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
Descriptor: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
Authors:Kooshapur, H, Sattler, M.
Deposit date:2018-05-07
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
7WRS
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BU of 7wrs by Molmil
Crystal structure of the chicken isoleucyl-tRNA synthetase 1 (IARS1) UNE-I complexed with glutamyl-tRNA synthetase 1 (EARS1)
Descriptor: Glutamyl-tRNA synthetase, Isoleucyl-tRNA synthetase
Authors:Chung, S, Cho, Y.
Deposit date:2022-01-27
Release date:2022-11-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1.
Nat Commun, 13, 2022
5UD5
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BU of 5ud5 by Molmil
Crystal structure of the tRNA binding domain of Pyrrolysyl-tRNA synthetase bound to tRNA(Pyl)
Descriptor: Pyrrolysine--tRNA ligase, RNA (70-MER), ZINC ION
Authors:Suzuki, T, Soll, D.
Deposit date:2016-12-23
Release date:2017-10-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Crystal structures reveal an elusive functional domain of pyrrolysyl-tRNA synthetase.
Nat. Chem. Biol., 13, 2017
5V6X
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BU of 5v6x by Molmil
Crystal structure of the tRNA binding domain of Pyrrolysyl-tRNA synthetase mutant (32A NTD) bound to tRNA(Pyl)
Descriptor: Pyrrolysine--tRNA ligase, RNA (70-MER), ZINC ION
Authors:Suzuki, T, Soll, D.
Deposit date:2017-03-17
Release date:2017-10-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Crystal structures reveal an elusive functional domain of pyrrolysyl-tRNA synthetase.
Nat. Chem. Biol., 13, 2017
7WRU
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BU of 7wru by Molmil
Crystal structure of the apo chicken glutamyl-tRNA synthetase 1 (EARS1)
Descriptor: Glutamyl-tRNA synthetase, MERCURY (II) ION
Authors:Chung, S, Cho, Y.
Deposit date:2022-01-27
Release date:2022-11-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1.
Nat Commun, 13, 2022
3VU8
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BU of 3vu8 by Molmil
Metionyl-tRNA synthetase from Thermus thermophilus complexed with methionyl-adenylate analogue
Descriptor: Methionine--tRNA ligase, N-[METHIONYL]-N'-[ADENOSYL]-DIAMINOSULFONE, ZINC ION
Authors:Konno, M, Kato-Murayama, M, Toma-Fukai, S, Uchikawa, E, Nureki, O, Yokoyama, S.
Deposit date:2012-06-22
Release date:2013-06-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The modeling of structures of specific conformation of homosysteine-AMP leading to thiolactone-formation on class Ia aminoacyl-tRNA synthetases
To be Published
7VC1
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BU of 7vc1 by Molmil
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L95 and L-proline in space group P21
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Yogavel, M, Malhotra, N, Sharma, A.
Deposit date:2021-09-01
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.
Plos Pathog., 19, 2023
7VC3
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BU of 7vc3 by Molmil
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L97 and L-proline at 1.97 A resolution
Descriptor: 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, CHLORIDE ION, ETHANOLAMINE, ...
Authors:Malhotra, N, Yogavel, M, Sharma, A.
Deposit date:2021-09-01
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.
Plos Pathog., 19, 2023
7VC2
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BU of 7vc2 by Molmil
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L96 and L-proline in space group P21
Descriptor: 1,2-ETHANEDIOL, 4-[(3S)-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(5-methoxypyridin-3-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, CHLORIDE ION, ...
Authors:Yogavel, M, Malhotra, N, Sharma, A.
Deposit date:2021-09-01
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.
Plos Pathog., 19, 2023
7WPJ
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BU of 7wpj by Molmil
Methionyl-tRNA synthetase from Staphylococcus aureus
Descriptor: 1,2-ETHANEDIOL, Methionine--tRNA ligase
Authors:Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H.
Deposit date:2022-01-24
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase.
Nucleic Acids Res., 50, 2022
7WPI
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BU of 7wpi by Molmil
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a phenylbenzimidazole inhibitor
Descriptor: 1,2-ETHANEDIOL, 2-(4-bromanyl-3-oxidanyl-phenyl)-1-[(1R)-2-[2-(2-tert-butylphenoxy)ethanoylamino]-1-(3,4-dimethoxyphenyl)ethyl]-N-methyl-benzimidazole-5-carboxamide, ACETATE ION, ...
Authors:Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H.
Deposit date:2022-01-24
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase.
Nucleic Acids Res., 50, 2022
7WPT
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BU of 7wpt by Molmil
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a fragment M2-80 and ATP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H.
Deposit date:2022-01-24
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase.
Nucleic Acids Res., 50, 2022
7WPM
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BU of 7wpm by Molmil
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a fragment and ATP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Methionine--tRNA ligase, ...
Authors:Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H.
Deposit date:2022-01-24
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase.
Nucleic Acids Res., 50, 2022
7WPK
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BU of 7wpk by Molmil
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with L-Met
Descriptor: METHIONINE, Methionine--tRNA ligase
Authors:Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H.
Deposit date:2022-01-24
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase.
Nucleic Acids Res., 50, 2022
7WPN
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BU of 7wpn by Molmil
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a phenylbenzimidazole inhibitor and ATP
Descriptor: (phenylmethyl) N-[(2R)-2-[2-(4-bromanyl-3-oxidanyl-phenyl)-5-(methylcarbamoyl)benzimidazol-1-yl]-2-(3,4-dimethoxyphenyl)ethyl]carbamate, 1,2-ETHANEDIOL, ACETIC ACID, ...
Authors:Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H.
Deposit date:2022-01-24
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase.
Nucleic Acids Res., 50, 2022
7WPX
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BU of 7wpx by Molmil
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a fragment and ATP
Descriptor: 1,2-ETHANEDIOL, 6-chloranylimidazo[2,1-b][1,3]thiazole, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H.
Deposit date:2022-01-24
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase.
Nucleic Acids Res., 50, 2022
7WQ0
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BU of 7wq0 by Molmil
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a fragment and ATP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Methionine--tRNA ligase, ...
Authors:Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H.
Deposit date:2022-01-24
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase.
Nucleic Acids Res., 50, 2022
7WPL
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BU of 7wpl by Molmil
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with ATP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Methionine--tRNA ligase
Authors:Yi, J, Cai, Z, Qiu, H, Lu, F, Chen, B, Luo, Z, Gu, Q, Xu, J, Zhou, H.
Deposit date:2022-01-24
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase.
Nucleic Acids Res., 50, 2022

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PDB entries from 2024-09-18

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