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7LEW
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BU of 7lew by Molmil
Crystal structure of UBE2G2 in complex with the UBE2G2-binding region of AUP1
Descriptor: Lipid droplet-regulating VLDL assembly factor AUP1, Ubiquitin-conjugating enzyme E2 G2
Authors:Liang, Y.-H, Smith, C.E, Tsai, Y.C, Weissman, A.M, Ji, X.
Deposit date:2021-01-15
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.736 Å)
Cite:A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation.
Plos Biol., 19, 2021
2MT6
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BU of 2mt6 by Molmil
Solution structure of the human ubiquitin conjugating enzyme Ube2w
Descriptor: Ubiquitin-conjugating enzyme E2 W
Authors:Vittal, V, Shi, L, Wenzel, D.M, Brzovic, P.S, Klevit, R.E.
Deposit date:2014-08-14
Release date:2014-11-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Intrinsic disorder drives N-terminal ubiquitination by Ube2w.
Nat.Chem.Biol., 11, 2015
2Z5D
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BU of 2z5d by Molmil
Human ubiquitin-conjugating enzyme E2 H
Descriptor: SODIUM ION, Ubiquitin-conjugating enzyme E2 H
Authors:Bochkarev, A, Cui, H, Walker, J.R, Newman, E.M, Mackenzie, F, Battaile, K.P, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-06
Release date:2007-10-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
MOL.CELL PROTEOMICS, 11, 2012
2Y4W
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BU of 2y4w by Molmil
Solution structure of human ubiquitin conjugating enzyme Rad6b
Descriptor: UBIQUITIN-CONJUGATING ENZYME E2 B
Authors:Huang, A, Hibbert, R.G, deJong, R.N, Das, D, Sixma, T.K, Boelens, R.
Deposit date:2011-01-11
Release date:2011-05-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Symmetry and Asymmetry of the Ring-Ring Dimer of Rad18
J.Mol.Biol., 410, 2011
2OB4
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BU of 2ob4 by Molmil
Human Ubiquitin-Conjugating Enzyme CDC34
Descriptor: Ubiquitin-conjugating enzyme E2-32 kDa complementing
Authors:Neculai, D, Avvakumov, G.V, Xue, S, Walker, J.R, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Sicheri, F, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2006-12-18
Release date:2006-12-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2ONU
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BU of 2onu by Molmil
Plasmodium falciparum ubiquitin conjugating enzyme PF10_0330, putative homologue of human UBE2H
Descriptor: TETRAETHYLENE GLYCOL, Ubiquitin-conjugating enzyme, putative
Authors:Dong, A, Lew, J, Lin, L, Hassanali, A, Zhao, Y, Senisterra, G, Wasney, G, Vedadi, M, Kozieradzki, I, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Hui, R, Brokx, S.J, Structural Genomics Consortium (SGC)
Deposit date:2007-01-24
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Plasmodium falciparum ubiquitin conjugating enzyme PF10_0330, putative homologue of human UBE2H
To be Published
3BZH
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BU of 3bzh by Molmil
Crystal structure of human ubiquitin-conjugating enzyme E2 E1
Descriptor: GLYCEROL, Ubiquitin-conjugating enzyme E2 E1
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-01-18
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2Q0V
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BU of 2q0v by Molmil
Crystal structure of ubiquitin conjugating enzyme E2, putative, from Plasmodium falciparum
Descriptor: PHOSPHATE ION, Ubiquitin-conjugating enzyme E2, putative
Authors:Wernimont, A.K, Lew, J, Hassanali, A, Lin, L, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC)
Deposit date:2007-05-22
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of ubiquitin conjugating enzyme E2, putative, from Plasmodium falciparum.
To be Published
7YW1
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BU of 7yw1 by Molmil
crystal structure of UBE2O
Descriptor: (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O
Authors:Fu, Z, Zhu, W, Huang, H.
Deposit date:2022-08-20
Release date:2023-08-30
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:crystal structure of UBE2O
To Be Published
2HLW
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BU of 2hlw by Molmil
Solution Structure of the Human Ubiquitin-conjugating Enzyme Variant Uev1a
Descriptor: Ubiquitin-conjugating enzyme E2 variant 1
Authors:Hau, D.D, Lewis, M.J, Saltibus, L.F, Pastushok, L, Xiao, W, Spyracopoulos, L.
Deposit date:2006-07-10
Release date:2006-09-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure and interactions of the ubiquitin-conjugating enzyme variant human uev1a: implications for enzymatic synthesis of polyubiquitin chains(,).
Biochemistry, 45, 2006
2FO3
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BU of 2fo3 by Molmil
Plasmodium vivax ubiquitin conjugating enzyme E2
Descriptor: Ubiquitin-conjugating enzyme
Authors:Dong, A, Zhao, Y, Lew, J, Kozieradski, I, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Bochkarev, A, Qiu, W, Structural Genomics Consortium (SGC)
Deposit date:2006-01-12
Release date:2006-01-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2H2Y
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BU of 2h2y by Molmil
Crystal structure of ubiquitin conjugating enzyme E2 from plasmodium falciparum
Descriptor: Ubiquitin-conjugating enzyme
Authors:Qiu, W, Dong, A, Zhao, Y, Lew, J, Kozieradski, I, Sundararajan, E, Melone, M, Wasney, G, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
Deposit date:2006-05-19
Release date:2006-06-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2GJD
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BU of 2gjd by Molmil
Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress
Descriptor: Ubiquitin-conjugating enzyme E2-18 kDa
Authors:van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A.
Deposit date:2006-03-30
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress.
Mol.Cell.Biol., 26, 2006
8JVE
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BU of 8jve by Molmil
Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer
Descriptor: 1,2-ETHANEDIOL, 1-(3-methoxyphenyl)-1,2,3,4-tetrazole, Ubiquitin-conjugating enzyme E2 T
Authors:Anantharajan, J, Baburajendran, N.
Deposit date:2023-06-28
Release date:2023-11-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer.
Biochem.Biophys.Res.Commun., 689, 2023
8JVL
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BU of 8jvl by Molmil
Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer
Descriptor: 1,2-ETHANEDIOL, 1-(4-methoxyphenyl)-1,2,3,4-tetrazole, Ubiquitin-conjugating enzyme E2 T
Authors:Anantharajan, J, Baburajendran, N.
Deposit date:2023-06-28
Release date:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Identification and characterization of inhibitors covalently modifying catalytic cysteine of UBE2T and blocking ubiquitin transfer.
Biochem.Biophys.Res.Commun., 689, 2023
8JVD
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BU of 8jvd by Molmil
Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening
Descriptor: 5-fluoranyl-1,3-benzoxazol-2-amine, Ubiquitin-conjugating enzyme E2 T
Authors:Anantharajan, J, Baburajendran, N.
Deposit date:2023-06-28
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening.
Protein Sci., 33, 2024
8JUC
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BU of 8juc by Molmil
Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening
Descriptor: 1,2-ETHANEDIOL, 7-methyl-2-(trifluoromethyl)-3~{H}-[1,2,4]triazolo[1,5-a]pyridin-5-one, Ubiquitin-conjugating enzyme E2 T
Authors:Anantharajan, J, Baburajendran, N.
Deposit date:2023-06-26
Release date:2024-02-28
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Identification of small-molecule binding sites of a ubiquitin-conjugating enzyme-UBE2T through fragment-based screening.
Protein Sci., 33, 2024
2CYX
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BU of 2cyx by Molmil
Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)
Descriptor: Ubiquitin-conjugating enzyme E2 G2
Authors:Yoshikawa, S, Arai, R, Murayama, K, Imai, Y, Takahashi, R, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-08
Release date:2006-04-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)
Acta Crystallogr.,Sect.F, 62, 2006
2C4P
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BU of 2c4p by Molmil
Crystal structure of human ubiquitin-conjugating enzyme UbcH5A
Descriptor: UBIQUITIN-CONJUGATING ENZYME E2 D1
Authors:Dodd, R.B, Read, R.J.
Deposit date:2005-10-21
Release date:2006-11-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structures of Two Human Ubiquitin-Conjugating Enzymes from Twinned Crystals
To be Published
2BEP
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BU of 2bep by Molmil
Crystal structure of ubiquitin conjugating enzyme E2-25K
Descriptor: BETA-MERCAPTOETHANOL, UBIQUITIN-CONJUGATING ENZYME E2-25 KDA
Authors:Pichler, A, Knipscheer, P, Oberhofer, E, Van Dijk, W.J, Korner, R, Velgaard Olsen, J, Jentsch, S, Melchior, F, Sixma, T.K.
Deposit date:2004-11-29
Release date:2005-02-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K
Nat.Struct.Mol.Biol., 12, 2005
2EDI
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BU of 2edi by Molmil
Solution structure of the UQ_con domain from human NEDD8-conjugating enzyme NCE2
Descriptor: NEDD8-conjugating enzyme UBE2F
Authors:Endo, H, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-14
Release date:2007-08-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the UQ_con domain from human NEDD8-conjugating enzyme NCE2
To be Published
2AWF
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BU of 2awf by Molmil
Structure of human Ubiquitin-conjugating enzyme E2 G1
Descriptor: Ubiquitin-conjugating enzyme E2 G1
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty, P, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2005-09-01
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2CLW
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BU of 2clw by Molmil
Crystal structure of human ubiquitin-conjugating enzyme UbcH5B
Descriptor: GLYCEROL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E2 D2
Authors:Dodd, R.B, Read, R.J.
Deposit date:2006-05-02
Release date:2007-06-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.945 Å)
Cite:Structures of Two Human Ubiquitin-Conjugating Enzymes from Twinned Crystals
To be Published
2E2C
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BU of 2e2c by Molmil
E2-C, AN UBIQUITIN CONJUGATING ENZYME REQUIRED FOR THE DESTRUCTION OF MITOTIC CYCLINS
Descriptor: UBIQUITIN CONJUGATING ENZYME
Authors:Jiang, F, Basavappa, R.
Deposit date:1999-01-19
Release date:1999-01-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the cyclin-specific ubiquitin-conjugating enzyme from clam, E2-C, at 2.0 A resolution.
Biochemistry, 38, 1999
2ESK
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BU of 2esk by Molmil
Human Ubiquitin-Conjugating Enzyme (E2) UbcH5b, wild-type
Descriptor: Ubiquitin-conjugating enzyme E2 D2
Authors:Ozkan, E, Yu, H, Deisenhofer, J.
Deposit date:2005-10-26
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases
Proc.Natl.Acad.Sci.Usa, 102, 2005

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