3AQI
| H240A variant of human ferrochelatase | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | Authors: | Lanzilotta, W.N, Medlock, A.E, Dailey, T.A, Dailey, H.A. | Deposit date: | 2010-11-03 | Release date: | 2012-01-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | H240A variant of human ferrochelatase To be published
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2QD5
| Structure of wild type human ferrochelatase in complex with a lead-porphyrin compound | Descriptor: | ACETIC ACID, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Meldock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | Deposit date: | 2007-06-20 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
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2QD4
| Wild type human ferrochelatase crystallized with MnCl2 | Descriptor: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | Deposit date: | 2007-06-20 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
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2QD3
| Wild type human ferrochelatase crystallized with ammonium sulfate | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | Authors: | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | Deposit date: | 2007-06-20 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
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2QD2
| F110A variant of human ferrochelatase with protoheme bound | Descriptor: | BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilota, W.N. | Deposit date: | 2007-06-20 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
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2QD1
| 2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | Authors: | Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N. | Deposit date: | 2007-06-20 | Release date: | 2007-10-30 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase. J.Mol.Biol., 373, 2007
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2Q3J
| Crystal structure of the His183Ala variant of Bacillus subtilis ferrochelatase in complex with N-Methyl Mesoporphyrin | Descriptor: | Ferrochelatase, MAGNESIUM ION, N-METHYL PROTOPORPHYRIN IX 2,4-DISULFONIC ACID | Authors: | Karlberg, T, Thorvaldsen, O.H, Al-Karadaghi, S. | Deposit date: | 2007-05-30 | Release date: | 2008-04-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Porphyrin binding and distortion and substrate specificity in the ferrochelatase reaction: the role of active site residues J.Mol.Biol., 378, 2008
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2Q2O
| Crystal structure of H183C Bacillus subtilis ferrochelatase in complex with deuteroporphyrin IX 2,4-disulfonic acid dihydrochloride | Descriptor: | Ferrochelatase, MAGNESIUM ION, PROTOPORPHYRIN IX 2,4-DISULFONIC ACID | Authors: | Karlberg, T, Thorvaldsen, O.H, Al-Karadaghi, S. | Deposit date: | 2007-05-29 | Release date: | 2008-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Porphyrin binding and distortion and substrate specificity in the ferrochelatase reaction: the role of active site residues J.Mol.Biol., 378, 2008
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2Q2N
| Crystal structure of Bacillus subtilis ferrochelatase in complex with deuteroporphyrin IX 2,4-disulfonic acid dihydrochloride | Descriptor: | Ferrochelatase, MAGNESIUM ION, PROTOPORPHYRIN IX 2,4-DISULFONIC ACID | Authors: | Karlberg, T, Thorvaldsen, O.H, Al-Karadaghi, S. | Deposit date: | 2007-05-29 | Release date: | 2008-04-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Porphyrin binding and distortion and substrate specificity in the ferrochelatase reaction: the role of active site residues J.Mol.Biol., 378, 2008
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2PO7
| Crystal structure of human ferrochelatase mutant with His 341 replaced by Cys | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | Authors: | Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, W, Burden, A, Dailey, T.A, Rose, J.P. | Deposit date: | 2007-04-25 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis. Biochemistry, 46, 2007
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2PO5
| Crystal structure of human ferrochelatase mutant with His 263 replaced by Cys | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | Authors: | Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, A.E.W, Burden, A, Dailey, T.A, Rose, J.P. | Deposit date: | 2007-04-25 | Release date: | 2007-10-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis Biochemistry, 46, 2007
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2PNJ
| Crystal structure of human ferrochelatase mutant with Phe 337 replaced by Ala | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | Authors: | Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, W, Burden, A.E, Dailey, T.A, Rose, J.P. | Deposit date: | 2007-04-24 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis Biochemistry, 46, 2007
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2HRE
| Structure of human ferrochelatase variant E343K with protoporphyrin IX bound | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | Authors: | Medlock, A, Swartz, L, Dailey, T.A, Dailey, H.A, Lanzilotta, W.N. | Deposit date: | 2006-07-20 | Release date: | 2007-03-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Substrate interactions with human ferrochelatase Proc.Natl.Acad.Sci.Usa, 104, 2007
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2HRC
| 1.7 angstrom structure of human ferrochelatase variant R115L | Descriptor: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Medlock, A, Swartz, L, Dailey, T.A, Dailey, H.A, Lanzilotta, W.N. | Deposit date: | 2006-07-20 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Substrate interactions with human ferrochelatase Proc.Natl.Acad.Sci.Usa, 104, 2007
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2HK6
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2H1W
| Crystal structure of the His183Ala mutant variant of Bacillus subtilis ferrochelatase | Descriptor: | FE (II) ION, Ferrochelatase, MAGNESIUM ION | Authors: | Hansson, M.D, Karlberg, T, Arys Rahardja, M, Al-Karadaghi, S, Hansson, M. | Deposit date: | 2006-05-17 | Release date: | 2007-01-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Amino Acid Residues His183 and Glu264 in Bacillus subtilis Ferrochelatase Direct and Facilitate the Insertion of Metal Ion into Protoporphyrin IX Biochemistry, 46, 2007
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2H1V
| Crystal structure of the Lys87Ala mutant variant of Bacillus subtilis ferrochelatase | Descriptor: | Ferrochelatase, MAGNESIUM ION | Authors: | Hansson, M.D, Karlberg, T, Arys Rahardja, M, Al-Karadaghi, S, Hansson, M. | Deposit date: | 2006-05-17 | Release date: | 2007-01-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Amino Acid Residues His183 and Glu264 in Bacillus subtilis Ferrochelatase Direct and Facilitate the Insertion of Metal Ion into Protoporphyrin IX Biochemistry, 46, 2007
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2C8J
| CRYSTAL STRUCTURE OF ferrochelatase HemH-1 from Bacillus anthracis, str. Ames | Descriptor: | FERROCHELATASE 1 | Authors: | Muller, A, Lebedev, A.A, Moroz, O.V, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S. | Deposit date: | 2005-12-05 | Release date: | 2007-05-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of Ferrochelatase Hemh-1 from Bacillus Anthracis, Str. Ames To be Published
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2AC4
| Crystal structure of the His183Cys mutant variant of Bacillus subtilis Ferrochelatase | Descriptor: | Ferrochelatase | Authors: | Shipovskov, S, Karlberg, T, Fodje, M, Hansson, M.D, Ferreira, G.C, Hansson, M, Reimann, C.T, Al-Karadaghi, S. | Deposit date: | 2005-07-18 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism. J.Mol.Biol., 352, 2005
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2AC2
| Crystal structure of the Tyr13Phe mutant variant of Bacillus subtilis Ferrochelatase with Zn(2+) bound at the active site | Descriptor: | Ferrochelatase, ZINC ION | Authors: | Shipovskov, S, Karlberg, T, Fodje, M, Hansson, M.D, Ferreira, G.C, Hansson, M, Reimann, C.T, Al-Karadaghi, S. | Deposit date: | 2005-07-18 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism. J.Mol.Biol., 352, 2005
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1N0I
| Crystal Structure of Ferrochelatase with Cadmium bound at active site | Descriptor: | CADMIUM ION, CHLORIDE ION, Ferrochelatase, ... | Authors: | Lecerof, D, Fodje, M.N, Leon, R.A, Olsson, U, Hansson, A, Sigfridsson, E, Ryde, U, Hansson, M, Al-Karadaghi, S. | Deposit date: | 2002-10-14 | Release date: | 2003-05-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Metal binding to Bacillus subtilis ferrochelatase and interaction between metal sites J.Biol.Inorg.Chem., 8, 2003
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1LD3
| Crystal Structure of B. subilis ferrochelatase with Zn(2+) bound at the active site. | Descriptor: | Ferrochelatase, ZINC ION | Authors: | Lecerof, D, Fodje, M.N, Leon, R.A, Olsson, U, Hansson, A, Sigfridsson, E, Ryde, U, Hansson, M, Al-Karadaghi, S. | Deposit date: | 2002-04-08 | Release date: | 2003-05-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Metal binding to Bacillus subtilis ferrochelatase and interaction between metal sites J.Biol.Inorg.Chem., 8, 2003
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1LBQ
| The crystal structure of Saccharomyces cerevisiae ferrochelatase | Descriptor: | Ferrochelatase | Authors: | Karlberg, T, Lecerof, D, Gora, M, Silvegren, G, Labbe-Bois, R, Hansson, M, Al-Karadaghi, S. | Deposit date: | 2002-04-04 | Release date: | 2002-11-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Metal binding to Saccharomyces cerevisiae ferrochelatase Biochemistry, 41, 2002
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1L8X
| Crystal Structure of Ferrochelatase from the Yeast, Saccharomyces cerevisiae, with Cobalt(II) as the Substrate Ion | Descriptor: | COBALT (II) ION, Ferrochelatase | Authors: | Karlberg, T, Lecerof, D, Gora, M, Silvegren, G, Labbe-Bois, R, Hansson, M, Al-Karadaghi, S. | Deposit date: | 2002-03-22 | Release date: | 2002-11-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Metal Binding to Saccharomyces cerevisiae Ferrochelatase Biochemistry, 41, 2002
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1HRK
| CRYSTAL STRUCTURE OF HUMAN FERROCHELATASE | Descriptor: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, FERROCHELATASE | Authors: | Wu, C.K, Dailey, H.A, Rose, J.P, Burden, A, Sellers, V.M, Wang, B.-C. | Deposit date: | 2000-12-21 | Release date: | 2001-06-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis. Nat.Struct.Biol., 8, 2001
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