4UIA
 
 | | Crystal structure of 3a in complex with tafCPB | | Descriptor: | (2S)-6-azanyl-2-[[(2R)-3-cyclohexyl-1-(3-methylbutylamino)-1-oxidanylidene-propan-2-yl]carbamoylamino]hexanoic acid, CARBOXYPEPTIDASE B, ZINC ION | | Authors: | Halland, N, Broenstrup, M, Czech, J, Czechtizky, W, Evers, A, Follmann, M, Kohlmann, M, Schiell, M, Kurz, M, Schreuder, H.A, Kallus, C. | | Deposit date: | 2015-03-27 | | Release date: | 2015-06-03 | | Last modified: | 2015-08-26 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (Tafia) from Natural Product Anabaenopeptin.
J.Med.Chem., 58, 2015
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4UEE
 | | Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Ala-Y(PO2CH2)-homoPhe-OH | | Descriptor: | (2S)-2-{[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, CARBOXYPEPTIDASE A1, ZINC ION | | Authors: | Gallego, P, Covaleda, G, Costenaro, L, Devel, L, Dive, V, Aviles, F.X, Reverter, D. | | Deposit date: | 2014-12-17 | | Release date: | 2016-01-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors
To be Published
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4UEZ
 | | Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH | | Descriptor: | (2S)-3-[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]-2-phenylethyl}(hydroxy)phosphoryl]-2-benzylpropanoic acid, HUMAN CARBOXYPEPTIDASE A1, ZINC ION | | Authors: | Gallego, P, Covaleda, G, Costenaro, L, Devel, L, Dive, V, Aviles, F.X, Reverter, D. | | Deposit date: | 2014-12-22 | | Release date: | 2016-01-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors
To be Published
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6GO2
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4F8Z
 | | Carboxypeptidase T with Boc-Leu | | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | | Deposit date: | 2012-05-18 | | Release date: | 2013-05-22 | | Last modified: | 2015-09-30 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Three-dimensional structure of carboxypeptidase T from Thermoactinomyces vulgaris in complex with N-BOC-L-leucine.
Biochemistry Mosc., 78, 2013
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1OBR
 | | CARBOXYPEPTIDASE T | | Descriptor: | CALCIUM ION, CARBOXYPEPTIDASE T, SULFATE ION, ... | | Authors: | Teplyakov, A, Polyakov, K, Obmolova, G, Osterman, A. | | Deposit date: | 1996-06-22 | | Release date: | 1997-01-11 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris.
Eur.J.Biochem., 208, 1992
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4GM5
 | | Carboxypeptidase T with Sulphamoil Arginine | | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | | Authors: | Kuznetsov, S.A, Timofeev, V.I, Akparov, V.K, Kuranova, I.P. | | Deposit date: | 2012-08-15 | | Release date: | 2013-08-21 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Carboxypeptidase T with Sulphamoil Arginine
To be Published
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4IAV
 | | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with N-Sulfamoyl-L-phenylalanine | | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | | Deposit date: | 2012-12-07 | | Release date: | 2013-12-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with N-Sulfamoyl-L-phenylalanine
TO BE PUBLISHED
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4IHM
 | | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris | | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | | Deposit date: | 2012-12-19 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris
To be published
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4IK2
 | | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with N-BOC-L-Leu | | Descriptor: | CALCIUM ION, Carboxypeptidase T, N-(tert-butoxycarbonyl)-L-leucine, ... | | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | | Deposit date: | 2012-12-25 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | G215S, A251G, T257A, D260G, T262D mutant of carboxypeptidase T from Thermoactinomyces vulgaris with N-BOC-L-Leu
To be published
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3PRT
 | | Mutant of the Carboxypeptidase T | | Descriptor: | CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... | | Authors: | Timofeev, V.I, Akparov, V.K, Grishin, A.M, Kuranova, I.P. | | Deposit date: | 2010-11-30 | | Release date: | 2011-11-30 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: |
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3QNV
 | | Carboxypeptidase T | | Descriptor: | Carboxypeptidase T, GLYCEROL, SULFATE ION, ... | | Authors: | Timofeev, V.I, Akparov, V.K, Kuranova, I.P. | | Deposit date: | 2011-02-09 | | Release date: | 2012-02-15 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Three-dimensional structure of recombinant carboxypeptidase T from Thermoactinomyces vulgaris without calcium ions
Crystallography Reports, 56, 2011
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1HDQ
 | | Crystal structure of bovine pancreatic carboxypeptidase A complexed with D-N-hydroxyaminocarbonyl phenylalanine at 2.3 A | | Descriptor: | CARBOXYPEPTIDASE A, D-[(N-HYDROXYAMINO)CARBONYL]PHENYLALANINE, ZINC ION | | Authors: | Cho, J.H, Ha, N.-C, Chung, S.J, Kim, D.H, Choi, K.Y, Oh, B.-H. | | Deposit date: | 2000-11-17 | | Release date: | 2001-11-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Insight Into the Stereochemistry in the Inhibition of Carboxypeptidase a with N-(Hydroxyaminocarbonyl)Phenylalanine: Binding Modes of an Enantiomeric Pair of the Inhibitor to Carboxypeptidase A
Bioorg.Med.Chem., 10, 2002
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1IY7
 | | Crystal Structure of CPA and sulfamide-based inhibitor complex | | Descriptor: | Carboxypeptidase A, PHENYLALANINE-N-SULFONAMIDE, ZINC ION | | Authors: | Kim, S.J, Woo, J.R, Park, J.D, Kim, D.H, Ryu, S.E. | | Deposit date: | 2002-07-24 | | Release date: | 2003-01-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Sulfamide-Based Inhibitors for Carboxypeptidase A. Novel Type Transition State Analogue Inhibitors for Zinc Proteases
J.Med.Chem., 45, 2002
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5HXD
 | | Crystal structure of murein-tripeptide amidase MpaA from Escherichia coli O157 | | Descriptor: | CACODYLATE ION, Protein MpaA, ZINC ION | | Authors: | Ma, Y, Bai, G, Zhang, X, Zhao, J, Yuan, Z, Kang, X, Li, Z, Mu, S, Liu, X. | | Deposit date: | 2016-01-30 | | Release date: | 2017-02-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of Murein-Tripeptide Amidase MpaA from Escherichia coli O157 at 2.6 angstrom Resolution
Protein Pept.Lett., 24, 2017
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5J1Q
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5JC6
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3V38
 | | Carboxypeptidase T mutant L254N | | Descriptor: | Carboxypeptidase T, GLYCEROL, SULFATE ION, ... | | Authors: | Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. | | Deposit date: | 2011-12-13 | | Release date: | 2012-12-19 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Carboxypeptidase T mutant L254N
TO BE PUBLISHED
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3V7Z
 | | Carboxypeptidase T with GEMSA | | Descriptor: | (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, CALCIUM ION, Carboxypeptidase T, ... | | Authors: | Kuznetsov, S.A, Timofeev, V.I, Akparov, V.K, Kuranova, I.P. | | Deposit date: | 2011-12-22 | | Release date: | 2012-12-26 | | Last modified: | 2015-09-30 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Structural insights into the broad substrate specificity of carboxypeptidase T from Thermoactinomyces vulgaris.
Febs J., 282, 2015
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3WC7
 | | Carboxypeptidase B in complex with EF6265 | | Descriptor: | (2S)-7-amino-2-{[(R)-hydroxy{(1R)-2-methyl-1-[(3-phenylpropanoyl)amino]propyl}phosphoryl]methyl}heptanoic acid, Carboxypeptidase B, ZINC ION | | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | | Deposit date: | 2013-05-24 | | Release date: | 2013-10-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme.
J.Med.Chem., 56, 2013
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3WAB
 | | Carboxypeptidase B in complex with DD2 | | Descriptor: | (2R)-7-amino-2-(sulfanylmethyl)heptanoic acid, CACODYLATE ION, Carboxypeptidase B, ... | | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | | Deposit date: | 2013-05-01 | | Release date: | 2013-10-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.154 Å) | | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme.
J.Med.Chem., 56, 2013
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3WC5
 | | Carboxypeptidase B in complex with DD9 | | Descriptor: | (2R)-7-amino-2-(selanylmethyl)heptanoic acid, CACODYLATE ION, Carboxypeptidase B, ... | | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | | Deposit date: | 2013-05-24 | | Release date: | 2013-10-02 | | Last modified: | 2022-08-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme.
J.Med.Chem., 56, 2013
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1M4L
 | | STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION | | Descriptor: | CARBOXYPEPTIDASE A, ZINC ION | | Authors: | Kilshtain-Vardi, A, Glick, M, Greenblatt, H.M, Goldblum, A, Shoham, G. | | Deposit date: | 2002-07-03 | | Release date: | 2003-01-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Refined structure of bovine carboxypeptidase A at 1.25 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
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3WC6
 | | Carboxypeptidase B in complex with 2nd zinc | | Descriptor: | ACETATE ION, Carboxypeptidase B, ZINC ION | | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | | Deposit date: | 2013-05-24 | | Release date: | 2013-10-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme.
J.Med.Chem., 56, 2013
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3CPA
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