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5HCR
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BU of 5hcr by Molmil
Crystal structure of antimicrobial peptide Oncocin 10wt bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A.
Deposit date:2016-01-04
Release date:2016-04-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Nucleic Acids Res., 44, 2016
5HAU
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BU of 5hau by Molmil
Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A.
Deposit date:2015-12-30
Release date:2016-04-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Nucleic Acids Res., 44, 2016
5H5U
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BU of 5h5u by Molmil
Mechanistic insights into the alternative translation termination by ArfA and RF2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ma, C, Kurita, D, Li, N, Chen, Y, Himeno, H, Gao, N.
Deposit date:2016-11-09
Release date:2017-01-25
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanistic insights into the alternative translation termination by ArfA and RF2
Nature, 541, 2017
5IB7
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BU of 5ib7 by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2016-02-22
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
5IMQ
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BU of 5imq by Molmil
Structure of ribosome bound to cofactor at 3.8 angstrom resolution
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G.
Deposit date:2016-03-06
Release date:2016-05-18
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome
J.Biol.Chem., 291, 2016
5FDV
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BU of 5fdv by Molmil
Crystal structure of the Pyrrhocoricin antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Seefeldt, A.C, Graf, M, Perebaskine, N, Nguyen, F, Arenz, S, Mardirossian, M, Scocchi, M, Wilson, D.N, Innis, C.A.
Deposit date:2015-12-16
Release date:2016-01-27
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
5IBB
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BU of 5ibb by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2016-02-22
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
5I4L
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BU of 5i4l by Molmil
Crystal structure of Amicoumacin A bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Prokhorova, I.V, Yusupova, G, Yusupov, M.
Deposit date:2016-02-12
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome.
Sci Rep, 6, 2016
5HCP
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BU of 5hcp by Molmil
Crystal structure of antimicrobial peptide Metalnikowin bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A.
Deposit date:2016-01-04
Release date:2016-04-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Nucleic Acids Res., 44, 2016
5HCQ
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BU of 5hcq by Molmil
Crystal structure of antimicrobial peptide Oncocin d15-19 bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A.
Deposit date:2016-01-04
Release date:2016-04-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Nucleic Acids Res., 44, 2016
5IT7
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BU of 5it7 by Molmil
Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2
Descriptor: (2S)-1-amino-N,N,N-trimethyl-1-oxobutan-2-aminium, 18S ribosomal RNA, 25S ribosomal RNA, ...
Authors:Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S.
Deposit date:2016-03-16
Release date:2016-05-18
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife, 5, 2016
5HD1
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BU of 5hd1 by Molmil
Crystal structure of antimicrobial peptide Pyrrhocoricin bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A.
Deposit date:2016-01-04
Release date:2016-04-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Nucleic Acids Res., 44, 2016
5IB8
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BU of 5ib8 by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNALys with U-G mismatch in the A-site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2016-02-22
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
5IT9
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BU of 5it9 by Molmil
Structure of the yeast Kluyveromyces lactis small ribosomal subunit in complex with the cricket paralysis virus IRES.
Descriptor: 18S ribosomal RNA, Cricket paralysis virus IRES RNA, MAGNESIUM ION, ...
Authors:Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S.
Deposit date:2016-03-16
Release date:2016-05-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife, 5, 2016
5IT8
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BU of 5it8 by Molmil
High-resolution structure of the Escherichia coli ribosome
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-03-16
Release date:2016-07-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IWA
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BU of 5iwa by Molmil
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic
Descriptor: (2S,3S)-2-{[(2S)-3-(2-amino-1H-imidazol-5-yl)-2-{[(2S,4S)-5-(carbamoyloxy)-4-hydroxy-2-({[(2S,3S)-3-hydroxypiperidin-2-yl]carbonyl}amino)pentanoyl]amino}propanoyl]amino}-3-(2-chloro-1H-imidazol-5-yl)-3-hydroxypropanoic acid, 16S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Chieko, N, Masahito, K, Takemoto, C, Yokoyama, S, Connell, S.R, Fucini, P.
Deposit date:2016-03-22
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J88
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BU of 5j88 by Molmil
Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-04-07
Release date:2016-07-06
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J4C
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BU of 5j4c by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S.
Deposit date:2016-03-31
Release date:2016-04-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
5J30
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BU of 5j30 by Molmil
Thermus thermophilus 70S termination complex containing E. coli RF1
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Dunham, C.M.
Deposit date:2016-03-30
Release date:2016-10-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
5J8B
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BU of 5j8b by Molmil
Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Gagnon, M.G, Lin, J, Steitz, T.A.
Deposit date:2016-04-07
Release date:2016-05-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Elongation factor 4 remodels the A-site tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
8Q87
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BU of 8q87 by Molmil
Structure of the G. gallus 80S rotated ribosome in complex with eEF2 and SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Nurullina, L, Jenner, L, Yusupov, M.
Deposit date:2023-08-18
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells
To Be Published
8Q7Z
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BU of 8q7z by Molmil
Structure of the G. gallus 80S non-rotated ribosome
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
Authors:Nurullina, L, Jenner, L, Yusupov, M.
Deposit date:2023-08-17
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells
To Be Published
8T4S
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BU of 8t4s by Molmil
MERS-CoV Nsp1 protein bound to the Human 40S Ribosomal subunit
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Devarkar, S.C, Xiong, Y.
Deposit date:2023-06-09
Release date:2023-10-04
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis for translation inhibition by MERS-CoV Nsp1 reveals a conserved mechanism for betacoronaviruses.
Cell Rep, 42, 2023
6QZP
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BU of 6qzp by Molmil
High-resolution cryo-EM structure of the human 80S ribosome
Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA (1740-MER), 28S rRNA (3773-MER), ...
Authors:Natchiar, S.K, Myasnikov, A.G, Kratzat, H, Hazemann, I, Klaholz, B.P.
Deposit date:2019-03-12
Release date:2019-04-24
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Visualization of chemical modifications in the human 80S ribosome structure.
Nature, 551, 2017
8T5H
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BU of 8t5h by Molmil
Cryo-EM studies of the interplay between uS2 ribosomal protein and leaderless mRNA during bacterial translation initiation
Descriptor: 16S, 23S, 30S ribosomal protein S10, ...
Authors:Bhattacharjee, S, Gottesman, M.E, Frank, J.
Deposit date:2023-06-13
Release date:2024-08-28
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:How Dedicated Ribosomes Translate a Leaderless mRNA.
J.Mol.Biol., 436, 2024

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PDB entries from 2024-09-18

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