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5GOT
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BU of 5got by Molmil
Crystal structure of SP-PTP, low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes
Descriptor: CHLORIDE ION, Low molecular weight phosphotyrosine phosphatase family protein
Authors:Ku, B, Keum, C.W, KIim, S.J.
Deposit date:2016-07-29
Release date:2016-09-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Crystal structure of SP-PTP, a low molecular weight protein tyrosine phosphatase from Streptococcus pyogenes
Biochem.Biophys.Res.Commun., 478, 2016
5PNT
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BU of 5pnt by Molmil
CRYSTAL STRUCTURE OF A HUMAN LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE. IMPLICATIONS FOR SUBSTRATE SPECIFICITY
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE
Authors:Zhang, M, Stauffacher, C, Lin, D, Vanetten, R.
Deposit date:1998-04-29
Release date:1998-10-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. Implications for substrate specificity.
J.Biol.Chem., 273, 1998
7KH8
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BU of 7kh8 by Molmil
Human LMPTP in complex with inhibitor
Descriptor: 3-[(2,6-dichlorophenyl)methyl]-8-(2-methylphenyl)-3H-purin-6-amine, Low molecular weight phosphotyrosine protein phosphatase, NITRATE ION
Authors:Stanford, S.M, Diaz, M.A, Ardecky, R.J, Zou, J, Roosild, T, Holmes, Z.J, Hedrick, M.P, Rodiles, S, Santelli, E, Chung, T.D.Y, Jackson, M.R, Bottini, N, Pinkerton, A.B.
Deposit date:2020-10-20
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase.
J.Med.Chem., 64, 2021
4LRQ
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BU of 4lrq by Molmil
Crystal structure of a Low Molecular Weight Phosphotyrosine phosphatase from Vibrio choleraeO395
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Phosphotyrosine protein phosphatase, SULFATE ION
Authors:Nath, S, Banerjee, R, Sen, U.
Deposit date:2013-07-20
Release date:2014-07-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Atomic resolution crystal structure of VcLMWPTP-1 from Vibrio cholerae O395: insights into a novel mode of dimerization in the low molecular weight protein tyrosine phosphatase family.
Biochem.Biophys.Res.Commun., 450, 2014
2L17
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BU of 2l17 by Molmil
An arsenate reductase in the reduced state
Descriptor: Arsenate reductase
Authors:Yu, C, Xia, B, Jin, C.
Deposit date:2010-07-26
Release date:2011-04-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:(1)H, (13)C and (15)N resonance assignments of the arsenate reductase from Synechocystis sp. strain PCC 6803
Biomol.Nmr Assign., 5, 2011
7UW6
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BU of 7uw6 by Molmil
The co-crystal structure of low molecular weight protein tyrosine phosphatase (LMW-PTP) with a small molecule inhibitor SPAA-2
Descriptor: 2-[(1,3-benzothiazol-2-yl)amino]-2-oxoethane-1-sulfonic acid, Low molecular weight phosphotyrosine protein phosphatase
Authors:Wang, J, Zhang, Z.Y.
Deposit date:2022-05-02
Release date:2022-10-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors.
J.Med.Chem., 65, 2022
5O7B
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BU of 5o7b by Molmil
CRYSTAL STRUCTURE OF THE SLR0328 TYROSINE PHOSPHATASE WZB FROM SYNECHOCYSTIS SP. PCC 6803
Descriptor: Putative low molecular weight protein-tyrosine-phosphatase slr0328
Authors:Leite, J.P, Gales, L.
Deposit date:2017-06-08
Release date:2018-06-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.281 Å)
Cite:The role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb (Slr0328) in the production of extracellular polymeric substances (EPS) by Synechocystis PCC 6803.
Microbiologyopen, 2019
5Z3M
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BU of 5z3m by Molmil
Crystal structure of Low Molecular Weight Phosphotyrosine phosphatase (VcLMWPTP-2) from Vibrio choleraeO395
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, Phosphotyrosine protein phosphatase, ...
Authors:Chatterjee, S, Nath, S, Sen, U.
Deposit date:2018-01-08
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Vibrio cholerae LMWPTP-2 display unique surface charge and grooves around the active site: Indicative of distinctive substrate specificity and scope to design specific inhibitor.
Biochim Biophys Acta Proteins Proteom, 1867, 2019
4PIC
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BU of 4pic by Molmil
YwlE arginine phosphatase from Geobacillus stearothermophilus
Descriptor: Arginine phosphatase Ywle, PHOSPHATE ION, SULFATE ION
Authors:Clausen, T, Fuhrmann, J.
Deposit date:2014-05-08
Release date:2014-05-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Chasing phosphoarginine proteins: development of a selective enrichment method using a phosphatase trap.
Mol.Cell Proteomics, 2014
8P5N
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BU of 8p5n by Molmil
Arsenate reductase (ArsC2) from Deinococcus indicus, co-crystallized with arsenate
Descriptor: ARSENATE, GLYCEROL, Low molecular weight phosphatase family protein
Authors:Gouveia, A.G, Matias, P.M, Romao, C.V.
Deposit date:2023-05-24
Release date:2023-08-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus .
Front Microbiol, 14, 2023
8P6M
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BU of 8p6m by Molmil
Arsenate reductase (ArsC2) from Deinococcus indicus
Descriptor: Low molecular weight phosphatase family protein
Authors:Gouveia, A.G, Matias, P.M, Romao, C.V.
Deposit date:2023-05-26
Release date:2023-08-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus .
Front Microbiol, 14, 2023
4KK3
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BU of 4kk3 by Molmil
YwlE arginine phosphatase - wildtype
Descriptor: Low molecular weight protein-tyrosine-phosphatase YwlE, PHOSPHATE ION
Authors:Fuhrmann, J, Clausen, T.
Deposit date:2013-05-05
Release date:2013-07-03
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria.
Cell Rep, 3, 2013
4KK4
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BU of 4kk4 by Molmil
YwlE arginine phosphatase - C7S mutant with phosphorylated active site serine
Descriptor: Low molecular weight protein-tyrosine-phosphatase YwlE
Authors:Fuhrmann, J, Clausen, T.
Deposit date:2013-05-05
Release date:2013-07-03
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria.
Cell Rep, 3, 2013
1C0E
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BU of 1c0e by Molmil
Active Site S19A Mutant of Bovine Heart Phosphotyrosyl Phosphatase
Descriptor: PHOSPHATE ION, PROTEIN (TYROSINE PHOSPHATASE (ORTHOPHOSPHORIC MONOESTER PHOSPHOHYDROLASE))
Authors:Tabernero, L, Evans, B.N, Tishmack, P.A, Van Etten, R.L, Stauffacher, C.V.
Deposit date:1999-07-15
Release date:1999-09-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the bovine protein tyrosine phosphatase dimer reveals a potential self-regulation mechanism.
Biochemistry, 38, 1999
1BVH
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BU of 1bvh by Molmil
SOLUTION STRUCTURE OF A LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE
Descriptor: ACID PHOSPHATASE
Authors:Logan, T.M, Zhou, M.-M, Nettesheim, D.G, Meadows, R.P, Van Etten, R.L, Fesik, S.W.
Deposit date:1994-05-03
Release date:1994-07-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a low molecular weight protein tyrosine phosphatase.
Biochemistry, 33, 1994
6Y2V
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BU of 6y2v by Molmil
Crystal structure of the double mutant L13R I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP)
Descriptor: Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION, TRIETHYLENE GLYCOL
Authors:Levy, C.
Deposit date:2020-02-17
Release date:2020-07-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme.
Plos One, 15, 2020
6Y2W
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BU of 6y2w by Molmil
Crystal structure of the single mutant I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP)
Descriptor: ACETATE ION, Low molecular weight phosphotyrosine protein phosphatase
Authors:Levy, C.
Deposit date:2020-02-17
Release date:2020-07-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme.
Plos One, 15, 2020
2WJA
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BU of 2wja by Molmil
Crystal structure of the tyrosine phosphatase Wzb from Escherichia coli K30 in complex with phosphate.
Descriptor: NICKEL (II) ION, PHOSPHATE ION, PUTATIVE ACID PHOSPHATASE WZB
Authors:Huang, H, Hagelueken, G, Whitfield, C, Naismith, J.H.
Deposit date:2009-05-25
Release date:2009-07-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly.
J.Mol.Biol., 392, 2009
2WMY
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BU of 2wmy by Molmil
Crystal structure of the tyrosine phosphatase Wzb from Escherichia coli K30 in complex with sulphate.
Descriptor: NICKEL (II) ION, PUTATIVE ACID PHOSPHATASE WZB, SULFATE ION
Authors:Huang, H, Hagelueken, G, Whitfield, C, Naismith, J.H.
Deposit date:2009-07-03
Release date:2009-07-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.211 Å)
Cite:Crystal Structures of the Capsular Export Regulating Tyrosine Phosphatases Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae.
To be Published
2CWD
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BU of 2cwd by Molmil
Crystal Structure of TT1001 protein from Thermus thermophilus HB8
Descriptor: MAGNESIUM ION, low molecular weight phosphotyrosine protein phosphatase
Authors:Lokanath, N.K, Terao, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-06-20
Release date:2006-09-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of TT1001 protein from Thermus thermophilus HB8
To be Published
4Z9A
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BU of 4z9a by Molmil
Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with phenylmethanesulfonic acid
Descriptor: GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase, SULFATE ION, ...
Authors:Trivella, D.B.B, Fonseca, E.M.B, Scorsato, V, Dias, M.P, Aparicio, R.
Deposit date:2015-04-10
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates.
Bioorg.Med.Chem., 23, 2015
4Z9B
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BU of 4z9b by Molmil
Crystal structure of Low Molecular Weight Protein Tyrosine Phosphatase isoform A complexed with benzylphosphonic acid
Descriptor: Low molecular weight phosphotyrosine protein phosphatase, benzylphosphonic acid
Authors:Fonseca, E.M.B, Trivella, D.B.B, Scorsato, V, Dias, M.P, de Oliveira, F.L, Miranda, P.C.M.L, Aparicio, R.
Deposit date:2015-04-10
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates.
Bioorg.Med.Chem., 23, 2015
6U1P
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BU of 6u1p by Molmil
Crystal structure of VpsU (VC0916) from Vibrio cholerae
Descriptor: GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase
Authors:Tripathi, S.M, Schwechheimer, C, Herbert, K, Osorio, J, Yildiz, F.H, Rubin, S.M.
Deposit date:2019-08-16
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae.
Plos Pathog., 16, 2020
2CD7
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BU of 2cd7 by Molmil
Staphylococcus aureus pI258 arsenate reductase (ArsC) H62Q mutant
Descriptor: PROTEIN ARSC, SODIUM ION
Authors:Buts, L, Roos, G, Van Belle, K, Brosens, E, Loris, R, Wyns, L, Messens, J.
Deposit date:2006-01-23
Release date:2006-06-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Interplay between Ion Binding and Catalysis in the Thioredoxin-Coupled Arsenate Reductase Family.
J.Mol.Biol., 360, 2006
3N8I
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BU of 3n8i by Molmil
Crystal structure of the A isoform of human cytoplasmic protein tyrosine phosphatase (HCPTP-A) in complex with 1-naphtylacetic acid
Descriptor: Low molecular weight phosphotyrosine protein phosphatase, NAPHTHALEN-1-YL-ACETIC ACID
Authors:Homan, K.T, Balasubramaniam, D, Stauffacher, C.V.
Deposit date:2010-05-28
Release date:2011-12-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Characterization of a Secondary Binding Site on Low Molecular Weight Protein Tyrosine Phosphatases
To be Published

 

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