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1OK7
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BU of 1ok7 by Molmil
A Conserved protein binding-site on Bacterial Sliding Clamps
Descriptor: DNA POLYMERASE III, DNA POLYMERASE IV
Authors:Burnouf, D.Y, Olieric, V, Wagner, J, Fujii, S, Reinbolt, J, Fuchs, R.P.P, Dumas, P.
Deposit date:2003-07-18
Release date:2004-07-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural and Biochemical Analysis of Sliding Clamp/Ligand Interactions Suggest a Competition between Replicative and Translesion DNA Polymerases
J.Mol.Biol., 335, 2004
5AH2
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BU of 5ah2 by Molmil
The sliding clamp of Mycobacterium smegmatis in complex with a natural product.
Descriptor: DNA POLYMERASE III SUBUNIT BETA, GRISELIMYCIN, SODIUM ION
Authors:Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
Deposit date:2015-02-04
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.129 Å)
Cite:Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
5M1S
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BU of 5m1s by Molmil
Cryo-EM structure of the E. coli replicative DNA polymerase-clamp-exonuclase-theta complex bound to DNA in the editing mode
Descriptor: DNA Primer Strand, DNA Template Strand, DNA polymerase III subunit alpha, ...
Authors:Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
Deposit date:2016-10-10
Release date:2017-01-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Self-correcting mismatches during high-fidelity DNA replication.
Nat. Struct. Mol. Biol., 24, 2017
7EVP
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BU of 7evp by Molmil
Cryo-EM structure of the Gp168-beta-clamp complex
Descriptor: Beta sliding clamp, Sliding clamp inhibitor
Authors:Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K.
Deposit date:2021-05-21
Release date:2022-02-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel.
Nucleic Acids Res., 49, 2021
3F1V
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BU of 3f1v by Molmil
E. coli Beta Sliding Clamp, 148-153 Ala Mutant
Descriptor: CALCIUM ION, CHLORIDE ION, DNA polymerase III subunit beta
Authors:Cody, V.
Deposit date:2008-10-28
Release date:2009-09-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Sliding clamp-DNA interactions are required for viability and contribute to DNA polymerase management in Escherichia coli.
J.Mol.Biol., 387, 2009
2XUR
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BU of 2xur by Molmil
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
Descriptor: DNA POLYMERASE III SUBUNIT BETA
Authors:Johnsen, L, Morigen, Dalhus, B, Bjoras, M, Flaatten, I, Waldminghaus, T, Skarstad, K.
Deposit date:2010-10-20
Release date:2011-02-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The G157C Mutation in the Escherichia Coli Sliding Clamp Specifically Affects Initiation of Replication.
Mol.Microbiol., 79, 2011
7RZM
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BU of 7rzm by Molmil
Crystal Structure of dnaN DNA polymerase III beta subunit from Stenotrophomonas maltophilia K279a
Descriptor: DNA polymerase III subunit beta
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-08-27
Release date:2021-10-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of dnaN DNA polymerase III beta subunit from Stenotrophomonas maltophilia K279a
To Be Published
7YBD
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BU of 7ybd by Molmil
Crystal structure of sliding DNA clamp of Clostridioides difficile
Descriptor: Beta sliding clamp, TRIETHYLENE GLYCOL
Authors:Hishiki, A, Okazaki, S, Hara, K, Hashimoto, H.
Deposit date:2022-06-29
Release date:2022-10-19
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal structure of the sliding DNA clamp from the Gram-positive anaerobic bacterium Clostridioides difficile.
J.Biochem., 173, 2022
5AGV
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BU of 5agv by Molmil
The sliding clamp of Mycobacterium tuberculosis in complex with a natural product.
Descriptor: (R,R)-2,3-BUTANEDIOL, CALCIUM ION, CYCLOHEXYL GRISELIMYCIN, ...
Authors:Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
Deposit date:2015-02-03
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
2POL
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BU of 2pol by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE BETA SUBUNIT OF ESCHERICHIA COLI DNA POLYMERASE III HOLOENZYME: A SLIDING DNA CLAMP
Descriptor: DNA POLYMERASE III (BETA SUBUNIT)
Authors:Kong, X.-P, Kuriyan, J.
Deposit date:1992-11-13
Release date:1994-01-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp.
Cell(Cambridge,Mass.), 69, 1992
5W7Z
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BU of 5w7z by Molmil
Crystal structure of DNA polymerase III subunit beta from Rickettsia conorii
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, DNA polymerase III subunit beta
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-06-21
Release date:2017-07-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of DNA polymerase III subunit beta from Rickettsia conorii
to be published
3D1G
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BU of 3d1g by Molmil
Structure of a small molecule inhibitor bound to a DNA sliding clamp
Descriptor: DNA polymerase III subunit beta, [(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid
Authors:Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M.
Deposit date:2008-05-05
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
5WCE
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BU of 5wce by Molmil
Caulobacter crescentus pol III beta
Descriptor: DNA polymerase III subunit beta
Authors:Oakley, A.J.
Deposit date:2017-06-30
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Pol III beta from Caulobacter crescentus
To Be Published
5AH4
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BU of 5ah4 by Molmil
The sliding clamp of Mycobacterium smegmatis in complex with a natural product.
Descriptor: CYCLOHEXYL GRISELIMYCIN, DNA POLYMERASE III SUBUNIT BETA, SODIUM ION
Authors:Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
Deposit date:2015-02-04
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.313 Å)
Cite:Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
6FVM
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BU of 6fvm by Molmil
Mutant DNA polymerase sliding clamp from Escherichia coli with bound P7 peptide
Descriptor: Beta sliding clamp, CALCIUM ION, GLYCEROL, ...
Authors:Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D.
Deposit date:2018-03-04
Release date:2019-04-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.631 Å)
Cite:Peptide Interactions on Bacterial Sliding Clamps.
Acs Infect Dis., 2019
3D1E
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BU of 3d1e by Molmil
Crystal structure of E. coli sliding clamp (beta) bound to a polymerase II peptide
Descriptor: DNA polymerase III subunit beta, decamer from polymerase II C-terminal
Authors:Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M.
Deposit date:2008-05-05
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008
6FVN
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BU of 6fvn by Molmil
DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide
Descriptor: Beta sliding clamp, P7 peptide
Authors:Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D.
Deposit date:2018-03-04
Release date:2019-04-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.142 Å)
Cite:Peptide Interactions on Bacterial Sliding Clamps.
Acs Infect Dis., 2019
5X06
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BU of 5x06 by Molmil
DNA replication regulation protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit beta, DnaA regulatory inactivator Hda, ...
Authors:Kim, J, Cho, Y.
Deposit date:2017-01-20
Release date:2018-01-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.237 Å)
Cite:Replication regulation protein
To Be Published
1UNN
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BU of 1unn by Molmil
Complex of beta-clamp processivity factor and little finger domain of PolIV
Descriptor: DNA POLYMERASE III BETA SUBUNIT, DNA POLYMERASE IV, SULFATE ION
Authors:Bunting, K.A, Roe, S.M, Pearl, L.H.
Deposit date:2003-09-11
Release date:2003-11-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Recruitment of Translesion DNA Polymerase Pol Iv/Dinb to the Beta-Clamp
Embo J., 22, 2003
5AGU
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BU of 5agu by Molmil
The sliding clamp of Mycobacterium tuberculosis in complex with a natural product.
Descriptor: (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA POLYMERASE III SUBUNIT BETA, ...
Authors:Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
Deposit date:2015-02-03
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.173 Å)
Cite:Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
3BEP
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BU of 3bep by Molmil
Structure of a sliding clamp on DNA
Descriptor: 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, DNA (5'-D(*DTP*DTP*DTP*DTP*DAP*DTP*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DG)-3'), DNA (5'-D(P*DCP*DCP*DCP*DAP*DTP*DCP*DGP*DTP*DAP*DT)-3'), ...
Authors:Georgescu, R.E, Kim, S.S, Yurieva, O, Kuriyan, J, Kong, X.-P, O'Donnell, M.
Deposit date:2007-11-19
Release date:2008-01-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of a sliding clamp on DNA
Cell(Cambridge,Mass.), 132, 2008
8PAT
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BU of 8pat by Molmil
Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 3.
Descriptor: ACE-GLN-ALC-GLX-LEU-PHE, Beta sliding clamp
Authors:Compain, G, Monsarrat, C, Blagojevic, J, Brillet, K, Dumas, P, Hammann, P, Kuhn, L, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Burnouf, D, Guichard, G.
Deposit date:2023-06-08
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp.
Jacs Au, 4, 2024
8PAY
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BU of 8pay by Molmil
Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 2.
Descriptor: ACE-GLN-ALC-GLC-LEU-PHE, Beta sliding clamp, GLYCEROL, ...
Authors:Compain, G, Monsarrat, C, Blagojevic, J, Brillet, K, Dumas, P, Hammann, P, Kuhn, L, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Burnouf, D, wagner, J, Guichard, G.
Deposit date:2023-06-08
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp.
Jacs Au, 4, 2024
1VPK
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BU of 1vpk by Molmil
Crystal structure of DNA polymerase III, beta subunit (TM0262) from Thermotoga maritima at 2.00 A resolution
Descriptor: DNA polymerase III, beta subunit
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2004-11-09
Release date:2004-11-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of DNA polymerase III, beta subunit (TM0262) from Thermotoga maritima at 2.00 A resolution
To be published
3D1F
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BU of 3d1f by Molmil
Crystal structure of E. coli sliding clamp (beta) bound to a polymerase III peptide
Descriptor: 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate, DI(HYDROXYETHYL)ETHER, DNA polymerase III subunit beta, ...
Authors:Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M.
Deposit date:2008-05-05
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Proc.Natl.Acad.Sci.Usa, 105, 2008

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