8PAT
Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 3.
Summary for 8PAT
| Entry DOI | 10.2210/pdb8pat/pdb |
| Descriptor | Beta sliding clamp, ACE-GLN-ALC-GLX-LEU-PHE (3 entities in total) |
| Functional Keywords | sliding clamp, covalent peptide, antibiotics, replication |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 2 |
| Total formula weight | 41677.74 |
| Authors | Compain, G.,Monsarrat, C.,Blagojevic, J.,Brillet, K.,Dumas, P.,Hammann, P.,Kuhn, L.,Martiel, I.,Engilberge, S.,Olieric, V.,Wolff, P.,Burnouf, D.,Guichard, G. (deposition date: 2023-06-08, release date: 2024-03-13) |
| Primary citation | Compain, G.,Monsarrat, C.,Blagojevic, J.,Brillet, K.,Dumas, P.,Hammann, P.,Kuhn, L.,Martiel, I.,Engilberge, S.,Olieric, V.,Wolff, P.,Burnouf, D.Y.,Wagner, J.,Guichard, G. Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp. Jacs Au, 4:432-440, 2024 Cited by PubMed: 38425897DOI: 10.1021/jacsau.3c00572 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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