Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2KXL
DownloadVisualize
BU of 2kxl by Molmil
Solution structure of a bacterial cyclic nucleotide-activated K+ channel binding domain in the unliganded state
Descriptor: Cyclic nucleotide-gated potassium channel mll3241
Authors:Schunke, S, Stoldt, M, Willbold, D.
Deposit date:2010-05-10
Release date:2011-04-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel.
Proc.Natl.Acad.Sci.USA, 108, 2011
5T3N
DownloadVisualize
BU of 5t3n by Molmil
Sp-2Cl-cAMPS bound to PKAR CBD2
Descriptor: (2S,4aR,6R,7R,7aS)-6-(6-amino-2-chloro-9H-purin-9-yl)-7-hydroxy-2-sulfanyltetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-2-one, IODIDE ION, cAMP-dependent protein kinase regulatory subunit
Authors:Littler, D.R, Gilson, P.
Deposit date:2016-08-26
Release date:2016-10-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.
J. Biol. Chem., 291, 2016
4D7T
DownloadVisualize
BU of 4d7t by Molmil
Structure of the SthK Carboxy-Terminal Region in complex with cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, STHK_CNBD_CAMP
Authors:Kesters, D, Brams, M, Nys, M, Wijckmans, E, Spurny, R, Voets, T, Tytgat, J, Ulens, C.
Deposit date:2014-11-27
Release date:2015-02-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.582 Å)
Cite:Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels.
Plos One, 10, 2015
4D7S
DownloadVisualize
BU of 4d7s by Molmil
Structure of the SthK Carboxy-Terminal Region in complex with cGMP
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, STHK_CNBD_CGMP
Authors:Kesters, D, Brams, M, Nys, M, Wijckmans, E, Spurny, R, Voets, T, Tytgat, J, Ulens, C.
Deposit date:2014-11-27
Release date:2015-02-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels.
Plos One, 10, 2015
6NP6
DownloadVisualize
BU of 6np6 by Molmil
Crystal structure of the sensor domain of the transcriptional regulator HcpR from Porphyromonas Gingivalis
Descriptor: Crp/Fnr family transcriptional regulator, GLYCEROL
Authors:Musayev, F.N, Belvin, B.R, Escalante, C.R, Turner, J, Scarsdale, J.N, Lewis, J.P.
Deposit date:2019-01-17
Release date:2019-06-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Nitrosative Stress Sensing in Porphyromonas gingivalis: Structure and Mechanisms of the Heme Binding Transcriptional Regulator HcpR.
Acta Crystallogr D Struct Biol, 75, 2019
4Z07
DownloadVisualize
BU of 4z07 by Molmil
Co-crystal structure of the tandem CNB (CNB-A/B) domains of human PKG I beta with cGMP
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, ISOPROPYL ALCOHOL, SULFATE ION, ...
Authors:Kim, J.J, Reger, A.S, Arold, S.T, Kim, C.
Deposit date:2015-03-25
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation.
Structure, 24, 2016
5BV6
DownloadVisualize
BU of 5bv6 by Molmil
PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with cGMP
Descriptor: ACETATE ION, CALCIUM ION, GUANOSINE-3',5'-MONOPHOSPHATE, ...
Authors:Campbell, J.C, Reger, A.S, Huang, G.Y, Sankaran, B, Kim, J.J, Kim, C.W.
Deposit date:2015-06-04
Release date:2016-01-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II.
J.Biol.Chem., 291, 2016
1CX4
DownloadVisualize
BU of 1cx4 by Molmil
CRYSTAL STRUCTURE OF A DELETION MUTANT OF THE TYPE II BETA REGULATORY SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT TYPE II BETA
Authors:Diller, T.C, Xuong, N.H, Taylor, S.S.
Deposit date:1999-08-28
Release date:2001-03-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit.
Structure, 9, 2001
2D93
DownloadVisualize
BU of 2d93 by Molmil
Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6
Descriptor: Rap guanine nucleotide exchange factor 6
Authors:Inoue, K, Muto, Y, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-08
Release date:2006-06-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6
to be published
4QX5
DownloadVisualize
BU of 4qx5 by Molmil
Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: Insights for PKG agonist design
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, IODIDE ION, cGMP-dependent protein kinase 1
Authors:Huang, G.Y, Gerlits, O.O, Blakeley, M.P, Sankaran, B, Kovalevsky, A.Y, Kim, C.
Deposit date:2014-07-18
Release date:2014-11-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.318 Å)
Cite:Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design.
Biochemistry, 53, 2014
4QXK
DownloadVisualize
BU of 4qxk by Molmil
Joint X-ray/neutron structure of PKGIbeta in complex with cGMP
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, SODIUM ION, cGMP-dependent protein kinase 1
Authors:Kim, C, Gerlits, O, Kovalevsky, A, Huang, G.Y.
Deposit date:2014-07-21
Release date:2014-11-12
Last modified:2024-02-28
Method:NEUTRON DIFFRACTION (2.2 Å), X-RAY DIFFRACTION
Cite:Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design.
Biochemistry, 53, 2014
3MDP
DownloadVisualize
BU of 3mdp by Molmil
Crystal structure of a Putative Cyclic nucleotide-binding protein (Gmet_1532) from Geobacter metallireducens GS-15 at 1.90 A resolution
Descriptor: 1,2-ETHANEDIOL, Cyclic nucleotide-binding domain (CNMP-BD) protein, SUCCINIC ACID
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-03-30
Release date:2010-05-19
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a Putative Cyclic nucleotide-binding protein (Gmet_1532) from Geobacter metallireducens GS-15 at 1.90 A resolution
To be published
5H5O
DownloadVisualize
BU of 5h5o by Molmil
A cyclic-GMP-dependent signalling pathway regulates bacterial phytopathogenesis
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Diguanylate cyclase
Authors:Chin, K.H, Chou, S.-H.
Deposit date:2016-11-08
Release date:2017-05-24
Method:X-RAY DIFFRACTION (2.122 Å)
Cite:A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis
EMBO J., 32, 2013
6SYG
DownloadVisualize
BU of 6syg by Molmil
Crystal structure of the Cyclic Nucleotide-Binding Homology Domain of the human KCNH2 channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Ben-Bassat, A, Giladi, M, Haitin, Y.
Deposit date:2019-09-27
Release date:2020-03-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of KCNH2 cyclic nucleotide-binding homology domain reveals a functionally vital salt-bridge.
J.Gen.Physiol., 152, 2020
5J3U
DownloadVisualize
BU of 5j3u by Molmil
Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Protein Kinase A
Authors:El Bakkouri, M, Walker, J.R, Tempel, W, Loppnau, P, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lin, L, Structural Genomics Consortium (SGC)
Deposit date:2016-03-31
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Co-crystal structure of the regulatory domain of Toxoplasma gondii PKA with cAMP
To Be Published
5J48
DownloadVisualize
BU of 5j48 by Molmil
PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-pCPT-cGMP
Descriptor: 1,2-ETHANEDIOL, 2-amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-3,9-dihydro-6H-purin-6-one, CALCIUM ION, ...
Authors:Campbell, J.C, Sankaran, B, Kim, C.W.
Deposit date:2016-03-31
Release date:2017-04-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural Basis of Analog Specificity in PKG I and II.
ACS Chem. Biol., 12, 2017
1RL3
DownloadVisualize
BU of 1rl3 by Molmil
Crystal structure of cAMP-free R1a subunit of PKA
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory chain
Authors:Wu, J, Brown, S, Xuong, N.-H, Taylor, S.S.
Deposit date:2003-11-24
Release date:2004-07-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RIalpha subunit of PKA: a cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B.
Structure, 12, 2004
1U12
DownloadVisualize
BU of 1u12 by Molmil
M. loti cyclic nucleotide binding domain mutant
Descriptor: IODIDE ION, POTASSIUM ION, SULFATE ION, ...
Authors:Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H.
Deposit date:2004-07-14
Release date:2004-11-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Ligand Activation in a Cyclic Nucleotide Regulated Potassium Channel
Cell(Cambridge,Mass.), 119, 2004
1RGS
DownloadVisualize
BU of 1rgs by Molmil
REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP DEPENDENT PROTEIN KINASE
Authors:Su, Y, Dostmann, W.R.G, Herberg, F.W, Durick, K, Xuong, N.-H, Ten Eyck, L, Taylor, S.S, Varughese, K.I.
Deposit date:1995-06-21
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains.
Science, 269, 1995
1VP6
DownloadVisualize
BU of 1vp6 by Molmil
M.loti ion channel cylic nucleotide binding domain
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BROMIDE ION, Cyclic-nucleotide binding domain of mesorhizobium loti CNG potassium channel
Authors:Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H.
Deposit date:2004-10-14
Release date:2004-10-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel.
Cell(Cambridge,Mass.), 119, 2004
4F8A
DownloadVisualize
BU of 4f8a by Molmil
Cyclic nucleotide binding-homology domain from mouse EAG1 potassium channel
Descriptor: Potassium voltage-gated channel subfamily H member 1
Authors:Marques-Carvalho, M.J, Sahoo, N, Muskett, F.W, Vieira-Pires, R.S, Gabant, G, Cadene, M, Schonherr, R, Morais-Cabral, J.H.
Deposit date:2012-05-17
Release date:2012-07-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel.
J.Mol.Biol., 423, 2012
4HBN
DownloadVisualize
BU of 4hbn by Molmil
Crystal structure of the human HCN4 channel C-terminus carrying the S672R mutation
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Xu, X, Marni, F, Wu, X, Su, Z, Musayev, F, Shrestha, S, Xie, C, Gao, W, Liu, Q, Zhou, L.
Deposit date:2012-09-28
Release date:2013-01-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel.
Structure, 20, 2012
2K0G
DownloadVisualize
BU of 2k0g by Molmil
Solution Structure of a Bacterial Cyclic Nucleotide-Activated K+ Channel Binding Domain in Complex with cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Mll3241 protein
Authors:Schunke, S, Stoldt, M, Willbold, D.
Deposit date:2008-02-02
Release date:2009-02-10
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP.
Embo Rep., 10, 2009
2Z69
DownloadVisualize
BU of 2z69 by Molmil
Crystal Structure of the sensor domain of the transcriptional regulator DNR from Pseudomonas aeruginosa
Descriptor: DNR protein
Authors:Giardina, G, Johnson, K.A, Di Matteo, A.
Deposit date:2007-07-24
Release date:2008-03-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR.
J.Mol.Biol., 378, 2008
2MHF
DownloadVisualize
BU of 2mhf by Molmil
Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
Descriptor: Uncharacterized protein
Authors:Li, Q, Ng, H.
Deposit date:2013-11-21
Release date:2014-04-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel.
J.Struct.Biol., 186, 2014

225158

건을2024-09-18부터공개중

PDB statisticsPDBj update infoContact PDBjnumon